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Recurrent Childhood Cerebellar Astrocytoma

MedGen UID:
137885
•Concept ID:
C0338338
•
Neoplastic Process
Synonyms: Recurrent Childhood Astrocytoma of Cerebellum; Recurrent Childhood Astrocytoma of the Cerebellum; Recurrent Pediatric Astrocytoma of Cerebellum; Recurrent Pediatric Astrocytoma of the Cerebellum; Recurrent Pediatric Cerebellar Astrocytoma; Relapsed Childhood Astrocytoma of Cerebellum; Relapsed Childhood Astrocytoma of the Cerebellum; Relapsed Childhood Cerebellar Astrocytoma; Relapsed Pediatric Astrocytoma of Cerebellum; Relapsed Pediatric Astrocytoma of the Cerebellum; Relapsed Pediatric Cerebellar Astrocytoma

Definition

Regrowth of benign and malignant childhood cerebellar astrocytomas that have previously been subjected to surgical resection and less frequently other forms of therapy such as radiation or chemotherapy. Recurrence of benign tumors (e.g., (pilocytic astrocytoma) may respond to a second surgical procedure. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Cerebellar Astrocytoma

Professional guidelines

PubMed

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700

Recent clinical studies

Etiology

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
The benefit of surveillance imaging for paediatric cerebellar pilocytic astrocytoma.
McAuley E, Brophy H, Hayden J, Pettorini B, Parks C, Avula S, Mallucci C, Pizer B
Childs Nerv Syst 2019 May;35(5):801-805. Epub 2019 Feb 15 doi: 10.1007/s00381-019-04078-3. PMID: 30770993
Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
Saunders DE, Phipps KP, Wade AM, Hayward RD
J Neurosurg 2005 Mar;102(2 Suppl):172-8. doi: 10.3171/jns.2005.102.2.0172. PMID: 16156227
Benign cerebellar astrocytomas in children.
Pencalet P, Maixner W, Sainte-Rose C, Lellouch-Tubiana A, Cinalli G, Zerah M, Pierre-Kahn A, Hoppe-Hirsch E, Bourgeois M, Renier D
J Neurosurg 1999 Feb;90(2):265-73. doi: 10.3171/jns.1999.90.2.0265. PMID: 9950497
Cerebellar astrocytoma of childhood: long-term follow-up.
Sgouros S, Fineron PW, Hockley AD
Childs Nerv Syst 1995 Feb;11(2):89-96. doi: 10.1007/BF00303812. PMID: 7758018

Diagnosis

Pediatric-Like Brain Tumors in Adults.
Dias SF, Richards O, Elliot M, Chumas P
Adv Tech Stand Neurosurg 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5. PMID: 38592530
Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
The benefit of surveillance imaging for paediatric cerebellar pilocytic astrocytoma.
McAuley E, Brophy H, Hayden J, Pettorini B, Parks C, Avula S, Mallucci C, Pizer B
Childs Nerv Syst 2019 May;35(5):801-805. Epub 2019 Feb 15 doi: 10.1007/s00381-019-04078-3. PMID: 30770993
Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
Saunders DE, Phipps KP, Wade AM, Hayward RD
J Neurosurg 2005 Mar;102(2 Suppl):172-8. doi: 10.3171/jns.2005.102.2.0172. PMID: 16156227
Malignant supratentorial gliomas in childhood.
Prados M, Levin V
Pediatr Neurosci 1987;13(3):144-51. doi: 10.1159/000120320. PMID: 3331428

Therapy

Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma.
Hope AJ, Mansur DB, Tu PH, Simpson JR
Childs Nerv Syst 2006 Sep;22(9):1201-7. Epub 2006 Mar 29 doi: 10.1007/s00381-006-0062-2. PMID: 16570196
Second surgery for recurrent pilocytic astrocytoma in children.
Bowers DC, Krause TP, Aronson LJ, Barzi A, Burger PC, Carson BS, Weingart JD, Wharam MD, Melhem ER, Cohen KJ
Pediatr Neurosurg 2001 May;34(5):229-34. doi: 10.1159/000056027. PMID: 11423771
Malignant supratentorial gliomas in childhood.
Prados M, Levin V
Pediatr Neurosci 1987;13(3):144-51. doi: 10.1159/000120320. PMID: 3331428
Rhabdomyosarcoma of the ear in childhood. A report from the Intergroup Rhabdomyosarcoma Study-I.
Raney RB Jr, Lawrence W Jr, Maurer HM, Lindberg RD, Newton WA Jr, Ragab AH, Tefft M, Foulkes MA
Cancer 1983 Jun 15;51(12):2356-61. doi: 10.1002/1097-0142(19830615)51:12<2356::aid-cncr2820511232>3.0.co;2-l. PMID: 6342748
Partially resected and irradiated cerebellar astrocytoma of childhood: malignant evolution after 28 years.
Budka H
Acta Neurochir (Wien) 1975;32(1-2):139-46. doi: 10.1007/BF01405911. PMID: 1163315

Prognosis

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
The benefit of surveillance imaging for paediatric cerebellar pilocytic astrocytoma.
McAuley E, Brophy H, Hayden J, Pettorini B, Parks C, Avula S, Mallucci C, Pizer B
Childs Nerv Syst 2019 May;35(5):801-805. Epub 2019 Feb 15 doi: 10.1007/s00381-019-04078-3. PMID: 30770993
Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
Saunders DE, Phipps KP, Wade AM, Hayward RD
J Neurosurg 2005 Mar;102(2 Suppl):172-8. doi: 10.3171/jns.2005.102.2.0172. PMID: 16156227
Cerebellar astrocytoma of childhood: long-term follow-up.
Sgouros S, Fineron PW, Hockley AD
Childs Nerv Syst 1995 Feb;11(2):89-96. doi: 10.1007/BF00303812. PMID: 7758018
Cerebellar astrocytomas. Part II. Pathologic features indicative of malignancy.
Ilgren EB, Stiller CA
Clin Neuropathol 1987 Sep-Oct;6(5):201-14. PMID: 3319332

Clinical prediction guides

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
CORNEAL NEUROTIZATION IN A PATIENT WITH SEVERE NEUROTROPHIC KERATOPATHY. CASE REPORT.
Rusňák Š, Hecová L, Štěpánek D, Sobotová M
Cesk Slov Oftalmol 2021 Winter;77(3):146–152. doi: 10.31348/2021/17. PMID: 35130706
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott PA, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM; International Cancer Genome Consortium PedBrain Tumor Project
Nat Genet 2013 Aug;45(8):927-32. Epub 2013 Jun 30 doi: 10.1038/ng.2682. PMID: 23817572Free PMC Article
Predicting disease progression in childhood cerebellar astrocytoma.
Smoots DW, Geyer JR, Lieberman DM, Berger MS
Childs Nerv Syst 1998 Nov;14(11):636-48. doi: 10.1007/s003810050290. PMID: 9840364
Chromosomal characteristics of childhood brain tumors.
Bigner SH, McLendon RE, Fuchs H, McKeever PE, Friedman HS
Cancer Genet Cytogenet 1997 Sep;97(2):125-34. doi: 10.1016/s0165-4608(96)00404-9. PMID: 9283596

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