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Multiple biliary hamartomas

MedGen UID:
1373951
•Concept ID:
C4316799
•
Neoplastic Process
Synonyms: Biliary hamartoma; Multiple bile duct hamartomas; Von Meyenburg complexes
 
HPO: HP:0025519

Definition

Multiple biliary hamartomas are a rare clinicopathologic entity, consisting of small (less than 1.5cm), usually multiple and nodular cystic lesions in the liver. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultiple biliary hamartomas

Professional guidelines

PubMed

MR imaging features of multiple biliary hamartomas (Von Meyenburg Complex): A pictorial review and differential diagnosis.
Boraschi P, Scalise P, Tarantini G, Colombatto P, Donati F
J Med Imaging Radiat Oncol 2021 Jun;65(3):323-330. Epub 2021 Mar 25 doi: 10.1111/1754-9485.13173. PMID: 33768689

Recent clinical studies

Etiology

A study of multiple biliary hamartomas based on 1697 liver biopsies.
Lin S, Weng Z, Xu J, Wang MF, Zhu YY, Jiang JJ
Eur J Gastroenterol Hepatol 2013 Aug;25(8):948-52. doi: 10.1097/MEG.0b013e32835fb9ee. PMID: 23510964

Diagnosis

MR imaging features of multiple biliary hamartomas (Von Meyenburg Complex): A pictorial review and differential diagnosis.
Boraschi P, Scalise P, Tarantini G, Colombatto P, Donati F
J Med Imaging Radiat Oncol 2021 Jun;65(3):323-330. Epub 2021 Mar 25 doi: 10.1111/1754-9485.13173. PMID: 33768689
Multiple Biliary Hamartomas, The ''Von Meyenburg Complexes''.
Jáquez-Quintana JO, Reyes-Cabello EA, Bosques-Padilla FJ
Ann Hepatol 2017 Sep-Oct;16(5):812-813. doi: 10.5604/01.3001.0010.2822. PMID: 28809728
A study of multiple biliary hamartomas based on 1697 liver biopsies.
Lin S, Weng Z, Xu J, Wang MF, Zhu YY, Jiang JJ
Eur J Gastroenterol Hepatol 2013 Aug;25(8):948-52. doi: 10.1097/MEG.0b013e32835fb9ee. PMID: 23510964
Cystic tumors of the liver: a practical approach.
Del Poggio P, Buonocore M
World J Gastroenterol 2008 Jun 21;14(23):3616-20. doi: 10.3748/wjg.14.3616. PMID: 18595127Free PMC Article
Multiple biliary hamartomas: magnetic resonance features with histopathologic correlation.
Tohmé-Noun C, Cazals D, Noun R, Menassa L, Valla D, Vilgrain V
Eur Radiol 2008 Mar;18(3):493-9. Epub 2007 Oct 13 doi: 10.1007/s00330-007-0790-z. PMID: 17934738

Prognosis

Multiple Biliary Hamartomas, The ''Von Meyenburg Complexes''.
Jáquez-Quintana JO, Reyes-Cabello EA, Bosques-Padilla FJ
Ann Hepatol 2017 Sep-Oct;16(5):812-813. doi: 10.5604/01.3001.0010.2822. PMID: 28809728
A study of multiple biliary hamartomas based on 1697 liver biopsies.
Lin S, Weng Z, Xu J, Wang MF, Zhu YY, Jiang JJ
Eur J Gastroenterol Hepatol 2013 Aug;25(8):948-52. doi: 10.1097/MEG.0b013e32835fb9ee. PMID: 23510964
Cystic tumors of the liver: a practical approach.
Del Poggio P, Buonocore M
World J Gastroenterol 2008 Jun 21;14(23):3616-20. doi: 10.3748/wjg.14.3616. PMID: 18595127Free PMC Article
Hilar bile duct cancer associated with preoperatively undetectable von Meyenburg complex--report of a case.
Eguchi S, Tajima Y, Yanaga K, Okudaira S, Furui J, Hayashi T, Kanematsu T
Hepatogastroenterology 2004 Sep-Oct;51(59):1301-3. PMID: 15362738

Clinical prediction guides

Multiple Biliary Hamartomas, The ''Von Meyenburg Complexes''.
Jáquez-Quintana JO, Reyes-Cabello EA, Bosques-Padilla FJ
Ann Hepatol 2017 Sep-Oct;16(5):812-813. doi: 10.5604/01.3001.0010.2822. PMID: 28809728
Cystic tumors of the liver: a practical approach.
Del Poggio P, Buonocore M
World J Gastroenterol 2008 Jun 21;14(23):3616-20. doi: 10.3748/wjg.14.3616. PMID: 18595127Free PMC Article

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