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Focal T1 hyperintense brainstem lesion

MedGen UID:
1054259
•Concept ID:
CN377097
•
Finding
HPO: HP:6000286

Definition

A lighter than expected T1 signal on magnetic resonance imaging (MRI) of the brainstem. This term refers to a localized hyperintensity affecting a particular region of the brainstem. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal T1 hyperintense brainstem lesion

Professional guidelines

PubMed

The management of brainstem gliomas in patients with neurofibromatosis 1.
Pollack IF, Shultz B, Mulvihill JJ
Neurology 1996 Jun;46(6):1652-60. doi: 10.1212/wnl.46.6.1652. PMID: 8649565

Recent clinical studies

Etiology

Eight-and-a-half syndrome as the first presentation of multiple sclerosis in an Asian male: a case report.
Lim XY, Wai YZ, Yong YX, Lim LT
J Med Case Rep 2023 Mar 6;17(1):99. doi: 10.1186/s13256-022-03699-8. PMID: 36879252Free PMC Article
Multiple neuroenteric cysts at cerebello-pontine angle and foramen magnum: a case report and review of the literature.
Zarineh A, Leon ME, Saad RS, Silverman JF
Neuropathology 2009 Jun;29(3):318-22. Epub 2008 Aug 18 doi: 10.1111/j.1440-1789.2008.00958.x. PMID: 18715273
CT and MR imaging characteristics of intravestibular lipoma.
Dahlen RT, Johnson CE, Harnsberger HR, Biediger CP, Syms CA, Fischbein NJ, Schwartz JM
AJNR Am J Neuroradiol 2002 Sep;23(8):1413-7. PMID: 12223388Free PMC Article
Globular glioma of the tectum.
Antunes NL, Tavora L, Souweidane M
Pediatr Neurol 1999 Jul;21(1):492-5. doi: 10.1016/s0887-8994(99)00009-0. PMID: 10428437
The management of brainstem gliomas in patients with neurofibromatosis 1.
Pollack IF, Shultz B, Mulvihill JJ
Neurology 1996 Jun;46(6):1652-60. doi: 10.1212/wnl.46.6.1652. PMID: 8649565

Diagnosis

Eight-and-a-half syndrome as the first presentation of multiple sclerosis in an Asian male: a case report.
Lim XY, Wai YZ, Yong YX, Lim LT
J Med Case Rep 2023 Mar 6;17(1):99. doi: 10.1186/s13256-022-03699-8. PMID: 36879252Free PMC Article
Pandora's box: eosinophilic granuloma at the cerebellopontine angle-should we open it?
Öğrenci A, Batçık OE, Ekşi MŞ, Koban O
Childs Nerv Syst 2016 Aug;32(8):1513-6. Epub 2015 Dec 12 doi: 10.1007/s00381-015-2982-1. PMID: 26661575
Globular glioma of the tectum.
Antunes NL, Tavora L, Souweidane M
Pediatr Neurol 1999 Jul;21(1):492-5. doi: 10.1016/s0887-8994(99)00009-0. PMID: 10428437
Quantitative volumetric analysis of brain magnetic resonance imaging from patients with multiple sclerosis.
Filippi M, Mastronardo G, Rocca MA, Pereira C, Comi G
J Neurol Sci 1998 Jun 30;158(2):148-53. doi: 10.1016/s0022-510x(98)00110-5. PMID: 9702685
Cranial MRI in Wilson's disease.
Prayer L, Wimberger D, Kramer J, Grimm G, Oder W, Imhof H
Neuroradiology 1990;32(3):211-4. doi: 10.1007/BF00589114. PMID: 2215906

Therapy

Neuro-Behcet's disease mimicking multiple brain tumors: diffusion-weighted MR study and literature review.
Heo JH, Lee ST, Chu K, Kim M
J Neurol Sci 2008 Jan 15;264(1-2):177-81. Epub 2007 Sep 12 doi: 10.1016/j.jns.2007.07.029. PMID: 17850821
Cerebral microbleeds in CADASIL: a gradient-echo magnetic resonance imaging and autopsy study.
Dichgans M, Holtmannspötter M, Herzog J, Peters N, Bergmann M, Yousry TA
Stroke 2002 Jan;33(1):67-71. doi: 10.1161/hs0102.100885. PMID: 11779891

Prognosis

Eight-and-a-half syndrome as the first presentation of multiple sclerosis in an Asian male: a case report.
Lim XY, Wai YZ, Yong YX, Lim LT
J Med Case Rep 2023 Mar 6;17(1):99. doi: 10.1186/s13256-022-03699-8. PMID: 36879252Free PMC Article
Pandora's box: eosinophilic granuloma at the cerebellopontine angle-should we open it?
Öğrenci A, Batçık OE, Ekşi MŞ, Koban O
Childs Nerv Syst 2016 Aug;32(8):1513-6. Epub 2015 Dec 12 doi: 10.1007/s00381-015-2982-1. PMID: 26661575
Globular glioma of the tectum.
Antunes NL, Tavora L, Souweidane M
Pediatr Neurol 1999 Jul;21(1):492-5. doi: 10.1016/s0887-8994(99)00009-0. PMID: 10428437
The management of brainstem gliomas in patients with neurofibromatosis 1.
Pollack IF, Shultz B, Mulvihill JJ
Neurology 1996 Jun;46(6):1652-60. doi: 10.1212/wnl.46.6.1652. PMID: 8649565
Cranial MRI in Wilson's disease.
Prayer L, Wimberger D, Kramer J, Grimm G, Oder W, Imhof H
Neuroradiology 1990;32(3):211-4. doi: 10.1007/BF00589114. PMID: 2215906

Clinical prediction guides

Focal T2 hyperintensity in the dorsal brain stem in patients with vestibular schwannoma.
Okamoto K, Furusawa T, Ishikawa K, Sasai K, Tokiguchi S
AJNR Am J Neuroradiol 2006 Jun-Jul;27(6):1307-11. PMID: 16775286Free PMC Article
Cerebral microbleeds in CADASIL: a gradient-echo magnetic resonance imaging and autopsy study.
Dichgans M, Holtmannspötter M, Herzog J, Peters N, Bergmann M, Yousry TA
Stroke 2002 Jan;33(1):67-71. doi: 10.1161/hs0102.100885. PMID: 11779891
Quantitative volumetric analysis of brain magnetic resonance imaging from patients with multiple sclerosis.
Filippi M, Mastronardo G, Rocca MA, Pereira C, Comi G
J Neurol Sci 1998 Jun 30;158(2):148-53. doi: 10.1016/s0022-510x(98)00110-5. PMID: 9702685

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