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Metastatic Carcinoma in the Uterine Cervix

MedGen UID:
124478
Concept ID:
C0278584
Neoplastic Process
Synonyms: Metastatic Carcinoma to the Cervix; Metastatic Carcinoma to the Cervix Uteri; Metastatic Carcinoma to the Uterine Cervix; Secondary Carcinoma to the Cervix; Secondary Carcinoma to the Cervix Uteri; Secondary Carcinoma to the Uterine Cervix

Definition

A carcinoma that has spread to the cervix from another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Carcinoma in the Uterine Cervix

Professional guidelines

PubMed

Kumar L, Gupta S
Oncology 2016;91 Suppl 1:8-17. Epub 2016 Jul 28 doi: 10.1159/000447576. PMID: 27464068
FIGO Committee on Gynecologic Oncology
Int J Gynaecol Obstet 2014 May;125(2):97-8. Epub 2014 Feb 22 doi: 10.1016/j.ijgo.2014.02.003. PMID: 24630859
Mountzios G, Soultati A, Pectasides D, Pectasides E, Dimopoulos MA, Papadimitriou CA
Cancer Treat Rev 2013 Aug;39(5):430-43. Epub 2012 Jun 22 doi: 10.1016/j.ctrv.2012.05.009. PMID: 22727690

Recent clinical studies

Etiology

Schmeler KM, Pareja R, Lopez Blanco A, Humberto Fregnani J, Lopes A, Perrotta M, Tsunoda AT, Cantú-de-León DF, Ramondetta LM, Manchana T, Crotzer DR, McNally OM, Riege M, Scambia G, Carvajal JM, Di Guilmi J, Rendon GJ, Ramalingam P, Fellman BM, Coleman RL, Frumovitz M, Ramirez PT
Int J Gynecol Cancer 2021 Oct;31(10):1317-1325. Epub 2021 Sep 7 doi: 10.1136/ijgc-2021-002921. PMID: 34493587
Pors J, Segura S, Chiu DS, Almadani N, Ren H, Fix DJ, Howitt BE, Kolin D, McCluggage WG, Mirkovic J, Gilks B, Park KJ, Hoang L
Am J Surg Pathol 2021 Apr 1;45(4):498-506. doi: 10.1097/PAS.0000000000001612. PMID: 33165093Free PMC Article
Obermair A, Asher R, Pareja R, Frumovitz M, Lopez A, Moretti-Marques R, Rendon G, Ribeiro R, Tsunoda A, Behan V, Buda A, Bernadini MQ, Zhao H, Vieira M, Walker J, Spirtos NM, Yao S, Chetty N, Zhu T, Isla D, Tamura M, Nicklin J, Robledo KP, Gebski V, Coleman RL, Salvo G, Ramirez PT
Am J Obstet Gynecol 2020 Mar;222(3):249.e1-249.e10. Epub 2019 Oct 3 doi: 10.1016/j.ajog.2019.09.036. PMID: 31586602Free PMC Article
Bhatla N, Berek JS, Cuello Fredes M, Denny LA, Grenman S, Karunaratne K, Kehoe ST, Konishi I, Olawaiye AB, Prat J, Sankaranarayanan R, Brierley J, Mutch D, Querleu D, Cibula D, Quinn M, Botha H, Sigurd L, Rice L, Ryu HS, Ngan H, Mäenpää J, Andrijono A, Purwoto G, Maheshwari A, Bafna UD, Plante M, Natarajan J
Int J Gynaecol Obstet 2019 Apr;145(1):129-135. Epub 2019 Jan 17 doi: 10.1002/ijgo.12749. PMID: 30656645
Pérez-Montiel D, Serrano-Olvera A, Salazar LC, Cetina-Pérez L, Candelaria M, Coronel J, Montalvo LA, de León DC
J Obstet Gynaecol Res 2012 Mar;38(3):541-9. Epub 2012 Feb 22 doi: 10.1111/j.1447-0756.2011.01747.x. PMID: 22353422

Diagnosis

Lee JE, Chung Y, Rhee S, Kim TH
BMB Rep 2022 Sep;55(9):429-438. doi: 10.5483/BMBRep.2022.55.9.042. PMID: 35725012Free PMC Article
Rivera-Colón G, Zheng W
Semin Diagn Pathol 2022 May;39(3):213-227. Epub 2021 Dec 18 doi: 10.1053/j.semdp.2021.12.002. PMID: 34953647
Schmeler KM, Pareja R, Lopez Blanco A, Humberto Fregnani J, Lopes A, Perrotta M, Tsunoda AT, Cantú-de-León DF, Ramondetta LM, Manchana T, Crotzer DR, McNally OM, Riege M, Scambia G, Carvajal JM, Di Guilmi J, Rendon GJ, Ramalingam P, Fellman BM, Coleman RL, Frumovitz M, Ramirez PT
Int J Gynecol Cancer 2021 Oct;31(10):1317-1325. Epub 2021 Sep 7 doi: 10.1136/ijgc-2021-002921. PMID: 34493587
Loureiro J, Oliva E
Arch Pathol Lab Med 2014 Apr;138(4):453-83. doi: 10.5858/arpa.2012-0493-RA. PMID: 24678677
Pérez-Montiel D, Serrano-Olvera A, Salazar LC, Cetina-Pérez L, Candelaria M, Coronel J, Montalvo LA, de León DC
J Obstet Gynaecol Res 2012 Mar;38(3):541-9. Epub 2012 Feb 22 doi: 10.1111/j.1447-0756.2011.01747.x. PMID: 22353422

Therapy

Mileshkin LR, Moore KN, Barnes EH, Gebski V, Narayan K, King MT, Bradshaw N, Lee YC, Diamante K, Fyles AW, Small W Jr, Gaffney DK, Khaw P, Brooks S, Thompson JS, Huh WK, Mathews CA, Buck M, Suder A, Lad TE, Barani IJ, Holschneider CH, Van Dyk S, Quinn M, Rischin D, Monk BJ, Stockler MR
Lancet Oncol 2023 May;24(5):468-482. Epub 2023 Apr 17 doi: 10.1016/S1470-2045(23)00147-X. PMID: 37080223Free PMC Article
Bose CK
Med Oncol 2022 Jan 29;39(4):47. doi: 10.1007/s12032-022-01646-7. PMID: 35092506
Obermair A, Asher R, Pareja R, Frumovitz M, Lopez A, Moretti-Marques R, Rendon G, Ribeiro R, Tsunoda A, Behan V, Buda A, Bernadini MQ, Zhao H, Vieira M, Walker J, Spirtos NM, Yao S, Chetty N, Zhu T, Isla D, Tamura M, Nicklin J, Robledo KP, Gebski V, Coleman RL, Salvo G, Ramirez PT
Am J Obstet Gynecol 2020 Mar;222(3):249.e1-249.e10. Epub 2019 Oct 3 doi: 10.1016/j.ajog.2019.09.036. PMID: 31586602Free PMC Article
Fujiwara K, Monk B, Devouassoux-Shisheboran M
Curr Oncol Rep 2014 Dec;16(12):416. doi: 10.1007/s11912-014-0416-y. PMID: 25325935
IARC Monogr Eval Carcinog Risk Chem Hum 1979 Dec;21:417-29. PMID: 120837

Prognosis

Rivera-Colón G, Zheng W
Semin Diagn Pathol 2022 May;39(3):213-227. Epub 2021 Dec 18 doi: 10.1053/j.semdp.2021.12.002. PMID: 34953647
Fujiwara K, Monk B, Devouassoux-Shisheboran M
Curr Oncol Rep 2014 Dec;16(12):416. doi: 10.1007/s11912-014-0416-y. PMID: 25325935
Guitarte C, Alagkiozidis I, Mize B, Stevens E, Salame G, Lee YC
Gynecol Oncol 2014 May;133(2):186-91. Epub 2014 Feb 4 doi: 10.1016/j.ygyno.2014.01.048. PMID: 24503463
Mountzios G, Soultati A, Pectasides D, Pectasides E, Dimopoulos MA, Papadimitriou CA
Cancer Treat Rev 2013 Aug;39(5):430-43. Epub 2012 Jun 22 doi: 10.1016/j.ctrv.2012.05.009. PMID: 22727690
Pérez-Montiel D, Serrano-Olvera A, Salazar LC, Cetina-Pérez L, Candelaria M, Coronel J, Montalvo LA, de León DC
J Obstet Gynaecol Res 2012 Mar;38(3):541-9. Epub 2012 Feb 22 doi: 10.1111/j.1447-0756.2011.01747.x. PMID: 22353422

Clinical prediction guides

Tewari KS, Colombo N, Monk BJ, Dubot C, Cáceres MV, Hasegawa K, Shapira-Frommer R, Salman P, Yañez E, Gümüs M, Olivera Hurtado de Mendoza M, Samouëlian V, Castonguay V, Arkhipov A, Tekin C, Li K, Toker S, Keefe SM, Lorusso D
JAMA Oncol 2024 Feb 1;10(2):185-192. doi: 10.1001/jamaoncol.2023.5410. PMID: 38095881Free PMC Article
Rivera-Colón G, Zheng W
Semin Diagn Pathol 2022 May;39(3):213-227. Epub 2021 Dec 18 doi: 10.1053/j.semdp.2021.12.002. PMID: 34953647
Yordanov A, Karamanliev M, Tantchev L, Konsoulova A, Strashilov S, Vasileva-Slaveva M
Medicina (Kaunas) 2020 Jan 18;56(1) doi: 10.3390/medicina56010037. PMID: 31963763Free PMC Article
Groves IJ, Coleman N
J Pathol 2015 Mar;235(4):527-38. Epub 2015 Jan 20 doi: 10.1002/path.4496. PMID: 25604863
Mountzios G, Soultati A, Pectasides D, Pectasides E, Dimopoulos MA, Papadimitriou CA
Cancer Treat Rev 2013 Aug;39(5):430-43. Epub 2012 Jun 22 doi: 10.1016/j.ctrv.2012.05.009. PMID: 22727690

Recent systematic reviews

Gadducci A, Carinelli S, Aletti G
Gynecol Oncol 2017 Mar;144(3):637-646. Epub 2017 Jan 3 doi: 10.1016/j.ygyno.2016.12.003. PMID: 28057354
Jiao XB, Hu J, Zhu LR
Int J Gynecol Cancer 2016 Oct;26(8):1510-4. doi: 10.1097/IGC.0000000000000780. PMID: 27465895
Savone D, Carrone A, Riganelli L, Merlino L, Mancino P, Benedetti Panici P
Tumori 2016 Oct 13;102(5):450-458. Epub 2016 Jul 18 doi: 10.5301/tj.5000524. PMID: 27443891
Guitarte C, Alagkiozidis I, Mize B, Stevens E, Salame G, Lee YC
Gynecol Oncol 2014 May;133(2):186-91. Epub 2014 Feb 4 doi: 10.1016/j.ygyno.2014.01.048. PMID: 24503463
Pérez-Montiel D, Serrano-Olvera A, Salazar LC, Cetina-Pérez L, Candelaria M, Coronel J, Montalvo LA, de León DC
J Obstet Gynaecol Res 2012 Mar;38(3):541-9. Epub 2012 Feb 22 doi: 10.1111/j.1447-0756.2011.01747.x. PMID: 22353422

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