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Euthyroid Condition

MedGen UID:
1372825
•Concept ID:
C4329801
•
Disease or Syndrome

Definition

Derangement of the thyroid gland or thyroid hormone metabolism that is unaccompanied by signs or symptoms of hypothyroidism or hyperthyroidism. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEuthyroid Condition

Professional guidelines

PubMed

Immunologic and hormonal effects of prophylthiouracil treatment using maintenance dose in Graves' disease patients.
Decroli E, Manaf A, Syahbuddin S
Acta Med Indones 2014 Oct;46(4):314-9. PMID: 25633548
Evaluation of the patients with Grave's ophthalmopathy after the corticosteroids treatment.
Petrović MJ, Sarenac T, Srećković S, Petrović M, Vulović D, Janićijević K
Vojnosanit Pregl 2012 Mar;69(3):249-52. PMID: 22624411
Is the anteroposterior and transverse diameter ratio of nonpalpable thyroid nodules a sonographic criteria for recommending fine-needle aspiration cytology?
Cappelli C, Pirola I, Cumetti D, Micheletti L, Tironi A, Gandossi E, Martino E, Cherubini L, Agosti B, Castellano M, Mattanza C, Rosei EA
Clin Endocrinol (Oxf) 2005 Dec;63(6):689-93. doi: 10.1111/j.1365-2265.2005.02406.x. PMID: 16343105

Recent clinical studies

Etiology

Subclinical Hypothyroidism in Patients with Obesity and Metabolic Syndrome: A Narrative Review.
Biondi B
Nutrients 2023 Dec 27;16(1) doi: 10.3390/nu16010087. PMID: 38201918Free PMC Article
Household Iodized Salt, Iodine Intake, and Thyroid Dysfunction in Reproductive Age Women in Different Regions of Iodine Adequacy.
Kumorowulan S, Nurcahyani YD, Latifah L
J Nutr Sci Vitaminol (Tokyo) 2020;66(Supplement):S468-S473. doi: 10.3177/jnsv.66.S468. PMID: 33612643
Thyroid function related symptoms during levothyroxine monotherapy in athyreotic patients.
Ito M, Miyauchi A, Hisakado M, Yoshioka W, Kudo T, Nishihara E, Kihara M, Ito Y, Miya A, Fukata S, Nishikawa M, Nakamura H
Endocr J 2019 Nov 28;66(11):953-960. Epub 2019 Jul 2 doi: 10.1507/endocrj.EJ19-0094. PMID: 31270299
Biochemical Markers Reflecting Thyroid Function in Athyreotic Patients on Levothyroxine Monotherapy.
Ito M, Miyauchi A, Hisakado M, Yoshioka W, Ide A, Kudo T, Nishihara E, Kihara M, Ito Y, Kobayashi K, Miya A, Fukata S, Nishikawa M, Nakamura H, Amino N
Thyroid 2017 Apr;27(4):484-490. Epub 2017 Feb 6 doi: 10.1089/thy.2016.0426. PMID: 28056660Free PMC Article
Cerebral accumulation of Tc-99m ethyl cysteinate dimer (ECD) in severe, transient hypothyroidism.
Schraml FV, Beason-Held LL, Fletcher DW, Brown BP
J Cereb Blood Flow Metab 2006 Mar;26(3):321-9. doi: 10.1038/sj.jcbfm.9600191. PMID: 16079789

Diagnosis

Subclinical Hypothyroidism in Patients with Obesity and Metabolic Syndrome: A Narrative Review.
Biondi B
Nutrients 2023 Dec 27;16(1) doi: 10.3390/nu16010087. PMID: 38201918Free PMC Article
The Differential Effects of Propylthiouracil and Methimazole as Graves' Disease Treatment on Vascular Atherosclerosis Markers: A Randomized Clinical Trial.
Wisnu W, Alwi I, Nafrialdi N, Harimurti K, Pemayun TGD, Jusman SWA, Santoso DIS, Harahap AR, Suwarto S, Subekti I
Front Endocrinol (Lausanne) 2021;12:796194. Epub 2021 Dec 20 doi: 10.3389/fendo.2021.796194. PMID: 34987480Free PMC Article
Household Iodized Salt, Iodine Intake, and Thyroid Dysfunction in Reproductive Age Women in Different Regions of Iodine Adequacy.
Kumorowulan S, Nurcahyani YD, Latifah L
J Nutr Sci Vitaminol (Tokyo) 2020;66(Supplement):S468-S473. doi: 10.3177/jnsv.66.S468. PMID: 33612643
Cerebral accumulation of Tc-99m ethyl cysteinate dimer (ECD) in severe, transient hypothyroidism.
Schraml FV, Beason-Held LL, Fletcher DW, Brown BP
J Cereb Blood Flow Metab 2006 Mar;26(3):321-9. doi: 10.1038/sj.jcbfm.9600191. PMID: 16079789
Cerebral embolism and hyperthyroidism.
Sato Y, Sato Y, Kakisako S, Honda Y, Kaji M
Kurume Med J 1989;36(1):23-7. doi: 10.2739/kurumemedj.36.23. PMID: 2770220

Therapy

Subclinical Hypothyroidism in Patients with Obesity and Metabolic Syndrome: A Narrative Review.
Biondi B
Nutrients 2023 Dec 27;16(1) doi: 10.3390/nu16010087. PMID: 38201918Free PMC Article
In patients with type 2 diabetes the presence of Hashimoto's thyroiditis reduces the beneficial effect of dipeptidyl peptidase-4 inhibitor on plasma glucose control.
Watanabe T, Temma Y, Okada J, Yamada E, Saito T, Osaki A, Shimda Y, Matsumoto S, Horiguchi K, Ishida E, Kondo Y, Okada K, Takamizawa T, Nakajima Y, Ozawa A, Okada S, Horigome M, Yamada M
Endocr J 2021 May 28;68(5):599-603. Epub 2021 Jan 7 doi: 10.1507/endocrj.EJ20-0620. PMID: 33408313
Thyroid function related symptoms during levothyroxine monotherapy in athyreotic patients.
Ito M, Miyauchi A, Hisakado M, Yoshioka W, Kudo T, Nishihara E, Kihara M, Ito Y, Miya A, Fukata S, Nishikawa M, Nakamura H
Endocr J 2019 Nov 28;66(11):953-960. Epub 2019 Jul 2 doi: 10.1507/endocrj.EJ19-0094. PMID: 31270299
Biochemical Markers Reflecting Thyroid Function in Athyreotic Patients on Levothyroxine Monotherapy.
Ito M, Miyauchi A, Hisakado M, Yoshioka W, Ide A, Kudo T, Nishihara E, Kihara M, Ito Y, Kobayashi K, Miya A, Fukata S, Nishikawa M, Nakamura H, Amino N
Thyroid 2017 Apr;27(4):484-490. Epub 2017 Feb 6 doi: 10.1089/thy.2016.0426. PMID: 28056660Free PMC Article
Mild Thyrotoxicosis Leads to Brain Perfusion Changes: An Arterial Spin Labelling Study.
Göbel A, Heldmann M, Sartorius A, Göttlich M, Dirk AL, Brabant G, Münte TF
J Neuroendocrinol 2017 Jan;29(1) doi: 10.1111/jne.12446. PMID: 27859916

Prognosis

Secondary hormonal alterations in short-term severe hypothyroidism; in the focus: Apelin and copeptin.
Gergics M, Pham-Dobor G, Horváth-Szalai Z, Kőszegi T, Mezősi E, Bajnok L
Front Endocrinol (Lausanne) 2022;13:981891. Epub 2022 Sep 14 doi: 10.3389/fendo.2022.981891. PMID: 36187132Free PMC Article
The Differential Effects of Propylthiouracil and Methimazole as Graves' Disease Treatment on Vascular Atherosclerosis Markers: A Randomized Clinical Trial.
Wisnu W, Alwi I, Nafrialdi N, Harimurti K, Pemayun TGD, Jusman SWA, Santoso DIS, Harahap AR, Suwarto S, Subekti I
Front Endocrinol (Lausanne) 2021;12:796194. Epub 2021 Dec 20 doi: 10.3389/fendo.2021.796194. PMID: 34987480Free PMC Article
In patients with type 2 diabetes the presence of Hashimoto's thyroiditis reduces the beneficial effect of dipeptidyl peptidase-4 inhibitor on plasma glucose control.
Watanabe T, Temma Y, Okada J, Yamada E, Saito T, Osaki A, Shimda Y, Matsumoto S, Horiguchi K, Ishida E, Kondo Y, Okada K, Takamizawa T, Nakajima Y, Ozawa A, Okada S, Horigome M, Yamada M
Endocr J 2021 May 28;68(5):599-603. Epub 2021 Jan 7 doi: 10.1507/endocrj.EJ20-0620. PMID: 33408313
Single-session radiofrequency ablation on benign thyroid nodules: a prospective single center study : Radiofrequency ablation on thyroid.
Aysan E, Idiz UO, Akbulut H, Elmas L
Langenbecks Arch Surg 2016 May;401(3):357-63. Epub 2016 Mar 25 doi: 10.1007/s00423-016-1408-1. PMID: 27013327
Cerebral accumulation of Tc-99m ethyl cysteinate dimer (ECD) in severe, transient hypothyroidism.
Schraml FV, Beason-Held LL, Fletcher DW, Brown BP
J Cereb Blood Flow Metab 2006 Mar;26(3):321-9. doi: 10.1038/sj.jcbfm.9600191. PMID: 16079789

Clinical prediction guides

Subclinical Hypothyroidism in Patients with Obesity and Metabolic Syndrome: A Narrative Review.
Biondi B
Nutrients 2023 Dec 27;16(1) doi: 10.3390/nu16010087. PMID: 38201918Free PMC Article
Secondary hormonal alterations in short-term severe hypothyroidism; in the focus: Apelin and copeptin.
Gergics M, Pham-Dobor G, Horváth-Szalai Z, Kőszegi T, Mezősi E, Bajnok L
Front Endocrinol (Lausanne) 2022;13:981891. Epub 2022 Sep 14 doi: 10.3389/fendo.2022.981891. PMID: 36187132Free PMC Article
The Differential Effects of Propylthiouracil and Methimazole as Graves' Disease Treatment on Vascular Atherosclerosis Markers: A Randomized Clinical Trial.
Wisnu W, Alwi I, Nafrialdi N, Harimurti K, Pemayun TGD, Jusman SWA, Santoso DIS, Harahap AR, Suwarto S, Subekti I
Front Endocrinol (Lausanne) 2021;12:796194. Epub 2021 Dec 20 doi: 10.3389/fendo.2021.796194. PMID: 34987480Free PMC Article
In patients with type 2 diabetes the presence of Hashimoto's thyroiditis reduces the beneficial effect of dipeptidyl peptidase-4 inhibitor on plasma glucose control.
Watanabe T, Temma Y, Okada J, Yamada E, Saito T, Osaki A, Shimda Y, Matsumoto S, Horiguchi K, Ishida E, Kondo Y, Okada K, Takamizawa T, Nakajima Y, Ozawa A, Okada S, Horigome M, Yamada M
Endocr J 2021 May 28;68(5):599-603. Epub 2021 Jan 7 doi: 10.1507/endocrj.EJ20-0620. PMID: 33408313
Cerebral embolism and hyperthyroidism.
Sato Y, Sato Y, Kakisako S, Honda Y, Kaji M
Kurume Med J 1989;36(1):23-7. doi: 10.2739/kurumemedj.36.23. PMID: 2770220

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