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Anterior displacement of the papillary muscles

MedGen UID:
1382914
•Concept ID:
C4476784
•
Anatomical Abnormality
Synonym: Anteriorly displaced papillary muscles
 
HPO: HP:0025448

Definition

Abnormally anterior location of the papillary muscles of the left ventricle. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior displacement of the papillary muscles

Recent clinical studies

Etiology

The Role of Mitral Valve in Hypertrophic Obstructive Cardiomyopathy: An Updated Review.
Sakellaropoulos S, Svab S, Mohammed M, Dimitra L, Mitsis A
Curr Probl Cardiol 2021 Mar;46(3):100641. Epub 2020 Jun 4 doi: 10.1016/j.cpcardiol.2020.100641. PMID: 32586596
Structural abnormalities in hypertrophic cardiomyopathy beyond left ventricular hypertrophy by multimodality imaging evaluation.
Urbano-Moral JA, Gutierrez-Garcia-Moreno L, Rodriguez-Palomares JF, Matabuena-Gomez-Limon J, Niella N, Maldonado G, Valle-Racero JI, Niella M, Teixido-Tura G, Garcia-Dorado D, Ferrazzi P, Pandian NG, Evangelista-Masip A
Echocardiography 2019 Jul;36(7):1241-1252. Epub 2019 Jun 4 doi: 10.1111/echo.14393. PMID: 31162742
Echocardiography before and after resect-plicate-release surgical myectomy for obstructive hypertrophic cardiomyopathy.
Halpern DG, Swistel DG, Po JR, Joshi R, Winson G, Arabadjian M, Lopresto C, Kushner J, Kim B, Balaram SK, Sherrid MV
J Am Soc Echocardiogr 2015 Nov;28(11):1318-28. Epub 2015 Aug 10 doi: 10.1016/j.echo.2015.07.002. PMID: 26272699
Influence of chronic tethering of the mitral valve on mitral leaflet size and coaptation in functional mitral regurgitation.
Saito K, Okura H, Watanabe N, Obase K, Tamada T, Koyama T, Hayashida A, Neishi Y, Kawamoto T, Yoshida K
JACC Cardiovasc Imaging 2012 Apr;5(4):337-45. doi: 10.1016/j.jcmg.2011.10.004. PMID: 22498321
Posterior shift of the anterior papillary muscle in patients with heart failure: a potential role in the effect of cardiac resynchronization therapy.
Hara T, Yamashiro K, Okajima K, Hayashi T, Kajiya T
Int Heart J 2009 Nov;50(6):773-82. doi: 10.1536/ihj.50.773. PMID: 19952474

Diagnosis

The Role of Mitral Valve in Hypertrophic Obstructive Cardiomyopathy: An Updated Review.
Sakellaropoulos S, Svab S, Mohammed M, Dimitra L, Mitsis A
Curr Probl Cardiol 2021 Mar;46(3):100641. Epub 2020 Jun 4 doi: 10.1016/j.cpcardiol.2020.100641. PMID: 32586596
Echocardiography before and after resect-plicate-release surgical myectomy for obstructive hypertrophic cardiomyopathy.
Halpern DG, Swistel DG, Po JR, Joshi R, Winson G, Arabadjian M, Lopresto C, Kushner J, Kim B, Balaram SK, Sherrid MV
J Am Soc Echocardiogr 2015 Nov;28(11):1318-28. Epub 2015 Aug 10 doi: 10.1016/j.echo.2015.07.002. PMID: 26272699
Mitral valve and papillary muscle abnormalities in hypertrophic obstructive cardiomyopathy.
Teo EP, Teoh JG, Hung J
Curr Opin Cardiol 2015 Sep;30(5):475-82. doi: 10.1097/HCO.0000000000000200. PMID: 26192489
Assessment of mitral valve anatomy and geometry with multislice computed tomography.
Delgado V, Tops LF, Schuijf JD, de Roos A, Brugada J, Schalij MJ, Thomas JD, Bax JJ
JACC Cardiovasc Imaging 2009 May;2(5):556-65. doi: 10.1016/j.jcmg.2008.12.025. PMID: 19442940
Finite element analysis of the mitral apparatus: annulus shape effect and chordal force distribution.
Prot V, Haaverstad R, Skallerud B
Biomech Model Mechanobiol 2009 Feb;8(1):43-55. Epub 2008 Jan 10 doi: 10.1007/s10237-007-0116-8. PMID: 18193309

Therapy

Surgical treatment of functional ischemic mitral regurgitation.
Jensen H
Dan Med J 2015 Mar;62(3) PMID: 25748873
Reduction of mitral valve leaflet tethering by procedures targeting the subvalvular apparatus in addition to mitral annuloplasty.
Yamaguchi A, Adachi K, Yuri K, Kimura N, Kimura C, Tamura A, Adachi H
Circ J 2013;77(6):1461-5. Epub 2013 Feb 20 doi: 10.1253/circj.cj-12-1148. PMID: 23428660
Different influences of left ventricular remodeling on anterior and posterior mitral leaflet tethering.
Nakai H, Kaku K, Takeuchi M, Otani K, Yoshitani H, Haruki N, Tamura M, Okazaki M, Abe H, Tsutsumi A, Levine RA, Otsuji Y
Circ J 2012;76(10):2481-7. Epub 2012 Jun 21 doi: 10.1253/circj.cj-11-1527. PMID: 22785152
Mitral regurgitation after anteroapical myocardial infarction: new mechanistic insights.
Yosefy C, Beeri R, Guerrero JL, Vaturi M, Scherrer-Crosbie M, Handschumacher MD, Levine RA
Circulation 2011 Apr 12;123(14):1529-36. Epub 2011 Mar 28 doi: 10.1161/CIRCULATIONAHA.110.977843. PMID: 21444880Free PMC Article

Prognosis

Role of noninvasive imaging modalities to better understand the mechanism of left ventricular outflow tract obstruction and tailored lesion-specific treatment options.
Song JK
Circ J 2014;78(8):1808-15. Epub 2014 Jul 8 doi: 10.1253/circj.cj-14-0524. PMID: 25008367
Influence of chronic tethering of the mitral valve on mitral leaflet size and coaptation in functional mitral regurgitation.
Saito K, Okura H, Watanabe N, Obase K, Tamada T, Koyama T, Hayashida A, Neishi Y, Kawamoto T, Yoshida K
JACC Cardiovasc Imaging 2012 Apr;5(4):337-45. doi: 10.1016/j.jcmg.2011.10.004. PMID: 22498321
Posterior shift of the anterior papillary muscle in patients with heart failure: a potential role in the effect of cardiac resynchronization therapy.
Hara T, Yamashiro K, Okajima K, Hayashi T, Kajiya T
Int Heart J 2009 Nov;50(6):773-82. doi: 10.1536/ihj.50.773. PMID: 19952474
Assessment of mitral valve anatomy and geometry with multislice computed tomography.
Delgado V, Tops LF, Schuijf JD, de Roos A, Brugada J, Schalij MJ, Thomas JD, Bax JJ
JACC Cardiovasc Imaging 2009 May;2(5):556-65. doi: 10.1016/j.jcmg.2008.12.025. PMID: 19442940
Chordal geometry determines the shape and extent of systolic anterior mitral motion: in vitro studies.
Cape EG, Simons D, Jimoh A, Weyman AE, Yoganathan AP, Levine RA
J Am Coll Cardiol 1989 May;13(6):1438-48. doi: 10.1016/0735-1097(89)90326-4. PMID: 2703621

Clinical prediction guides

Intrinsic mitral valve alterations in hypertrophic cardiomyopathy sarcomere mutation carriers.
Groarke JD, Galazka PZ, Cirino AL, Lakdawala NK, Thune JJ, Bundgaard H, Orav EJ, Levine RA, Ho CY
Eur Heart J Cardiovasc Imaging 2018 Oct 1;19(10):1109-1116. doi: 10.1093/ehjci/jey095. PMID: 30052928Free PMC Article
Echocardiography before and after resect-plicate-release surgical myectomy for obstructive hypertrophic cardiomyopathy.
Halpern DG, Swistel DG, Po JR, Joshi R, Winson G, Arabadjian M, Lopresto C, Kushner J, Kim B, Balaram SK, Sherrid MV
J Am Soc Echocardiogr 2015 Nov;28(11):1318-28. Epub 2015 Aug 10 doi: 10.1016/j.echo.2015.07.002. PMID: 26272699
Posterior shift of the anterior papillary muscle in patients with heart failure: a potential role in the effect of cardiac resynchronization therapy.
Hara T, Yamashiro K, Okajima K, Hayashi T, Kajiya T
Int Heart J 2009 Nov;50(6):773-82. doi: 10.1536/ihj.50.773. PMID: 19952474
Importance of leaflet elongation in causing systolic anterior motion of the mitral valve.
He S, Hopmeyer J, Lefebvre XP, Schwammenthal E, Yoganathan AP, Levine RA
J Heart Valve Dis 1997 Mar;6(2):149-59. PMID: 9130123
Chordal geometry determines the shape and extent of systolic anterior mitral motion: in vitro studies.
Cape EG, Simons D, Jimoh A, Weyman AE, Yoganathan AP, Levine RA
J Am Coll Cardiol 1989 May;13(6):1438-48. doi: 10.1016/0735-1097(89)90326-4. PMID: 2703621

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