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Radiculitis

MedGen UID:
11099
•Concept ID:
C0034544
•
Disease or Syndrome
Synonyms: Inflammation, Nerve Root; Nerve Root Inflammation; Nerve Root Inflammations; Radiculitides
SNOMED CT: Radiculitis (82473003)
 
Monarch Initiative: MONDO:0021765

Definition

An inflammatory process affecting a nerve root. Patients experience pain radiating along a nerve path because of spinal pressure on the nerve root that connects to the nerve path. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRadiculitis

Professional guidelines

PubMed

Steroid Distancing in Interventional Pain Management During COVID-19 and Beyond: Safe, Effective and Practical Approach.
Manchikanti L, Kosanovic R, Vanaparthy R, Vangala BP, Soin A, Sachdeva H, Shah S, Knezevic NN, Hirsch JA
Pain Physician 2020 Aug;23(4S):S319-S350. PMID: 32942792
Neurostimulation for the treatment of axial back pain: a review of mechanisms, techniques, outcomes, and future advances.
Deer T, Pope J, Hayek S, Narouze S, Patil P, Foreman R, Sharan A, Levy R
Neuromodulation 2014 Oct;17 Suppl 2:52-68. doi: 10.1111/j.1525-1403.2012.00530.x. PMID: 25395117
An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations.
Manchikanti L, Abdi S, Atluri S, Benyamin RM, Boswell MV, Buenaventura RM, Bryce DA, Burks PA, Caraway DL, Calodney AK, Cash KA, Christo PJ, Cohen SP, Colson J, Conn A, Cordner H, Coubarous S, Datta S, Deer TR, Diwan S, Falco FJ, Fellows B, Geffert S, Grider JS, Gupta S, Hameed H, Hameed M, Hansen H, Helm S 2nd, Janata JW, Justiz R, Kaye AD, Lee M, Manchikanti KN, McManus CD, Onyewu O, Parr AT, Patel VB, Racz GB, Sehgal N, Sharma ML, Simopoulos TT, Singh V, Smith HS, Snook LT, Swicegood JR, Vallejo R, Ward SP, Wargo BW, Zhu J, Hirsch JA
Pain Physician 2013 Apr;16(2 Suppl):S49-283. PMID: 23615883

Recent clinical studies

Etiology

Cervical disc degeneration: important considerations for the manual therapist.
Swanson BT, Creighton D
J Man Manip Ther 2022 Jun;30(3):139-153. Epub 2021 Nov 25 doi: 10.1080/10669817.2021.2000089. PMID: 34821212Free PMC Article
Lyme disease.
Chomel B
Rev Sci Tech 2015 Aug;34(2):569-76. doi: 10.20506/rst.34.2.2380. PMID: 26601457
An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations.
Manchikanti L, Abdi S, Atluri S, Benyamin RM, Boswell MV, Buenaventura RM, Bryce DA, Burks PA, Caraway DL, Calodney AK, Cash KA, Christo PJ, Cohen SP, Colson J, Conn A, Cordner H, Coubarous S, Datta S, Deer TR, Diwan S, Falco FJ, Fellows B, Geffert S, Grider JS, Gupta S, Hameed H, Hameed M, Hansen H, Helm S 2nd, Janata JW, Justiz R, Kaye AD, Lee M, Manchikanti KN, McManus CD, Onyewu O, Parr AT, Patel VB, Racz GB, Sehgal N, Sharma ML, Simopoulos TT, Singh V, Smith HS, Snook LT, Swicegood JR, Vallejo R, Ward SP, Wargo BW, Zhu J, Hirsch JA
Pain Physician 2013 Apr;16(2 Suppl):S49-283. PMID: 23615883
Neurotoxocarosis.
Finsterer J, Auer H
Rev Inst Med Trop Sao Paulo 2007 Sep-Oct;49(5):279-87. doi: 10.1590/s0036-46652007000500002. PMID: 18026633
Cervical radiculitis and shoulder disorders.
Manifold SG, McCann PD
Clin Orthop Relat Res 1999 Nov;(368):105-13. PMID: 10613158

Diagnosis

Neurobrucellosis.
Soares CN, da Silva MTT, Lima MA
Curr Opin Infect Dis 2023 Jun 1;36(3):192-197. Epub 2023 Apr 6 doi: 10.1097/QCO.0000000000000920. PMID: 37093043
Neuroborreliosis and Neurosyphilis.
Halperin JJ
Continuum (Minneap Minn) 2018 Oct;24(5, Neuroinfectious Disease):1439-1458. doi: 10.1212/CON.0000000000000645. PMID: 30273247
Lyme disease.
Chomel B
Rev Sci Tech 2015 Aug;34(2):569-76. doi: 10.20506/rst.34.2.2380. PMID: 26601457
Herpes simplex virus.
Widener RW, Whitley RJ
Handb Clin Neurol 2014;123:251-63. doi: 10.1016/B978-0-444-53488-0.00011-0. PMID: 25015489
Lyme neuroborreliosis.
Hansen K, Crone C, Kristoferitsch W
Handb Clin Neurol 2013;115:559-75. doi: 10.1016/B978-0-444-52902-2.00032-1. PMID: 23931802

Therapy

Neurobrucellosis.
Soares CN, da Silva MTT, Lima MA
Curr Opin Infect Dis 2023 Jun 1;36(3):192-197. Epub 2023 Apr 6 doi: 10.1097/QCO.0000000000000920. PMID: 37093043
Complications Associated With Bone Morphogenetic Protein in the Lumbar Spine.
Kang DG, Hsu WK, Lehman RA Jr
Orthopedics 2017 Mar 1;40(2):e229-e237. Epub 2016 Dec 20 doi: 10.3928/01477447-20161213-06. PMID: 27992640
Lyme disease.
Chomel B
Rev Sci Tech 2015 Aug;34(2):569-76. doi: 10.20506/rst.34.2.2380. PMID: 26601457
A systematic evaluation of thoracic interlaminar epidural injections.
Benyamin RM, Wang VC, Vallejo R, Singh V, Helm Ii S
Pain Physician 2012 Jul-Aug;15(4):E497-514. PMID: 22828696
Complications associated with posterior and transforaminal lumbar interbody fusion.
Chrastil J, Patel AA
J Am Acad Orthop Surg 2012 May;20(5):283-91. doi: 10.5435/JAAOS-20-05-283. PMID: 22553100

Prognosis

Postoperative Radiculitis After L5-S1 Anterior Lumbar Interbody Fusion.
Araghi K, Fourman MS, Merrill RK, Maayan O, Zhao E, Pajak A, Subramanian T, Kim DN, Kamil R, Shahi P, Sheha ED, Dowdell JE, Iyer S, Qureshi SA
Spine (Phila Pa 1976) 2023 Sep 15;48(18):1317-1325. Epub 2023 Jun 1 doi: 10.1097/BRS.0000000000004740. PMID: 37259185
Viral infection of the spinal cord and roots.
Yokota H, Yamada K
Neuroimaging Clin N Am 2015 May;25(2):247-58. Epub 2015 Mar 3 doi: 10.1016/j.nic.2015.01.005. PMID: 25952176
Neurotoxocarosis.
Finsterer J, Auer H
Rev Inst Med Trop Sao Paulo 2007 Sep-Oct;49(5):279-87. doi: 10.1590/s0036-46652007000500002. PMID: 18026633
Lyme disease and the heart.
Haddad FA, Nadelman RB
Front Biosci 2003 Sep 1;8:s769-82. doi: 10.2741/1065. PMID: 12957829
Acute brachial radiculitis; course and prognosis.
DIXON GJ, DICK TB
Lancet 1945 Dec 1;2(6380):707. doi: 10.1016/s0140-6736(45)91034-8. PMID: 21007351

Clinical prediction guides

Clinical characteristics of Lyme neuroborreliosis in Dutch children and adults.
van Samkar A, Bruinsma RA, Vermeeren YM, Wieberdink RG, van Bemmel T, Reijer PMD, van Kooten B, Zomer TP
Eur J Pediatr 2023 Mar;182(3):1183-1189. Epub 2023 Jan 6 doi: 10.1007/s00431-022-04749-5. PMID: 36607413
Systematic review of the therapeutic effectiveness of cervical facet joint interventions: an update.
Falco FJ, Manchikanti L, Datta S, Wargo BW, Geffert S, Bryce DA, Atluri S, Singh V, Benyamin RM, Sehgal N, Ward SP, Helm S 2nd, Gupta S, Boswell MV
Pain Physician 2012 Nov-Dec;15(6):E839-68. PMID: 23159978
A systematic evaluation of thoracic interlaminar epidural injections.
Benyamin RM, Wang VC, Vallejo R, Singh V, Helm Ii S
Pain Physician 2012 Jul-Aug;15(4):E497-514. PMID: 22828696
Systematic review of caudal epidural injections in the management of chronic low back pain.
Conn A, Buenaventura RM, Datta S, Abdi S, Diwan S
Pain Physician 2009 Jan-Feb;12(1):109-35. PMID: 19165299
North American Lyme neuroborreliosis.
Halperin JJ
Scand J Infect Dis Suppl 1991;77:74-80. PMID: 1658921

Recent systematic reviews

Systematic Review of the Diagnostic Accuracy and Therapeutic Effectiveness of Sacroiliac Joint Interventions.
Simopoulos TT, Manchikanti L, Gupta S, Aydin SM, Kim CH, Solanki D, Nampiaparampil DE, Singh V, Staats PS, Hirsch JA
Pain Physician 2015 Sep-Oct;18(5):E713-56. PMID: 26431129
Complications associated with the use of the recombinant human bone morphogenetic proteins for posterior interbody fusions of the lumbar spine.
Chrastil J, Low JB, Whang PG, Patel AA
Spine (Phila Pa 1976) 2013 Jul 15;38(16):E1020-7. doi: 10.1097/BRS.0b013e3182982f8e. PMID: 23629484
Systematic review of the therapeutic effectiveness of cervical facet joint interventions: an update.
Falco FJ, Manchikanti L, Datta S, Wargo BW, Geffert S, Bryce DA, Atluri S, Singh V, Benyamin RM, Sehgal N, Ward SP, Helm S 2nd, Gupta S, Boswell MV
Pain Physician 2012 Nov-Dec;15(6):E839-68. PMID: 23159978
A systematic evaluation of thoracic interlaminar epidural injections.
Benyamin RM, Wang VC, Vallejo R, Singh V, Helm Ii S
Pain Physician 2012 Jul-Aug;15(4):E497-514. PMID: 22828696
Systematic review of caudal epidural injections in the management of chronic low back pain.
Conn A, Buenaventura RM, Datta S, Abdi S, Diwan S
Pain Physician 2009 Jan-Feb;12(1):109-35. PMID: 19165299

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