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Abnormal nasal septum morphology

MedGen UID:
1374137
•Concept ID:
C4316811
•
Anatomical Abnormality
Synonyms: Abnormality of septum of nose; Abnormality of the nasal septum; Anomaly of nasal septum; Anomaly of septum of nose
 
HPO: HP:0000419

Definition

An abnormality of the nasal septum. [from HPO]

Conditions with this feature

Carey-Fineman-Ziter syndrome 2
MedGen UID:
1800921
•Concept ID:
C5677012
•
Disease or Syndrome
Carey-Fineman-Ziter syndrome-2 (CFZS2) is an autosomal recessive disorder characterized by weakness of the facial musculature, hypomimic facies, increased overbite, micrognathia, and facial dysmorphism. Other features may include failure to thrive, axial hypotonia, and progressive scoliosis (Ramirez-Martinez et al., 2022). For a discussion of genetic heterogeneity of Carey-Fineman-Ziter syndrome, see CFZS1 (254940).
See: Condition Record
Carey-Fineman-Ziter syndrome 2

Professional guidelines

PubMed

Diagnosis and management of septal deviation and nasal valve collapse - a survey of Canadian otolaryngologists.
Wang Y, Bonaparte JP
J Otolaryngol Head Neck Surg 2019 Dec 16;48(1):71. doi: 10.1186/s40463-019-0394-z. PMID: 31842991Free PMC Article
Management of Pediatric Nasal Surgery (Rhinoplasty).
Johnson MD
Facial Plast Surg Clin North Am 2017 May;25(2):211-221. Epub 2017 Feb 21 doi: 10.1016/j.fsc.2016.12.006. PMID: 28340652
Nose underdevelopment - etiology, diagnosis and treatment.
Fijałkowska M, Antoszewski B
Otolaryngol Pol 2016 Apr 30;70(2):13-8. doi: 10.5604/00306657.1199344. PMID: 27386828

Recent clinical studies

Etiology

The Relationship Between Degree of Nasal Septum Deviation With Sinonasal Structures and Variations.
Atsal G, Demir E, Yildirim O, Edizer DT, Olgun L
J Craniofac Surg 2022 Jul-Aug 01;33(5):e447-e449. Epub 2021 Oct 21 doi: 10.1097/SCS.0000000000008274. PMID: 34690315
Nasal function and CPAP compliance.
Inoue A, Chiba S, Matsuura K, Osafune H, Capasso R, Wada K
Auris Nasus Larynx 2019 Aug;46(4):548-558. Epub 2018 Dec 8 doi: 10.1016/j.anl.2018.11.006. PMID: 30538069
Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Pediatric nasal surgery: timing and technique.
Gary CC
Curr Opin Otolaryngol Head Neck Surg 2017 Aug;25(4):286-290. doi: 10.1097/MOO.0000000000000378. PMID: 28509670
Refinements in extracorporal septoplasty.
Gubisch W, Constantinescu MA
Plast Reconstr Surg 1999 Sep;104(4):1131-9; discussion 1140-2. doi: 10.1097/00006534-199909040-00038. PMID: 10654757

Diagnosis

Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Caudal septum surgery techniques reviewed.
Cobo R, Caldas A
Curr Opin Otolaryngol Head Neck Surg 2017 Feb;25(1):4-11. doi: 10.1097/MOO.0000000000000321. PMID: 27846021
Nasal obstruction in children.
Leboulanger N
Eur Ann Otorhinolaryngol Head Neck Dis 2016 Jun;133(3):183-6. Epub 2015 Oct 23 doi: 10.1016/j.anorl.2015.09.011. PMID: 26471039
Septoplasty pearls.
Dobratz EJ, Park SS
Otolaryngol Clin North Am 2009 Jun;42(3):527-37. doi: 10.1016/j.otc.2009.03.003. PMID: 19486747
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Therapy

Olfactory cleft dilatation.
Jankowski R, Nguyen DT, Gallet P, Rumeau C
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec;135(6):437-441. Epub 2018 Jun 20 doi: 10.1016/j.anorl.2018.05.008. PMID: 29934261
Rhinoseptoplasty in children.
Maniglia CP, Maniglia JV
Braz J Otorhinolaryngol 2017 Jul-Aug;83(4):416-419. Epub 2016 May 31 doi: 10.1016/j.bjorl.2016.04.019. PMID: 27339699Free PMC Article
Extracorporeal Septoplasty: External and Endonasal Techniques.
Wu PS, Hamilton GS 3rd
Facial Plast Surg 2016 Feb;32(1):22-8. Epub 2016 Feb 10 doi: 10.1055/s-0035-1570123. PMID: 26862960
The importance of the nasal septum in the deviated nose.
Sykes JM, Kim JE, Shaye D, Boccieri A
Facial Plast Surg 2011 Oct;27(5):413-21. Epub 2011 Oct 25 doi: 10.1055/s-0031-1288928. PMID: 22028006
Nasal septum and facial development.
Lancet 1991 Oct 19;338(8773):983-4. PMID: 1681348

Prognosis

Nasal function and CPAP compliance.
Inoue A, Chiba S, Matsuura K, Osafune H, Capasso R, Wada K
Auris Nasus Larynx 2019 Aug;46(4):548-558. Epub 2018 Dec 8 doi: 10.1016/j.anl.2018.11.006. PMID: 30538069
Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Cat eye syndrome.
Sharma D, Murki S, Pratap T, Vasikarla M
BMJ Case Rep 2014 May 19;2014 doi: 10.1136/bcr-2014-203923. PMID: 24842361Free PMC Article
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Supernumerary nostrils.
Chen MT, Yeong EK
Br J Plast Surg 1992 Oct;45(7):557-8. doi: 10.1016/0007-1226(92)90156-r. PMID: 1446204

Clinical prediction guides

Postoperative Clinical and Radiological Analysis of Deviated Noses.
Altinel D, Serin M, Toplu G
Ann Plast Surg 2022 Nov 1;89(5):487-491. Epub 2022 Sep 9 doi: 10.1097/SAP.0000000000003297. PMID: 36279572
Nasal function and CPAP compliance.
Inoue A, Chiba S, Matsuura K, Osafune H, Capasso R, Wada K
Auris Nasus Larynx 2019 Aug;46(4):548-558. Epub 2018 Dec 8 doi: 10.1016/j.anl.2018.11.006. PMID: 30538069
Review and update on extracorporeal septoplasty.
McGrath M, Bell E, Locketz GD, Becker DG
Curr Opin Otolaryngol Head Neck Surg 2019 Feb;27(1):1-6. doi: 10.1097/MOO.0000000000000509. PMID: 30507685
Pediatric septorhinoplasty.
Funamura JL, Sykes JM
Facial Plast Surg Clin North Am 2014 Nov;22(4):503-8. Epub 2014 Nov 8 doi: 10.1016/j.fsc.2014.07.005. PMID: 25444724
Supernumerary nostrils.
Chen MT, Yeong EK
Br J Plast Surg 1992 Oct;45(7):557-8. doi: 10.1016/0007-1226(92)90156-r. PMID: 1446204

Recent systematic reviews

Anatomical variations and abnormalities of the maxillary region and clinical implications: A systematic review and metaanalysis.
Valenzuela-Fuenzalida JJ, Baez-Flores B, Sepúlveda RÁ, Medina CM, Pérez R, López E, Sanchis J, Orellana Donoso M, Silva JL, Rodriguez MC, Iwanaga J
Medicine (Baltimore) 2023 Sep 22;102(38):e34510. doi: 10.1097/MD.0000000000034510. PMID: 37747000Free PMC Article
Long-term patient-related outcome measures of septoplasty: a systematic review.
Tsang CLN, Nguyen T, Sivesind T, Cervin A
Eur Arch Otorhinolaryngol 2018 May;275(5):1039-1048. Epub 2018 Jan 13 doi: 10.1007/s00405-018-4874-y. PMID: 29332171
Effect of non-surgical maxillary expansion on the nasal septum deviation: a systematic review.
Aziz T, Ansari K, Lagravere MO, Major MP, Flores-Mir C
Prog Orthod 2015;16:15. Epub 2015 Jun 4 doi: 10.1186/s40510-015-0084-y. PMID: 26061988Free PMC Article
Measurement tools for the diagnosis of nasal septal deviation: a systematic review.
Aziz T, Biron VL, Ansari K, Flores-Mir C
J Otolaryngol Head Neck Surg 2014 Apr 24;43(1):11. doi: 10.1186/1916-0216-43-11. PMID: 24762010Free PMC Article
Do chronic changes in nasal airflow have any physiological or pathological effect on the nose and paranasal sinuses? A systematic review.
Boyce J, Eccles R
Clin Otolaryngol 2006 Feb;31(1):15-9. doi: 10.1111/j.1749-4486.2006.01125.x. PMID: 16441795

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