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Abnormal liver sonography

MedGen UID:: 1374725
•Concept ID:: C4476999
•: Finding

HPO:	HP:0031140

Definition

An abnormal appearance of the liver or any of its components on sonography (ultrasound). [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal liver sonography

Disorder of digestive system
- Abnormality of the digestive system
  - Abnormality of the abdominal organs
    - Abnormality of the liver
      - Abnormal liver morphology
        Abnormal liver sonography
        Abnormal hepatic echogenicity
        Decreased hepatic echogenicity
        Increased hepatic echogenicity
        Coarsened hepatic echotexture
        Starry sky appearance on hepatic sonography

Professional guidelines

PubMed

Hepatorenal syndrome: pathophysiology, diagnosis, and management.

Simonetto DA, Gines P, Kamath PS
BMJ 2020 Sep 14;370:m2687. doi: 10.1136/bmj.m2687. PMID: 32928750

Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.

Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324

Cirrhosis: Diagnosis and Management.

Smith A, Baumgartner K, Bositis C
Am Fam Physician 2019 Dec 15;100(12):759-770. PMID: 31845776

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Recent clinical studies

Etiology

Imaging of Fontan-Associated Liver Disease.

Brown MJ, Kolbe AB, Hull NC, Hilscher M, Kamath PS, Yalon M, Gu CN, Amawi ADT, Venkatesh SK, Wells ML
J Comput Assist Tomogr 2024 Jan-Feb 01;48(1):1-11. Epub 2023 Aug 10 doi: 10.1097/RCT.0000000000001533. PMID: 37574655

Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.

Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324

Neonatal Jaundice.

Abbey P, Kandasamy D, Naranje P
Indian J Pediatr 2019 Sep;86(9):830-841. Epub 2019 Feb 21 doi: 10.1007/s12098-019-02856-0. PMID: 30790186

Neonatal cancer.

Orbach D, Sarnacki S, Brisse HJ, Gauthier-Villars M, Jarreau PH, Tsatsaris V, Baruchel A, Zerah M, Seigneur E, Peuchmaur M, Doz F
Lancet Oncol 2013 Dec;14(13):e609-20. doi: 10.1016/S1470-2045(13)70236-5. PMID: 24275134

Meckel syndrome.

Salonen R, Paavola P
J Med Genet 1998 Jun;35(6):497-501. doi: 10.1136/jmg.35.6.497. PMID: 9643292 Free PMC Article

See all (1715)

Diagnosis

Microvascular Flow Imaging: A State-of-the-Art Review of Clinical Use and Promise.

Aziz MU, Eisenbrey JR, Deganello A, Zahid M, Sharbidre K, Sidhu P, Robbin ML
Radiology 2022 Nov;305(2):250-264. Epub 2022 Sep 27 doi: 10.1148/radiol.213303. PMID: 36165794 Free PMC Article

Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.

Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324

Endoscopic Ultrasound-guided Liver Biopsy.

Diehl DL
Gastrointest Endosc Clin N Am 2019 Apr;29(2):173-186. Epub 2019 Feb 2 doi: 10.1016/j.giec.2018.11.002. PMID: 30846147

Neonatal Jaundice.

Abbey P, Kandasamy D, Naranje P
Indian J Pediatr 2019 Sep;86(9):830-841. Epub 2019 Feb 21 doi: 10.1007/s12098-019-02856-0. PMID: 30790186

Biliary atresia: A comprehensive review.

Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637

See all (2551)

Therapy

Pediatric Hepatocellular Carcinoma.

Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229

A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study.

Harrison SA, Ratziu V, Boursier J, Francque S, Bedossa P, Majd Z, Cordonnier G, Sudrik FB, Darteil R, Liebe R, Magnanensi J, Hajji Y, Brozek J, Roudot A, Staels B, Hum DW, Megnien SJ, Hosmane S, Dam N, Chaumat P, Hanf R, Anstee QM, Sanyal AJ
Lancet Gastroenterol Hepatol 2020 Nov;5(11):970-985. Epub 2020 Aug 5 doi: 10.1016/S2468-1253(20)30252-1. PMID: 32763196

Autosomal dominant polycystic kidney disease.

Cornec-Le Gall E, Alam A, Perrone RD
Lancet 2019 Mar 2;393(10174):919-935. Epub 2019 Feb 25 doi: 10.1016/S0140-6736(18)32782-X. PMID: 30819518

Biliary atresia: A comprehensive review.

Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637

Normal splenic size in infants and children: sonographic measurements.

Rosenberg HK, Markowitz RI, Kolberg H, Park C, Hubbard A, Bellah RD
AJR Am J Roentgenol 1991 Jul;157(1):119-21. doi: 10.2214/ajr.157.1.2048509. PMID: 2048509

See all (694)

Prognosis

Imaging of Fontan-Associated Liver Disease.

Pediatric Hepatocellular Carcinoma.

Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229

Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.

Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324

Biliary atresia: A comprehensive review.

Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637

Biliary atresia.

Baumann U, Ure B
Clin Res Hepatol Gastroenterol 2012 Jun;36(3):257-9. Epub 2012 May 18 doi: 10.1016/j.clinre.2012.03.017. PMID: 22609296

See all (1200)

Clinical prediction guides

A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study.

Prediction tools in congenital diaphragmatic hernia.

Jancelewicz T, Brindle ME
Semin Perinatol 2020 Feb;44(1):151165. Epub 2019 Jul 31 doi: 10.1053/j.semperi.2019.07.004. PMID: 31676044

Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.

Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324

Ultrasonography for Noninvasive Assessment of Portal Hypertension.

Maruyama H, Yokosuka O
Gut Liver 2017 Jul 15;11(4):464-473. doi: 10.5009/gnl16078. PMID: 28267700 Free PMC Article

Imaging in pediatric liver transplantation.

Monti L, Soglia G, Tomà P
Radiol Med 2016 May;121(5):378-90. Epub 2016 Feb 24 doi: 10.1007/s11547-016-0628-3. PMID: 26909515

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Recent systematic reviews

Applications of elastography in operative neurosurgery: A systematic review.

Hersh AM, Weber-Levine C, Jiang K, Young L, Kerensky M, Routkevitch D, Tsehay Y, Perdomo-Pantoja A, Judy BF, Lubelski D, Theodore N, Manbachi A
J Clin Neurosci 2022 Oct;104:18-28. Epub 2022 Aug 4 doi: 10.1016/j.jocn.2022.07.019. PMID: 35933785 Free PMC Article

Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA
Am J Obstet Gynecol 2022 Feb;226(2S):S1222-S1236. Epub 2020 Aug 20 doi: 10.1016/j.ajog.2020.08.018. PMID: 32828743

Outcome of prenatally diagnosed fetal heterotaxy: systematic review and meta-analysis.

Buca DIP, Khalil A, Rizzo G, Familiari A, Di Giovanni S, Liberati M, Murgano D, Ricciardulli A, Fanfani F, Scambia G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Mar;51(3):323-330. doi: 10.1002/uog.17546. PMID: 28603940

Outcomes associated with fetal hepatobiliary cysts: systematic review and meta-analysis.

Leombroni M, Buca D, Celentano C, Liberati M, Bascietto F, Gustapane S, Marrone L, Manzoli L, Rizzo G, D'Antonio F
Ultrasound Obstet Gynecol 2017 Aug;50(2):167-174. Epub 2017 Jul 9 doi: 10.1002/uog.17244. PMID: 27553859

Association of Nonalcoholic Fatty Liver Disease with Subclinical Cardiovascular Changes: A Systematic Review and Meta-Analysis.

Bonci E, Chiesa C, Versacci P, Anania C, Silvestri L, Pacifico L
Biomed Res Int 2015;2015:213737. Epub 2015 Jul 26 doi: 10.1155/2015/213737. PMID: 26273598 Free PMC Article

See all (22)

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Abnormal liver sonography

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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