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Positive stool Giardia antigen test

MedGen UID:
1054058
•Concept ID:
CN377133
•
Finding
HPO: HP:6000324

Definition

Fecal analysis for Giardia antigen is abnormal. Tests include direct fluorescent-antibody (DFA), which detect sintact organisms, and enzyme immunoassays (EIAs), which detect soluble stool antigens. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPositive stool Giardia antigen test

Recent clinical studies

Etiology

Giardia lamblia infection and associated risk factors among patients attending Kochore Health Center, Ethiopia.
Hajare ST, Betcha A, Sharma RJ, Bhosale SB, Upadhye VJ, Kuddus M, Eriso F
Infect Dis Now 2022 Aug;52(5):311-314. Epub 2022 Apr 25 doi: 10.1016/j.idnow.2022.04.005. PMID: 35483635
Reactivation of latent infections in solid organ transplant recipients from sub-Saharan Africa: What should be remembered?
Silva JT, Fernández-Ruiz M, Grossi PA, Hernández-Jimenez P, López-Medrano F, Mularoni A, Prista-Leão B, Santos L, Aguado JM
Transplant Rev (Orlando) 2021 Dec;35(4):100632. Epub 2021 Jun 2 doi: 10.1016/j.trre.2021.100632. PMID: 34130253
Epidemiology of Intestinal Parasites in a University Hospital in Northern Cyprus: A 4-year Retrospective Experience.
Güler E, Süer K
Turkiye Parazitol Derg 2021 Jun 7;45(2):128-132. doi: 10.4274/tpd.galenos.2021.6847. PMID: 34103290
Intestinal protozoan infections among Egyptian neutropenic patients with acute leukemia.
Zaki NE, Hamed NA, Sadek NA, Mishriky RI, Abd El-Latif NF, Mikhael IL
Trop Biomed 2021 Mar 1;38(1):50-56. doi: 10.47665/tb.38.1.009. PMID: 33797524
COMPARISON OF IMMUNOCHROMATOGRAPHIC TEST AND MICROSCOPY IN THE DETECTION OF SOME ENTERIC PROTOZOA IN STOOL SAMPLES.
Atia MM, Elsettawy MA, Fathy GM, Salama MA, Metally Ashoush SEM
J Egypt Soc Parasitol 2016 Dec;46(3):625-632. PMID: 30230759

Diagnosis

The incidence of laboratory-confirmed cases of enteric pathogens in Denmark 2018: a national observational study.
Svendsen AT, Nielsen HL, Bytzer P, Coia JE, Engberg J, Holt HM, Lemming L, Lomborg S, Marmolin ES, Olesen BS, Andersen LP, Ethelberg S, Engsbro AL
Infect Dis (Lond) 2023 May;55(5):340-350. Epub 2023 Mar 3 doi: 10.1080/23744235.2023.2183253. PMID: 36868794
Canine nematode and Giardia spp. infections in dogs in Edmonton, Alberta, the "CANIDA" study.
Visscher D, Porter E, Sweet S, Szlosek D, Horr S
Parasit Vectors 2022 Aug 22;15(1):294. doi: 10.1186/s13071-022-05386-5. PMID: 35996178Free PMC Article
Giardia lamblia infection and associated risk factors among patients attending Kochore Health Center, Ethiopia.
Hajare ST, Betcha A, Sharma RJ, Bhosale SB, Upadhye VJ, Kuddus M, Eriso F
Infect Dis Now 2022 Aug;52(5):311-314. Epub 2022 Apr 25 doi: 10.1016/j.idnow.2022.04.005. PMID: 35483635
Reactivation of latent infections in solid organ transplant recipients from sub-Saharan Africa: What should be remembered?
Silva JT, Fernández-Ruiz M, Grossi PA, Hernández-Jimenez P, López-Medrano F, Mularoni A, Prista-Leão B, Santos L, Aguado JM
Transplant Rev (Orlando) 2021 Dec;35(4):100632. Epub 2021 Jun 2 doi: 10.1016/j.trre.2021.100632. PMID: 34130253
Intestinal protozoan infections among Egyptian neutropenic patients with acute leukemia.
Zaki NE, Hamed NA, Sadek NA, Mishriky RI, Abd El-Latif NF, Mikhael IL
Trop Biomed 2021 Mar 1;38(1):50-56. doi: 10.47665/tb.38.1.009. PMID: 33797524

Therapy

Reactivation of latent infections in solid organ transplant recipients from sub-Saharan Africa: What should be remembered?
Silva JT, Fernández-Ruiz M, Grossi PA, Hernández-Jimenez P, López-Medrano F, Mularoni A, Prista-Leão B, Santos L, Aguado JM
Transplant Rev (Orlando) 2021 Dec;35(4):100632. Epub 2021 Jun 2 doi: 10.1016/j.trre.2021.100632. PMID: 34130253
Performance of three rapid diagnostic tests for the detection of Cryptosporidium spp. and Giardia duodenalis in children with severe acute malnutrition and diarrhoea.
Bitilinyu-Bangoh J, Voskuijl W, Thitiri J, Menting S, Verhaar N, Mwalekwa L, de Jong DB, van Loenen M, Mens PF, Berkley JA, Bandsma RHJ, Schallig HDFH
Infect Dis Poverty 2019 Nov 28;8(1):96. doi: 10.1186/s40249-019-0609-6. PMID: 31775877Free PMC Article
Giardia intestinalis in patients with nonulcer dyspepsia.
Abulhasan M, Elshazly TA, Eida M, Albadry A
Arab J Gastroenterol 2013 Sep;14(3):126-9. Epub 2013 Sep 19 doi: 10.1016/j.ajg.2013.08.004. PMID: 24206742
Monitoring nonresponsive patients who have celiac disease.
Krauss N, Schuppan D
Gastrointest Endosc Clin N Am 2006 Apr;16(2):317-27. doi: 10.1016/j.giec.2006.03.005. PMID: 16644460
Stool diagnosis of giardiasis using a commercially available enzyme immunoassay to detect Giardia-specific antigen 65 (GSA 65).
Rosoff JD, Sanders CA, Sonnad SS, De Lay PR, Hadley WK, Vincenzi FF, Yajko DM, O'Hanley PD
J Clin Microbiol 1989 Sep;27(9):1997-2002. doi: 10.1128/jcm.27.9.1997-2002.1989. PMID: 2674196Free PMC Article

Prognosis

The incidence of laboratory-confirmed cases of enteric pathogens in Denmark 2018: a national observational study.
Svendsen AT, Nielsen HL, Bytzer P, Coia JE, Engberg J, Holt HM, Lemming L, Lomborg S, Marmolin ES, Olesen BS, Andersen LP, Ethelberg S, Engsbro AL
Infect Dis (Lond) 2023 May;55(5):340-350. Epub 2023 Mar 3 doi: 10.1080/23744235.2023.2183253. PMID: 36868794
Crypto-Giardia antigen rapid test versus conventional modified Ziehl-Neelsen acid fast staining method for diagnosis of cryptosporidiosis.
Zaglool DA, Mohamed A, Khodari YA, Farooq MU
Asian Pac J Trop Med 2013 Mar;6(3):212-5. doi: 10.1016/S1995-7645(13)60025-5. PMID: 23375035
Monitoring nonresponsive patients who have celiac disease.
Krauss N, Schuppan D
Gastrointest Endosc Clin N Am 2006 Apr;16(2):317-27. doi: 10.1016/j.giec.2006.03.005. PMID: 16644460
Evaluation of the immunochromatographic CORIS Giardia-Strip test for rapid diagnosis of Giardia lamblia.
Oster N, Gehrig-Feistel H, Jung H, Kammer J, McLean JE, Lanzer M
Eur J Clin Microbiol Infect Dis 2006 Feb;25(2):112-5. doi: 10.1007/s10096-006-0088-0. PMID: 16447062
A double-antibody sandwich ELISA for the detection of Entamoeba histolytica antigen in stool samples of humans.
Baumann D, Gottstein B
Trop Med Parasitol 1987 Jun;38(2):81-5. PMID: 2888183

Clinical prediction guides

The incidence of laboratory-confirmed cases of enteric pathogens in Denmark 2018: a national observational study.
Svendsen AT, Nielsen HL, Bytzer P, Coia JE, Engberg J, Holt HM, Lemming L, Lomborg S, Marmolin ES, Olesen BS, Andersen LP, Ethelberg S, Engsbro AL
Infect Dis (Lond) 2023 May;55(5):340-350. Epub 2023 Mar 3 doi: 10.1080/23744235.2023.2183253. PMID: 36868794
Epidemiology of Intestinal Parasites in a University Hospital in Northern Cyprus: A 4-year Retrospective Experience.
Güler E, Süer K
Turkiye Parazitol Derg 2021 Jun 7;45(2):128-132. doi: 10.4274/tpd.galenos.2021.6847. PMID: 34103290
Crypto-Giardia antigen rapid test versus conventional modified Ziehl-Neelsen acid fast staining method for diagnosis of cryptosporidiosis.
Zaglool DA, Mohamed A, Khodari YA, Farooq MU
Asian Pac J Trop Med 2013 Mar;6(3):212-5. doi: 10.1016/S1995-7645(13)60025-5. PMID: 23375035
Evaluation of the immunochromatographic CORIS Giardia-Strip test for rapid diagnosis of Giardia lamblia.
Oster N, Gehrig-Feistel H, Jung H, Kammer J, McLean JE, Lanzer M
Eur J Clin Microbiol Infect Dis 2006 Feb;25(2):112-5. doi: 10.1007/s10096-006-0088-0. PMID: 16447062
A double-antibody sandwich ELISA for the detection of Entamoeba histolytica antigen in stool samples of humans.
Baumann D, Gottstein B
Trop Med Parasitol 1987 Jun;38(2):81-5. PMID: 2888183

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