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Floor of Mouth Adenoid Cystic Carcinoma

MedGen UID:
124719
•Concept ID:
C0280312
•
Neoplastic Process
Synonyms: Adenoid Cystic Carcinoma of Floor of Mouth; Adenoid Cystic Carcinoma of the Floor of Mouth

Definition

An adenoid cystic carcinoma of the oral cavity that arises from the floor of the mouth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFloor of Mouth Adenoid Cystic Carcinoma

Professional guidelines

PubMed

The treatment of sublingual gland tumours.
Sun G, Yang X, Tang E, Wen J, Lu M, Hu Q
Int J Oral Maxillofac Surg 2010 Sep;39(9):863-8. doi: 10.1016/j.ijom.2010.04.051. PMID: 20605409
Management of adenoid cystic carcinoma of minor salivary glands.
Triantafillidou K, Dimitrakopoulos J, Iordanidis F, Koufogiannis D
J Oral Maxillofac Surg 2006 Jul;64(7):1114-20. doi: 10.1016/j.joms.2005.06.017. PMID: 16781345
Management of malignant sublingual salivary gland tumors.
Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A
Oral Oncol 2004 Jan;40(1):2-5. doi: 10.1016/s1368-8375(03)00104-0. PMID: 14662408

Recent clinical studies

Etiology

Salivary gland adenoid cystic carcinoma with cervical lymph node metastasis: a preliminary study of 62 cases.
Min R, Siyi L, Wenjun Y, Ow A, Lizheng W, Minjun D, Chenping Z
Int J Oral Maxillofac Surg 2012 Aug;41(8):952-7. Epub 2012 May 28 doi: 10.1016/j.ijom.2012.04.023. PMID: 22647764
Multiple malignant salivary gland neoplasms: mucoepidermoid carcinoma of palate and adenoid cystic carcinoma of floor of mouth.
Whitt JC, Schafer DR, Callihan MD
Head Neck Pathol 2008 Mar;2(1):41-8. Epub 2007 Dec 6 doi: 10.1007/s12105-007-0026-1. PMID: 20614341Free PMC Article
Management of adenoid cystic carcinoma of minor salivary glands.
Triantafillidou K, Dimitrakopoulos J, Iordanidis F, Koufogiannis D
J Oral Maxillofac Surg 2006 Jul;64(7):1114-20. doi: 10.1016/j.joms.2005.06.017. PMID: 16781345
Masses of the tongue and floor of the mouth: findings on magnetic resonance imaging.
Ozturk M, Yorulmaz I, Guney E, Ozcan N
Eur Radiol 2000;10(10):1669-74. doi: 10.1007/s003300000475. PMID: 11044946
Radiographic evaluation of bone invasion of adenoid cystic carcinoma in the oral and maxillofacial region.
Suei Y, Tanimoto K, Taguchi A, Wada T
J Oral Maxillofac Surg 1994 Aug;52(8):821-6. doi: 10.1016/0278-2391(94)90227-5. PMID: 8040735

Diagnosis

Adenoid cystic carcinoma with dedifferentiation/expansion of the luminal cell component and preserved biphasic morphology - Early high-grade transformation.
Chia N, Petersson F
Ann Diagn Pathol 2021 Feb;50:151650. Epub 2020 Oct 24 doi: 10.1016/j.anndiagpath.2020.151650. PMID: 33254086
Management of malignant sublingual salivary gland tumors.
Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A
Oral Oncol 2004 Jan;40(1):2-5. doi: 10.1016/s1368-8375(03)00104-0. PMID: 14662408
Malignant tumors of the oral cavity and oropharynx: clinical, pathologic, and radiologic evaluation.
Weber AL, Romo L, Hashmi S
Neuroimaging Clin N Am 2003 Aug;13(3):443-64. doi: 10.1016/s1052-5149(03)00037-6. PMID: 14631684
Intraoral and transoral fine needle aspiration. A review of 25 cases.
Cramer H, Lampe H, Downing P
Acta Cytol 1995 Jul-Aug;39(4):683-8. PMID: 7543234
Salivary glands.
Saunders JR Jr, Hirata RM, Jaques DA
Surg Clin North Am 1986 Feb;66(1):59-81. doi: 10.1016/s0039-6109(16)43829-6. PMID: 3003940

Therapy

Effect of a nitric oxide synthase inhibitor and a CXC chemokine receptor-4 antagonist on tumor growth and metastasis in a xenotransplanted mouse model of adenoid cystic carcinoma of the oral floor.
Takaoka K, Hidaka S, Hashitani S, Segawa E, Yamamura M, Tanaka N, Zushi Y, Noguchi K, Kishimoto H, Urade M
Int J Oncol 2013 Sep;43(3):737-45. Epub 2013 Jul 8 doi: 10.3892/ijo.2013.2011. PMID: 23835861
Autonomization of free flaps in the oral cavity: A prospective clinical study.
Mücke T, Wolff KD, Rau A, Kehl V, Mitchell DA, Steiner T
Microsurgery 2012 Mar;32(3):201-6. Epub 2012 Jan 20 doi: 10.1002/micr.20984. PMID: 22262645
Persistent and/or late complications of combined radiation therapy and hyperthermia.
Ben-Yosef R, Kapp DS
Int J Hyperthermia 1992 Nov-Dec;8(6):733-45. doi: 10.3109/02656739209005021. PMID: 1479199
Photoradiation therapy of head and neck cancer.
Wile AG, Novotny J, Mason GR, Passy V, Berns MW
Prog Clin Biol Res 1984;170:681-91. PMID: 6099573

Prognosis

Malignant pleural effusion and pericardial effusion, an unusual presentation of metastatic adenoid cystic carcinoma of the floor of mouth: A case report with cyto-histopathological correlation.
Lin C, Nandakumar L
Diagn Cytopathol 2023 Nov;51(11):E317-E321. Epub 2023 Aug 6 doi: 10.1002/dc.25210. PMID: 37545254
The role of elective neck dissection in patients with adenoid cystic carcinoma of the head and neck.
Xiao R, Sethi RKV, Feng AL, Fontanarosa JB, Deschler DG
Laryngoscope 2019 Sep;129(9):2094-2104. Epub 2019 Jan 22 doi: 10.1002/lary.27814. PMID: 30667061
Management of adenoid cystic carcinoma of minor salivary glands.
Triantafillidou K, Dimitrakopoulos J, Iordanidis F, Koufogiannis D
J Oral Maxillofac Surg 2006 Jul;64(7):1114-20. doi: 10.1016/j.joms.2005.06.017. PMID: 16781345
Management of malignant sublingual salivary gland tumors.
Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A
Oral Oncol 2004 Jan;40(1):2-5. doi: 10.1016/s1368-8375(03)00104-0. PMID: 14662408
Malignant tumors of the oral cavity and oropharynx: clinical, pathologic, and radiologic evaluation.
Weber AL, Romo L, Hashmi S
Neuroimaging Clin N Am 2003 Aug;13(3):443-64. doi: 10.1016/s1052-5149(03)00037-6. PMID: 14631684

Clinical prediction guides

The role of elective neck dissection in patients with adenoid cystic carcinoma of the head and neck.
Xiao R, Sethi RKV, Feng AL, Fontanarosa JB, Deschler DG
Laryngoscope 2019 Sep;129(9):2094-2104. Epub 2019 Jan 22 doi: 10.1002/lary.27814. PMID: 30667061
A case of sublingual adenoid cystic carcinoma involving the mandible presenting as a "skip lesion".
Fujita M, Yanagi Y, Cortes ARG, Arita ES, Onoda T, Nagatsuka H, Asaumi JI
Oral Radiol 2018 Sep;34(3):281-287. Epub 2017 Nov 27 doi: 10.1007/s11282-017-0306-8. PMID: 30484035
Salivary gland adenoid cystic carcinoma with cervical lymph node metastasis: a preliminary study of 62 cases.
Min R, Siyi L, Wenjun Y, Ow A, Lizheng W, Minjun D, Chenping Z
Int J Oral Maxillofac Surg 2012 Aug;41(8):952-7. Epub 2012 May 28 doi: 10.1016/j.ijom.2012.04.023. PMID: 22647764
Radiographic evaluation of bone invasion of adenoid cystic carcinoma in the oral and maxillofacial region.
Suei Y, Tanimoto K, Taguchi A, Wada T
J Oral Maxillofac Surg 1994 Aug;52(8):821-6. doi: 10.1016/0278-2391(94)90227-5. PMID: 8040735
Persistent and/or late complications of combined radiation therapy and hyperthermia.
Ben-Yosef R, Kapp DS
Int J Hyperthermia 1992 Nov-Dec;8(6):733-45. doi: 10.3109/02656739209005021. PMID: 1479199

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