Acute necrosis of liver

MedGen UID:: 1320
•Concept ID:: C0001364
•: Pathologic Function

Synonyms:	Acute Yellow Atrophies; Acute Yellow Atrophy; Acute Yellow Atrophy of Liver; Hepatic Necrosis, Massive; Massive Hepatic Necrosis; Yellow Atrophy, Acute
SNOMED CT:	Acute necrosis of liver (197269008); Massive hepatic necrosis (197269008)

Definition

Extensive and rapid death of parenchymal cells in the LIVER, often due to exposure to toxic materials or drug-induced injury. It is characterized by a soft, flabby, yellow-brown wrinkled, and shrunken liver. It was called ""acute yellow atrophy"". [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAcute necrosis of liver

Abnormality of the digestive system
- Abnormality of digestive system physiology
  - Abnormality of hepatobiliary system physiology
    - Decreased liver function
      - Liver failure
        Acute liver failure
        Acute necrosis of liver

Professional guidelines

PubMed

Diagnosis and management of autoimmune hepatitis.

Muratori L, Lohse AW, Lenzi M
BMJ 2023 Feb 6;380:e070201. doi: 10.1136/bmj-2022-070201. PMID: 36746473

Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium.

Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224

The knowns and unknowns of treatment for alcoholic hepatitis.

Sehrawat TS, Liu M, Shah VH
Lancet Gastroenterol Hepatol 2020 May;5(5):494-506. doi: 10.1016/S2468-1253(19)30326-7. PMID: 32277902 Free PMC Article

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