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Elevated circulating CXCL10 concentration

MedGen UID:
1053989
Concept ID:
CN377317
Finding
HPO: HP:6000486

Definition

The concentration of C-X-C motif chemokine 10 (CXCL10) in the blood circulation is above the upper limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated circulating CXCL10 concentration

Professional guidelines

PubMed

Martonik D, Parfieniuk-Kowerda A, Starosz A, Grubczak K, Moniuszko M, Flisiak R
Front Immunol 2023;14:1222170. Epub 2023 Jul 6 doi: 10.3389/fimmu.2023.1222170. PMID: 37483627Free PMC Article

Recent clinical studies

Etiology

Hirsch K, Nolley S, Ralph DD, Zheng Y, Altemeier WA, Rhodes CJ, Morrell NW, Wilkins MR, Leary PJ, Rayner SG
J Heart Lung Transplant 2023 Feb;42(2):173-182. Epub 2022 Nov 7 doi: 10.1016/j.healun.2022.10.026. PMID: 36470771Free PMC Article
Li N, He F, Gao H, Ge Y, Fan X, Zhang J, Qi H, Ren L
J Cell Physiol 2020 Dec;235(12):9577-9588. Epub 2020 May 7 doi: 10.1002/jcp.29766. PMID: 32383175
Mertens JS, de Jong EMGJ, van den Hoogen LL, Wienke J, Thurlings RM, Seyger MMB, Hoppenreijs EPAH, Wijngaarde CA, van Vlijmen-Willems IMJJ, van den Bogaard E, Giovannone B, van Wijk F, van Royen-Kerkhof A, Marut W, Radstake TRD
J Autoimmun 2019 Jul;101:86-93. Epub 2019 Apr 18 doi: 10.1016/j.jaut.2019.04.008. PMID: 31006523
Chalin A, Lefevre B, Devisme C, Pronier C, Carrière V, Thibault V, Amiot L, Samson M
Cytokine 2018 Nov;111:500-504. Epub 2018 Jun 4 doi: 10.1016/j.cyto.2018.05.029. PMID: 29880273
Nureki S, Miyazaki E, Ando M, Ueno T, Fukami T, Kumamoto T, Sugisaki K, Tsuda T
Respir Med 2008 Feb;102(2):239-47. Epub 2007 Oct 18 doi: 10.1016/j.rmed.2007.09.006. PMID: 17949965

Diagnosis

Martonik D, Parfieniuk-Kowerda A, Starosz A, Grubczak K, Moniuszko M, Flisiak R
Front Immunol 2023;14:1222170. Epub 2023 Jul 6 doi: 10.3389/fimmu.2023.1222170. PMID: 37483627Free PMC Article
Mertens JS, de Jong EMGJ, van den Hoogen LL, Wienke J, Thurlings RM, Seyger MMB, Hoppenreijs EPAH, Wijngaarde CA, van Vlijmen-Willems IMJJ, van den Bogaard E, Giovannone B, van Wijk F, van Royen-Kerkhof A, Marut W, Radstake TRD
J Autoimmun 2019 Jul;101:86-93. Epub 2019 Apr 18 doi: 10.1016/j.jaut.2019.04.008. PMID: 31006523
Chalin A, Lefevre B, Devisme C, Barget N, Amiot L, Samson M
Cytokine 2019 May;117:72-78. Epub 2019 Feb 28 doi: 10.1016/j.cyto.2019.02.006. PMID: 30826602
Ibitokou SA, Boström S, Brutus L, Tuikue Ndam N, Vianou B, Agbowaï C, Amadoudji Zin M, Huynh BT, Massougbodji A, Deloron P, Troye-Blomberg M, Fievet N, Luty AJ
Clin Vaccine Immunol 2014 Jun;21(6):859-66. Epub 2014 Apr 9 doi: 10.1128/CVI.00009-14. PMID: 24717969Free PMC Article
Molvarec A, Szarka A, Walentin S, Beko G, Karádi I, Prohászka Z, Rigó J Jr
Reprod Biol Endocrinol 2011 Sep 9;9:124. doi: 10.1186/1477-7827-9-124. PMID: 21906313Free PMC Article

Therapy

Martonik D, Parfieniuk-Kowerda A, Starosz A, Grubczak K, Moniuszko M, Flisiak R
Front Immunol 2023;14:1222170. Epub 2023 Jul 6 doi: 10.3389/fimmu.2023.1222170. PMID: 37483627Free PMC Article
Sturt AS, Webb EL, Patterson C, Phiri CR, Mweene T, Kjetland EF, Mudenda M, Mapani J, Mutengo MM, Chipeta J, van Dam GJ, Corstjens PLAM, Ayles H, Hayes RJ, Hansingo I, Cools P, van Lieshout L, Helmby H, McComsey GA, Francis SC, Bustinduy AL
Front Immunol 2021;12:620657. Epub 2021 Mar 2 doi: 10.3389/fimmu.2021.620657. PMID: 33737927Free PMC Article
Jiang H, Gebhardt C, Umansky L, Beckhove P, Schulze TJ, Utikal J, Umansky V
Int J Cancer 2015 May 15;136(10):2352-60. Epub 2014 Nov 12 doi: 10.1002/ijc.29297. PMID: 25353097
Pranzatelli MR, Tate ED, McGee NR, Travelstead AL, Colliver JA, Ness JM, Ransohoff RM
J Neuroinflammation 2013 Jan 16;10:10. doi: 10.1186/1742-2094-10-10. PMID: 23324534Free PMC Article
Ward SE, Loutfy MR, Blatt LM, Siminovitch KA, Chen J, Hinek A, Wolff B, Pham DH, Deif H, LaMere EA, Kain KC, Farcas GA, Ferguson P, Latchford M, Levy G, Fung L, Dennis JW, Lai EK, Fish EN
Antivir Ther 2005;10(2):263-75. PMID: 15865221

Prognosis

Jiang H, Gebhardt C, Umansky L, Beckhove P, Schulze TJ, Utikal J, Umansky V
Int J Cancer 2015 May 15;136(10):2352-60. Epub 2014 Nov 12 doi: 10.1002/ijc.29297. PMID: 25353097
Ibitokou SA, Boström S, Brutus L, Tuikue Ndam N, Vianou B, Agbowaï C, Amadoudji Zin M, Huynh BT, Massougbodji A, Deloron P, Troye-Blomberg M, Fievet N, Luty AJ
Clin Vaccine Immunol 2014 Jun;21(6):859-66. Epub 2014 Apr 9 doi: 10.1128/CVI.00009-14. PMID: 24717969Free PMC Article
Ostadebrahimi H, Jamali Z, Nazari M, Bahri M, Farahmandnia Z, Khandany BK, Taheri M, Khorramdelazad H, Hakimizadeh E, Zaker F, Rezaeian M, Hassanshahi G
Clin Lab 2014;60(1):99-104. doi: 10.7754/clin.lab.2013.121237. PMID: 24600982
Ward SE, Loutfy MR, Blatt LM, Siminovitch KA, Chen J, Hinek A, Wolff B, Pham DH, Deif H, LaMere EA, Kain KC, Farcas GA, Ferguson P, Latchford M, Levy G, Fung L, Dennis JW, Lai EK, Fish EN
Antivir Ther 2005;10(2):263-75. PMID: 15865221

Clinical prediction guides

Hirsch K, Nolley S, Ralph DD, Zheng Y, Altemeier WA, Rhodes CJ, Morrell NW, Wilkins MR, Leary PJ, Rayner SG
J Heart Lung Transplant 2023 Feb;42(2):173-182. Epub 2022 Nov 7 doi: 10.1016/j.healun.2022.10.026. PMID: 36470771Free PMC Article
Matsuoka N, Fujita Y, Temmoku J, Furuya MY, Asano T, Sato S, Matsumoto H, Kobayashi H, Watanabe H, Suzuki E, Kozuru H, Yastuhashi H, Migita K
PLoS One 2020;15(1):e0227069. Epub 2020 Jan 27 doi: 10.1371/journal.pone.0227069. PMID: 31986153Free PMC Article
Mertens JS, de Jong EMGJ, van den Hoogen LL, Wienke J, Thurlings RM, Seyger MMB, Hoppenreijs EPAH, Wijngaarde CA, van Vlijmen-Willems IMJJ, van den Bogaard E, Giovannone B, van Wijk F, van Royen-Kerkhof A, Marut W, Radstake TRD
J Autoimmun 2019 Jul;101:86-93. Epub 2019 Apr 18 doi: 10.1016/j.jaut.2019.04.008. PMID: 31006523
Ostadebrahimi H, Jamali Z, Nazari M, Bahri M, Farahmandnia Z, Khandany BK, Taheri M, Khorramdelazad H, Hakimizadeh E, Zaker F, Rezaeian M, Hassanshahi G
Clin Lab 2014;60(1):99-104. doi: 10.7754/clin.lab.2013.121237. PMID: 24600982
Molvarec A, Szarka A, Walentin S, Beko G, Karádi I, Prohászka Z, Rigó J Jr
Reprod Biol Endocrinol 2011 Sep 9;9:124. doi: 10.1186/1477-7827-9-124. PMID: 21906313Free PMC Article

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