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Prostatic adenoma

MedGen UID:
105447
•Concept ID:
C0520477
•
Neoplastic Process
Synonyms: Adenoma, Prostatic; Adenomas, Prostatic; Prostatic Adenoma; Prostatic Adenomas
SNOMED CT: Benign adenoma of prostate (21173002); Adenoma of prostate (21173002)
 
Monarch Initiative: MONDO:0002450

Definition

Focal benign glandular hyperplasia in the prostate gland. [from NCI]

Professional guidelines

PubMed

Management of Benign Prostatic Hyperplasia Larger than 100 ml: Simple Open Enucleation Versus Transurethral Laser Prostatectomy.
Elkoushy MA, Elhilali MM
Curr Urol Rep 2016 Jun;17(6):44. doi: 10.1007/s11934-016-0601-7. PMID: 27048160
Update on the use of diode laser in the management of benign prostate obstruction in 2014.
Lusuardi L, Mitterberger M, Hruby S, Kunit T, Kloss B, Engelhardt PF, Sieberer M, Janetschek G
World J Urol 2015 Apr;33(4):555-62. Epub 2014 May 24 doi: 10.1007/s00345-014-1327-0. PMID: 24859776
Medical treatment of benign prostatic hyperplasia: 5 alpha-reductase inhibitors and alpha-adrenergic antagonists.
Monda JM, Oesterling JE
Mayo Clin Proc 1993 Jul;68(7):670-9. doi: 10.1016/s0025-6196(12)60603-x. PMID: 7688840

Recent clinical studies

Etiology

Enucleation of the prostate as retreatment for recurrent or residual benign prostatic obstruction: a systematic review and a meta-analysis.
Pyrgidis N, Mykoniatis I, Lusuardi L, Schulz GB, Sokolakis I, Stief C, Sountoulides P
Prostate Cancer Prostatic Dis 2023 Dec;26(4):693-701. Epub 2023 May 16 doi: 10.1038/s41391-023-00677-z. PMID: 37193777
Are Helicobacter Pylori and Benign Prostatic Hyperplasia Related, and If So, How?
Verit A, Yüksel ÖH, Kivrak M, Yazicilar HA, Özbay N, Uruç F
Urol J 2015 Sep 4;12(4):2271-5. PMID: 26341771
Neobladder with prostatic capsule and seminal-sparing cystectomy for bladder cancer: a step in the wrong direction.
Hautmann RE, Stein JP
Urol Clin North Am 2005 May;32(2):177-85. doi: 10.1016/j.ucl.2005.02.001. PMID: 15862615
Interstitial laser prostatectomy.
Perlmutter AP, Muschter R
Mayo Clin Proc 1998 Sep;73(9):903-7. doi: 10.4065/73.9.903. PMID: 9737231
Concentrations of cefpodoxime in plasma, ejaculate and in prostatic fluid and adenoma tissue.
Naber KG, Kinzig M, Adam D, Sörgel F, Bajorski AH, Kiehn R
Infection 1991 Jan-Feb;19(1):30-5. doi: 10.1007/BF01643755. PMID: 1707399

Diagnosis

Giant Pelvic Adenoma Originating from Ectopic Prostatic Tissue.
Lu XQ, Hu HP, Cong ZC, Yu JD
J Coll Physicians Surg Pak 2019 Mar;29(3):281-283. doi: 10.29271/jcpsp.2019.03.281. PMID: 30823960
Monopolar Transurethral Enucleation of Prostatic Adenoma: Preliminary Report.
Pansadoro V, Emiliozzi P, Del Vecchio G, Martini M, Scarpone P, Del Giudice F, Veneziano D, Brassetti A, Assenmacher C
Urology 2017 Apr;102:252-257. Epub 2017 Jan 10 doi: 10.1016/j.urology.2016.12.024. PMID: 28087281
Incidental prostatic cancer: repeat TURP or biopsy?
Martino P, Palazzo S, Battaglia M, Lucarelli G, Selvaggi FP
Urol Int 2004;73(3):193-7. doi: 10.1159/000080826. PMID: 15539835
Benign prostatic hyperplasia: correlations between receptor density and binding affinity of alpha(1)-adrenoceptors and several clinical parameters.
D'Addessi A, Martire M, Cannizzaro C, Porreca A, Menchinelli P, Alcini A, Alcini E
Urol Int 2002;68(4):246-50. doi: 10.1159/000058444. PMID: 12053026
Xanthogranulomatous prostatitis.
Miekoś E, Włodarczyk W, Szram S
Int Urol Nephrol 1986;18(4):433-7. doi: 10.1007/BF02084115. PMID: 3818220

Therapy

Enucleation of the prostate: An anatomical perspective.
Oh SJ, Shitara T
Andrologia 2020 Sep;52(8):e13744. Epub 2020 Jul 9 doi: 10.1111/and.13744. PMID: 32643827
Update on the use of diode laser in the management of benign prostate obstruction in 2014.
Lusuardi L, Mitterberger M, Hruby S, Kunit T, Kloss B, Engelhardt PF, Sieberer M, Janetschek G
World J Urol 2015 Apr;33(4):555-62. Epub 2014 May 24 doi: 10.1007/s00345-014-1327-0. PMID: 24859776
The surgical treatment of a large prostatic adenoma: the laparoscopic approach--a systematic review.
Asimakopoulos AD, Mugnier C, Hoepffner JL, Spera E, Vespasiani G, Gaston R, Antonini G, Piechaud T, Miano R
J Endourol 2012 Aug;26(8):960-7. Epub 2012 Apr 27 doi: 10.1089/end.2012.0055. PMID: 22417323
Interstitial laser prostatectomy.
Perlmutter AP, Muschter R
Mayo Clin Proc 1998 Sep;73(9):903-7. doi: 10.4065/73.9.903. PMID: 9737231
Medical treatment of benign prostatic hyperplasia: 5 alpha-reductase inhibitors and alpha-adrenergic antagonists.
Monda JM, Oesterling JE
Mayo Clin Proc 1993 Jul;68(7):670-9. doi: 10.1016/s0025-6196(12)60603-x. PMID: 7688840

Prognosis

Are Helicobacter Pylori and Benign Prostatic Hyperplasia Related, and If So, How?
Verit A, Yüksel ÖH, Kivrak M, Yazicilar HA, Özbay N, Uruç F
Urol J 2015 Sep 4;12(4):2271-5. PMID: 26341771
Can we predict the outcome of 532 nm laser photoselective vaporization of the prostate? Time to event analysis.
Elshal AM, Elmansy HM, Elhilali MM
J Urol 2012 Nov;188(5):1746-53. Epub 2012 Sep 19 doi: 10.1016/j.juro.2012.07.030. PMID: 22998906
Holmium laser enucleation for prostatic adenoma: analysis of learning curve over the course of 70 consecutive cases.
Seki N, Mochida O, Kinukawa N, Sagiyama K, Naito S
J Urol 2003 Nov;170(5):1847-50. doi: 10.1097/01.ju.0000092035.16351.9d. PMID: 14532790
Predicted and actual change in serum PSA following prostatectomy for BPH.
Lloyd SN, Collins GN, McKelvie GB, Hehir M, Rogers AC
Urology 1994 Apr;43(4):472-9. doi: 10.1016/0090-4295(94)90234-8. PMID: 7512298
Xanthogranulomatous prostatitis.
Miekoś E, Włodarczyk W, Szram S
Int Urol Nephrol 1986;18(4):433-7. doi: 10.1007/BF02084115. PMID: 3818220

Clinical prediction guides

Enucleation of the prostate as retreatment for recurrent or residual benign prostatic obstruction: a systematic review and a meta-analysis.
Pyrgidis N, Mykoniatis I, Lusuardi L, Schulz GB, Sokolakis I, Stief C, Sountoulides P
Prostate Cancer Prostatic Dis 2023 Dec;26(4):693-701. Epub 2023 May 16 doi: 10.1038/s41391-023-00677-z. PMID: 37193777
Monopolar Transurethral Enucleation of Prostatic Adenoma: Preliminary Report.
Pansadoro V, Emiliozzi P, Del Vecchio G, Martini M, Scarpone P, Del Giudice F, Veneziano D, Brassetti A, Assenmacher C
Urology 2017 Apr;102:252-257. Epub 2017 Jan 10 doi: 10.1016/j.urology.2016.12.024. PMID: 28087281
Are Helicobacter Pylori and Benign Prostatic Hyperplasia Related, and If So, How?
Verit A, Yüksel ÖH, Kivrak M, Yazicilar HA, Özbay N, Uruç F
Urol J 2015 Sep 4;12(4):2271-5. PMID: 26341771
Neobladder with prostatic capsule and seminal-sparing cystectomy for bladder cancer: a step in the wrong direction.
Hautmann RE, Stein JP
Urol Clin North Am 2005 May;32(2):177-85. doi: 10.1016/j.ucl.2005.02.001. PMID: 15862615
Xanthogranulomatous prostatitis.
Miekoś E, Włodarczyk W, Szram S
Int Urol Nephrol 1986;18(4):433-7. doi: 10.1007/BF02084115. PMID: 3818220

Recent systematic reviews

Enucleation of the prostate as retreatment for recurrent or residual benign prostatic obstruction: a systematic review and a meta-analysis.
Pyrgidis N, Mykoniatis I, Lusuardi L, Schulz GB, Sokolakis I, Stief C, Sountoulides P
Prostate Cancer Prostatic Dis 2023 Dec;26(4):693-701. Epub 2023 May 16 doi: 10.1038/s41391-023-00677-z. PMID: 37193777
The surgical treatment of a large prostatic adenoma: the laparoscopic approach--a systematic review.
Asimakopoulos AD, Mugnier C, Hoepffner JL, Spera E, Vespasiani G, Gaston R, Antonini G, Piechaud T, Miano R
J Endourol 2012 Aug;26(8):960-7. Epub 2012 Apr 27 doi: 10.1089/end.2012.0055. PMID: 22417323

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