U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Elevated circulating soluble CD163 concentration

MedGen UID:
1054807
•Concept ID:
CN376981
•
Finding
HPO: HP:6000385

Definition

The concentration of Soluble CD163 in the blood circulation is above the upper limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated circulating soluble CD163 concentration

Recent clinical studies

Etiology

The association of soluble CD163, a novel biomarker of macrophage activation, with type 2 diabetes mellitus and its underlying physiological disorders: A systematic review.
Semnani-Azad Z, Blanco Mejia S, Connelly PW, Bazinet RP, Retnakaran R, Jenkins DJA, Harris SB, Hanley AJ
Obes Rev 2021 Sep;22(9):e13257. Epub 2021 Apr 28 doi: 10.1111/obr.13257. PMID: 33913230
Soluble CD163-Associated Dietary Patterns and the Risk of Metabolic Syndrome.
Hu TY, Lee SY, Shih CK, Chou MJ, Wu MC, Teng IC, Bai CH, Sabrina N, Tinkov AA, Skalny AV, Chang JS
Nutrients 2019 Apr 25;11(4) doi: 10.3390/nu11040940. PMID: 31027316Free PMC Article
Impact of age and metabolic syndrome on the adipokine profile in childhood and adult obesity.
Weghuber D, Mangge H, Hochbrugger E, Stulnig TM
Exp Clin Endocrinol Diabetes 2014 Jun;122(6):363-7. Epub 2014 Jun 18 doi: 10.1055/s-0034-1375647. PMID: 24941433
Increased serum levels of soluble CD163 in patients with scleroderma.
Shimizu K, Ogawa F, Yoshizaki A, Akiyama Y, Kuwatsuka Y, Okazaki S, Tomita H, Takenaka M, Sato S
Clin Rheumatol 2012 Jul;31(7):1059-64. Epub 2012 Mar 29 doi: 10.1007/s10067-012-1972-x. PMID: 22453843

Diagnosis

Soluble CD163 is associated with body mass index and blood pressure in hypertensive obese Saudi patients.
Al-Daghri NM, Al-Attas OS, Bindahman LS, Alokail MS, Alkharfy KM, Draz HM, Yakout S, McTernan PG, Sabico S, Chrousos GP
Eur J Clin Invest 2012 Nov;42(11):1221-6. Epub 2012 Sep 4 doi: 10.1111/j.1365-2362.2012.02714.x. PMID: 22946776

Therapy

The association of soluble CD163, a novel biomarker of macrophage activation, with type 2 diabetes mellitus and its underlying physiological disorders: A systematic review.
Semnani-Azad Z, Blanco Mejia S, Connelly PW, Bazinet RP, Retnakaran R, Jenkins DJA, Harris SB, Hanley AJ
Obes Rev 2021 Sep;22(9):e13257. Epub 2021 Apr 28 doi: 10.1111/obr.13257. PMID: 33913230
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Impact of age and metabolic syndrome on the adipokine profile in childhood and adult obesity.
Weghuber D, Mangge H, Hochbrugger E, Stulnig TM
Exp Clin Endocrinol Diabetes 2014 Jun;122(6):363-7. Epub 2014 Jun 18 doi: 10.1055/s-0034-1375647. PMID: 24941433

Prognosis

The association of soluble CD163, a novel biomarker of macrophage activation, with type 2 diabetes mellitus and its underlying physiological disorders: A systematic review.
Semnani-Azad Z, Blanco Mejia S, Connelly PW, Bazinet RP, Retnakaran R, Jenkins DJA, Harris SB, Hanley AJ
Obes Rev 2021 Sep;22(9):e13257. Epub 2021 Apr 28 doi: 10.1111/obr.13257. PMID: 33913230
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Soluble CD163-Associated Dietary Patterns and the Risk of Metabolic Syndrome.
Hu TY, Lee SY, Shih CK, Chou MJ, Wu MC, Teng IC, Bai CH, Sabrina N, Tinkov AA, Skalny AV, Chang JS
Nutrients 2019 Apr 25;11(4) doi: 10.3390/nu11040940. PMID: 31027316Free PMC Article

Clinical prediction guides

The association of soluble CD163, a novel biomarker of macrophage activation, with type 2 diabetes mellitus and its underlying physiological disorders: A systematic review.
Semnani-Azad Z, Blanco Mejia S, Connelly PW, Bazinet RP, Retnakaran R, Jenkins DJA, Harris SB, Hanley AJ
Obes Rev 2021 Sep;22(9):e13257. Epub 2021 Apr 28 doi: 10.1111/obr.13257. PMID: 33913230
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Soluble CD163-Associated Dietary Patterns and the Risk of Metabolic Syndrome.
Hu TY, Lee SY, Shih CK, Chou MJ, Wu MC, Teng IC, Bai CH, Sabrina N, Tinkov AA, Skalny AV, Chang JS
Nutrients 2019 Apr 25;11(4) doi: 10.3390/nu11040940. PMID: 31027316Free PMC Article
Soluble CD163 is associated with body mass index and blood pressure in hypertensive obese Saudi patients.
Al-Daghri NM, Al-Attas OS, Bindahman LS, Alokail MS, Alkharfy KM, Draz HM, Yakout S, McTernan PG, Sabico S, Chrousos GP
Eur J Clin Invest 2012 Nov;42(11):1221-6. Epub 2012 Sep 4 doi: 10.1111/j.1365-2362.2012.02714.x. PMID: 22946776

Recent systematic reviews

The association of soluble CD163, a novel biomarker of macrophage activation, with type 2 diabetes mellitus and its underlying physiological disorders: A systematic review.
Semnani-Azad Z, Blanco Mejia S, Connelly PW, Bazinet RP, Retnakaran R, Jenkins DJA, Harris SB, Hanley AJ
Obes Rev 2021 Sep;22(9):e13257. Epub 2021 Apr 28 doi: 10.1111/obr.13257. PMID: 33913230

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...