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Reduced circulating squalene concentration

MedGen UID:: 1054378
•Concept ID:: CN377036
•: Finding

HPO:	HP:6000440

Definition

The concentration of squalene in the blood circulation is below the lower limit of normal. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVReduced circulating squalene concentration

Phenotypic abnormality
- Abnormality of metabolism/homeostasis
  - Abnormal circulating metabolite concentration
    - Abnormal circulating organic compound concentration
      - Reduced circulating squalene concentration

Recent clinical studies

Etiology

Novel LDL-oriented pharmacotherapeutical strategies.

Huang LZ, Zhu HB
Pharmacol Res 2012 Apr;65(4):402-10. Epub 2012 Jan 24 doi: 10.1016/j.phrs.2012.01.007. PMID: 22306845

Therapy

Novel LDL-oriented pharmacotherapeutical strategies.

Huang LZ, Zhu HB
Pharmacol Res 2012 Apr;65(4):402-10. Epub 2012 Jan 24 doi: 10.1016/j.phrs.2012.01.007. PMID: 22306845

Clinical prediction guides

The mechanism of the hypocholesterolaemic effect of activated charcoal.

Neuvonen PJ, Kuusisto P, Manninen V, Vapaatalo H, Miettinen TA
Eur J Clin Invest 1989 Jun;19(3):251-4. doi: 10.1111/j.1365-2362.1989.tb00226.x. PMID: 2509211

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ClinicalTrials.gov

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Reduced circulating squalene concentration
Reduced circulating squalene concentration

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