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Breast granuloma

MedGen UID:
1053878
•Concept ID:
CN377467
•
Finding
Synonym: Granulomatous mastitis
 
HPO: HP:6000635

Definition

Formation of a non-necrotizing granuloma in breat tissue typically in combination with a localized infiltrate of multi-nucleated giant cells, epithelioid histiocytes, lymphocytes, and plasma cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast granuloma

Professional guidelines

PubMed

Idiopathic granulomatous mastitis: clinical, histopathological, and radiological characteristics and management approaches.
Azzam MI, Alnaimat F, Al-Nazer MW, Awad H, Odeh G, Al-Najar M, Alsayed S, El-Asir L, Addasi R, Melhem JM, Sweiss NJ
Rheumatol Int 2023 Oct;43(10):1859-1869. Epub 2023 Jun 22 doi: 10.1007/s00296-023-05375-6. PMID: 37347273
Idiopathic Granulomatous Mastitis: Etiology, Clinical Manifestation, Diagnosis and Treatment.
Yin Y, Liu X, Meng Q, Han X, Zhang H, Lv Y
J Invest Surg 2022 Mar;35(3):709-720. Epub 2021 Mar 10 doi: 10.1080/08941939.2021.1894516. PMID: 33691563
Idiopathic granulomatous mastitis: presentation, investigation and management.
Benson JR, Dumitru D
Future Oncol 2016 Jun;12(11):1381-94. Epub 2016 Apr 12 doi: 10.2217/fon-2015-0038. PMID: 27067146

Recent clinical studies

Etiology

Idiopathic granulomatous mastitis--a prospective study of 49 women and treatment outcomes with steroid therapy.
Pandey TS, Mackinnon JC, Bressler L, Millar A, Marcus EE, Ganschow PS
Breast J 2014 May-Jun;20(3):258-66. Epub 2014 Mar 27 doi: 10.1111/tbj.12263. PMID: 24673796

Diagnosis

Breast granuloma and C.R.S.T. syndrome.
Laroche M, Moulinier L, Bon E, Guiraud G, Cantagrel A, Hoff J, Mazieres B
Clin Rheumatol 1994 Sep;13(3):543-4. doi: 10.1007/BF02242961. PMID: 7835027

Therapy

Idiopathic granulomatous mastitis--a prospective study of 49 women and treatment outcomes with steroid therapy.
Pandey TS, Mackinnon JC, Bressler L, Millar A, Marcus EE, Ganschow PS
Breast J 2014 May-Jun;20(3):258-66. Epub 2014 Mar 27 doi: 10.1111/tbj.12263. PMID: 24673796

Clinical prediction guides

Idiopathic granulomatous mastitis--a prospective study of 49 women and treatment outcomes with steroid therapy.
Pandey TS, Mackinnon JC, Bressler L, Millar A, Marcus EE, Ganschow PS
Breast J 2014 May-Jun;20(3):258-66. Epub 2014 Mar 27 doi: 10.1111/tbj.12263. PMID: 24673796

Supplemental Content

Table of contents

    Clinical resources

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    Reviews

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    • PMC Articles
      Related information in PubMed Central Links
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