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Skeletal muscle steatosis

MedGen UID:
1383774
•Concept ID:
C4477033
•
Disease or Syndrome
Synonyms: Steatosis of skeletal muscle; Steatosis of skeletal muscles
 
HPO: HP:0040291

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkeletal muscle steatosis

Professional guidelines

PubMed

Expert consensus on diagnosis and treatment of very long-chain acyl-CoA dehydrogenase deficiency.
Division of Biochemistry and Metabolism, Medical Genetics Branch, Chinese Medical Association, Division of Genetics and Metabolism, Child Diseases and Health Care Branch, Chinese Association for Maternal and Child Health
Zhejiang Da Xue Xue Bao Yi Xue Ban 2022 Feb 25;51(1):122-128. doi: 10.3724/zdxbyxb-2022-0107. PMID: 36161784Free PMC Article
Epigenetics and obesity cardiomyopathy: From pathophysiology to prevention and management.
Zhang Y, Ren J
Pharmacol Ther 2016 May;161:52-66. Epub 2016 Mar 22 doi: 10.1016/j.pharmthera.2016.03.005. PMID: 27013344
Cause and management of muscle wasting in chronic liver disease.
Dasarathy S
Curr Opin Gastroenterol 2016 May;32(3):159-65. doi: 10.1097/MOG.0000000000000261. PMID: 26974417Free PMC Article

Recent clinical studies

Etiology

Favorable liver and skeletal muscle changes in patients with MASLD and T2DM receiving glucagon-like peptide-1 receptor agonist: A prospective cohort study.
Kakegawa T, Sugimoto K, Saito K, Yunaiyama D, Araki Y, Wada T, Takahashi H, Yoshimasu Y, Takeuchi H, Itoi T
Medicine (Baltimore) 2024 Jun 7;103(23):e38444. doi: 10.1097/MD.0000000000038444. PMID: 38847728Free PMC Article
Supplementation with branched-chain amino acids ameliorates hypoalbuminemia, prevents sarcopenia, and reduces fat accumulation in the skeletal muscles of patients with liver cirrhosis.
Kitajima Y, Takahashi H, Akiyama T, Murayama K, Iwane S, Kuwashiro T, Tanaka K, Kawazoe S, Ono N, Eguchi T, Anzai K, Eguchi Y
J Gastroenterol 2018 Mar;53(3):427-437. Epub 2017 Jul 24 doi: 10.1007/s00535-017-1370-x. PMID: 28741271
Age-related fat deposition in multifidus muscle could be a marker for nonalcoholic fatty liver disease.
Kitajima Y, Eguchi Y, Ishibashi E, Nakashita S, Aoki S, Toda S, Mizuta T, Ozaki I, Ono N, Eguchi T, Arai K, Iwakiri R, Fujimoto K
J Gastroenterol 2010 Feb;45(2):218-24. Epub 2009 Nov 3 doi: 10.1007/s00535-009-0147-2. PMID: 19882375

Diagnosis

Supplementation with branched-chain amino acids ameliorates hypoalbuminemia, prevents sarcopenia, and reduces fat accumulation in the skeletal muscles of patients with liver cirrhosis.
Kitajima Y, Takahashi H, Akiyama T, Murayama K, Iwane S, Kuwashiro T, Tanaka K, Kawazoe S, Ono N, Eguchi T, Anzai K, Eguchi Y
J Gastroenterol 2018 Mar;53(3):427-437. Epub 2017 Jul 24 doi: 10.1007/s00535-017-1370-x. PMID: 28741271

Therapy

Favorable liver and skeletal muscle changes in patients with MASLD and T2DM receiving glucagon-like peptide-1 receptor agonist: A prospective cohort study.
Kakegawa T, Sugimoto K, Saito K, Yunaiyama D, Araki Y, Wada T, Takahashi H, Yoshimasu Y, Takeuchi H, Itoi T
Medicine (Baltimore) 2024 Jun 7;103(23):e38444. doi: 10.1097/MD.0000000000038444. PMID: 38847728Free PMC Article
Supplementation with branched-chain amino acids ameliorates hypoalbuminemia, prevents sarcopenia, and reduces fat accumulation in the skeletal muscles of patients with liver cirrhosis.
Kitajima Y, Takahashi H, Akiyama T, Murayama K, Iwane S, Kuwashiro T, Tanaka K, Kawazoe S, Ono N, Eguchi T, Anzai K, Eguchi Y
J Gastroenterol 2018 Mar;53(3):427-437. Epub 2017 Jul 24 doi: 10.1007/s00535-017-1370-x. PMID: 28741271

Prognosis

Supplementation with branched-chain amino acids ameliorates hypoalbuminemia, prevents sarcopenia, and reduces fat accumulation in the skeletal muscles of patients with liver cirrhosis.
Kitajima Y, Takahashi H, Akiyama T, Murayama K, Iwane S, Kuwashiro T, Tanaka K, Kawazoe S, Ono N, Eguchi T, Anzai K, Eguchi Y
J Gastroenterol 2018 Mar;53(3):427-437. Epub 2017 Jul 24 doi: 10.1007/s00535-017-1370-x. PMID: 28741271

Supplemental Content

Table of contents

    Clinical resources

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