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Hidebound

MedGen UID:
1375699
•Concept ID:
C4330260
•
Finding

Definition

Skin that is abnormally dry and stiff, lacking pliancy and closely adhered to the underlying flesh. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHidebound

Professional guidelines

PubMed

Investigator feedback about the 2005 NIH diagnostic and scoring criteria for chronic GVHD.
Inamoto Y, Jagasia M, Wood WA, Pidala J, Palmer J, Khera N, Weisdorf D, Carpenter PA, Flowers ME, Jacobsohn D, Martin PJ, Lee SJ, Pavletic SZ; Chronic GVHD Consortium
Bone Marrow Transplant 2014 Apr;49(4):532-8. Epub 2014 Jan 27 doi: 10.1038/bmt.2013.225. PMID: 24464142Free PMC Article

Recent clinical studies

Etiology

A Flexible Suspension Technique of Blepharoplasty: Clinical Application and Comparison with Traditional Technique.
Pan L, Sun Y, Yan S, Shi H, Jin T, Li J, Zhang L, Wu S
Aesthetic Plast Surg 2019 Apr;43(2):404-411. Epub 2019 Feb 12 doi: 10.1007/s00266-019-01317-5. PMID: 30756143
Fear of change itself. A few positive developments only underscore healthcare's hidebound nature.
Sloane T
Mod Healthc 2007 Aug 20;37(33):22. PMID: 17853742
A single-center pilot validation study of a new chronic GVHD skin scoring system.
Greinix HT, Pohlreich D, Maalouf J, Soukup P, Supper V, Kalhs P, Knobler RM
Biol Blood Marrow Transplant 2007 Jun;13(6):715-23. Epub 2007 Apr 23 doi: 10.1016/j.bbmt.2007.02.007. PMID: 17531782
Developing your leadership pipeline.
Conger JA, Fulmer RM
Harv Bus Rev 2003 Dec;81(12):76-84, 125. PMID: 14712546
Treatment of systemic sclerosis with recombinant interferon-gamma. A phase I/II clinical trial.
Freundlich B, Jimenez SA, Steen VD, Medsger TA Jr, Szkolnicki M, Jaffe HS
Arthritis Rheum 1992 Oct;35(10):1134-42. doi: 10.1002/art.1780351005. PMID: 1418004

Diagnosis

Anaphylaxis across Europe: are pollen food syndrome and lipid transfer protein allergy so far apart?
Olivieri B, Stoenchev KV, Skypala IJ
Curr Opin Allergy Clin Immunol 2022 Oct 1;22(5):291-297. Epub 2022 Aug 4 doi: 10.1097/ACI.0000000000000847. PMID: 35942860
Hidebound sign: Small bowel in systemic sclerosis.
Xiang H, Han J, Ridley WE, Ridley LJ
J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:80. doi: 10.1111/1754-9485.28_12784. PMID: 30309195
Gastrointestinal: Hide-bound bowel.
Hoversten P, Bledsoe A, Sweetser S
J Gastroenterol Hepatol 2018 Aug;33(8):1433. Epub 2018 Jun 5 doi: 10.1111/jgh.14283. PMID: 29873115
Investigator feedback about the 2005 NIH diagnostic and scoring criteria for chronic GVHD.
Inamoto Y, Jagasia M, Wood WA, Pidala J, Palmer J, Khera N, Weisdorf D, Carpenter PA, Flowers ME, Jacobsohn D, Martin PJ, Lee SJ, Pavletic SZ; Chronic GVHD Consortium
Bone Marrow Transplant 2014 Apr;49(4):532-8. Epub 2014 Jan 27 doi: 10.1038/bmt.2013.225. PMID: 24464142Free PMC Article
The eosinophilia-myalgia syndrome and related disorders.
Kaufman LD
Recenti Prog Med 1991 May;82(5):286-90. PMID: 1887155

Therapy

Hidebound sign: Small bowel in systemic sclerosis.
Xiang H, Han J, Ridley WE, Ridley LJ
J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:80. doi: 10.1111/1754-9485.28_12784. PMID: 30309195
Investigator feedback about the 2005 NIH diagnostic and scoring criteria for chronic GVHD.
Inamoto Y, Jagasia M, Wood WA, Pidala J, Palmer J, Khera N, Weisdorf D, Carpenter PA, Flowers ME, Jacobsohn D, Martin PJ, Lee SJ, Pavletic SZ; Chronic GVHD Consortium
Bone Marrow Transplant 2014 Apr;49(4):532-8. Epub 2014 Jan 27 doi: 10.1038/bmt.2013.225. PMID: 24464142Free PMC Article
A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: effects on cutaneous fibrosis and interleukin 2 receptor levels.
Polisson RP, Gilkeson GS, Pyun EH, Pisetsky DS, Smith EA, Simon LS
J Rheumatol 1996 Apr;23(4):654-8. PMID: 8730122
Treatment of systemic sclerosis with recombinant interferon-gamma. A phase I/II clinical trial.
Freundlich B, Jimenez SA, Steen VD, Medsger TA Jr, Szkolnicki M, Jaffe HS
Arthritis Rheum 1992 Oct;35(10):1134-42. doi: 10.1002/art.1780351005. PMID: 1418004
Plasmapheresis and immunosuppressive drug therapy in scleroderma.
Dau PC, Kahaleh MB, Sagebiel RW
Arthritis Rheum 1981 Sep;24(9):1128-36. doi: 10.1002/art.1780240903. PMID: 6975636

Prognosis

Gastrointestinal: Hide-bound bowel.
Hoversten P, Bledsoe A, Sweetser S
J Gastroenterol Hepatol 2018 Aug;33(8):1433. Epub 2018 Jun 5 doi: 10.1111/jgh.14283. PMID: 29873115
A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: effects on cutaneous fibrosis and interleukin 2 receptor levels.
Polisson RP, Gilkeson GS, Pyun EH, Pisetsky DS, Smith EA, Simon LS
J Rheumatol 1996 Apr;23(4):654-8. PMID: 8730122
Treatment of systemic sclerosis with recombinant interferon-gamma. A phase I/II clinical trial.
Freundlich B, Jimenez SA, Steen VD, Medsger TA Jr, Szkolnicki M, Jaffe HS
Arthritis Rheum 1992 Oct;35(10):1134-42. doi: 10.1002/art.1780351005. PMID: 1418004
Extrapulmonary thoracic restriction (hidebound chest) complicating eosinophilic fasciitis.
Chalker RB, Dickey BF, Rosenthal NC, Simms RW
Chest 1991 Nov;100(5):1453-5. doi: 10.1378/chest.100.5.1453. PMID: 1935312

Clinical prediction guides

A Flexible Suspension Technique of Blepharoplasty: Clinical Application and Comparison with Traditional Technique.
Pan L, Sun Y, Yan S, Shi H, Jin T, Li J, Zhang L, Wu S
Aesthetic Plast Surg 2019 Apr;43(2):404-411. Epub 2019 Feb 12 doi: 10.1007/s00266-019-01317-5. PMID: 30756143
Gastrointestinal: Hide-bound bowel.
Hoversten P, Bledsoe A, Sweetser S
J Gastroenterol Hepatol 2018 Aug;33(8):1433. Epub 2018 Jun 5 doi: 10.1111/jgh.14283. PMID: 29873115
Investigator feedback about the 2005 NIH diagnostic and scoring criteria for chronic GVHD.
Inamoto Y, Jagasia M, Wood WA, Pidala J, Palmer J, Khera N, Weisdorf D, Carpenter PA, Flowers ME, Jacobsohn D, Martin PJ, Lee SJ, Pavletic SZ; Chronic GVHD Consortium
Bone Marrow Transplant 2014 Apr;49(4):532-8. Epub 2014 Jan 27 doi: 10.1038/bmt.2013.225. PMID: 24464142Free PMC Article
A single-center pilot validation study of a new chronic GVHD skin scoring system.
Greinix HT, Pohlreich D, Maalouf J, Soukup P, Supper V, Kalhs P, Knobler RM
Biol Blood Marrow Transplant 2007 Jun;13(6):715-23. Epub 2007 Apr 23 doi: 10.1016/j.bbmt.2007.02.007. PMID: 17531782
Extrapulmonary thoracic restriction (hidebound chest) complicating eosinophilic fasciitis.
Chalker RB, Dickey BF, Rosenthal NC, Simms RW
Chest 1991 Nov;100(5):1453-5. doi: 10.1378/chest.100.5.1453. PMID: 1935312

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