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Kidney fibrosarcoma

MedGen UID:
116050
•Concept ID:
C0238208
•
Neoplastic Process
Synonyms: Fibrosarcoma of Kidney; fibrosarcoma of kidney; Fibrosarcoma of the Kidney; fibrosarcoma of the kidney; Kidney Fibrosarcoma; kidney fibrosarcoma; kidney fibrosarcoma (disease); Renal Fibrosarcoma; renal fibrosarcoma
 
Monarch Initiative: MONDO:0003720

Definition

A usually aggressive malignant neoplasm arising from the kidney. It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVKidney fibrosarcoma

Professional guidelines

PubMed

Diagnosis and treatment of primary adult renal sarcoma.
Huang ZM, Li HZ, Ji ZG, Shi BB
Chin Med Sci J 2011 Sep;26(3):172-4. doi: 10.1016/s1001-9294(11)60044-8. PMID: 22207927
Mesenchymal stem cells as a gene therapy carrier for treatment of fibrosarcoma.
Xiang J, Tang J, Song C, Yang Z, Hirst DG, Zheng QJ, Li G
Cytotherapy 2009;11(5):516-26. doi: 10.1080/14653240902960429. PMID: 19562576
Diagnostic histopathologic criteria in pediatric tumors: an eclectic review.
Wakely PE Jr, Favara BE, Galliani CA
Crit Rev Oncol Hematol 1986;6(3):261-86. doi: 10.1016/s1040-8428(86)80058-0. PMID: 3026670

Recent clinical studies

Diagnosis

Perivascular epithelioid cell tumor (PEComa) of the kidney: an overview of its management and outcomes.
Yang Y, Yu X, Lu B, Shao Z
J Int Med Res 2020 Oct;48(10):300060520961223. doi: 10.1177/0300060520961223. PMID: 33070694Free PMC Article

Therapy

Sodium butyrate alters erythropoietin glycosylation via multiple mechanisms.
Crowell CK, Qin Q, Grampp GE, Radcliffe RA, Rogers GN, Scheinman RI
Biotechnol Bioeng 2008 Jan 1;99(1):201-13. doi: 10.1002/bit.21539. PMID: 17570711

Prognosis

Sodium butyrate alters erythropoietin glycosylation via multiple mechanisms.
Crowell CK, Qin Q, Grampp GE, Radcliffe RA, Rogers GN, Scheinman RI
Biotechnol Bioeng 2008 Jan 1;99(1):201-13. doi: 10.1002/bit.21539. PMID: 17570711

Clinical prediction guides

Sodium butyrate alters erythropoietin glycosylation via multiple mechanisms.
Crowell CK, Qin Q, Grampp GE, Radcliffe RA, Rogers GN, Scheinman RI
Biotechnol Bioeng 2008 Jan 1;99(1):201-13. doi: 10.1002/bit.21539. PMID: 17570711
Growth and transformation suppressor genes for BHK Syrian hamster cells on human chromosomes 1 and 11.
Annab LA, Dong JT, Futreal PA, Satoh H, Oshimura M, Barrett JC
Mol Carcinog 1992;6(4):280-8. doi: 10.1002/mc.2940060410. PMID: 1485918

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