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EBV positive mucocutaneous ulcer

MedGen UID:
1385652
Concept ID:
C4324739
Disease or Syndrome
Synonyms: EBV-Positive Mucocutaneous Ulcer; Epstein Barr virus positive mucocutaneous ulcer; Epstein-Barr Virus-Positive Mucocutaneous Ulcer
SNOMED CT: EBV positive mucocutaneous ulcer (788572005); Epstein Barr virus positive mucocutaneous ulcer (788572005)

Definition

A rare Epstein-Barr virus-positive B-cell lymphoproliferative disorder which presents as an ulcerative mucocutaneous lesion. It is associated with immune suppression, including age-related and drug-induced immunosuppression. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEBV positive mucocutaneous ulcer

Professional guidelines

PubMed

Sohani AR
Surg Pathol Clin 2023 Jun;16(2):287-346. Epub 2023 Mar 30 doi: 10.1016/j.path.2023.02.002. PMID: 37149361

Recent clinical studies

Etiology

Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Willemze R
Presse Med 2022 Mar;51(1):104126. Epub 2022 May 13 doi: 10.1016/j.lpm.2022.104126. PMID: 35569698
Fujimoto M, Kaku Y, Hirata M, Usui S, Yamada Y, Haga H
Am J Surg Pathol 2021 May 1;45(5):694-700. doi: 10.1097/PAS.0000000000001661. PMID: 33739792
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Goodlad JR
Surg Pathol Clin 2017 Jun;10(2):429-453. Epub 2017 Mar 18 doi: 10.1016/j.path.2017.01.001. PMID: 28477890

Diagnosis

Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Sukswai N, Lyapichev K, Khoury JD, Medeiros LJ
Pathology 2020 Jan;52(1):53-67. Epub 2019 Nov 15 doi: 10.1016/j.pathol.2019.08.013. PMID: 31735345
Ikeda T, Gion Y, Yoshino T, Sato Y
J Clin Exp Hematop 2019;59(2):64-71. doi: 10.3960/jslrt.18039. PMID: 31257347Free PMC Article
Kempf W, Zimmermann AK, Mitteldorf C
Hematol Oncol 2019 Jun;37 Suppl 1:43-47. doi: 10.1002/hon.2584. PMID: 31187534

Therapy

Sawada K, Momose S, Iijima Y, Takahashi T, Kaneko T, Yamamoto W, Yamashita T, Higashi M, Kizaki M, Tamaru JI
J Clin Exp Hematop 2023 Jun 28;63(2):90-98. Epub 2023 May 28 doi: 10.3960/jslrt.22048. PMID: 37245972Free PMC Article
Fernández-Gordón Sánchez FM, Arranz Álvarez M, Jiménez Almonacid J, García-Ramos García C
Rev Esp Enferm Dig 2022 Jan;114(1):49. doi: 10.17235/reed.2021.8245/2021. PMID: 34470456
Fujimoto M, Kaku Y, Hirata M, Usui S, Yamada Y, Haga H
Am J Surg Pathol 2021 May 1;45(5):694-700. doi: 10.1097/PAS.0000000000001661. PMID: 33739792
Ikeda T, Gion Y, Sakamoto M, Tachibana T, Nishikori A, Nishimura MF, Yoshino T, Sato Y
Mod Pathol 2020 Dec;33(12):2437-2448. Epub 2020 Jun 19 doi: 10.1038/s41379-020-0599-8. PMID: 32561847
McGinness JL, Spicknall KE, Mutasim DF
J Cutan Pathol 2012 Mar;39(3):377-81. Epub 2012 Jan 11 doi: 10.1111/j.1600-0560.2011.01829.x. PMID: 22236092

Prognosis

Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Ikeda T, Gion Y, Nishimura Y, Nishimura MF, Yoshino T, Sato Y
Int J Mol Sci 2021 Jan 21;22(3) doi: 10.3390/ijms22031053. PMID: 33494358Free PMC Article
Ikeda T, Gion Y, Yoshino T, Sato Y
J Clin Exp Hematop 2019;59(2):64-71. doi: 10.3960/jslrt.18039. PMID: 31257347Free PMC Article
Kempf W, Zimmermann AK, Mitteldorf C
Hematol Oncol 2019 Jun;37 Suppl 1:43-47. doi: 10.1002/hon.2584. PMID: 31187534
McGinness JL, Spicknall KE, Mutasim DF
J Cutan Pathol 2012 Mar;39(3):377-81. Epub 2012 Jan 11 doi: 10.1111/j.1600-0560.2011.01829.x. PMID: 22236092

Clinical prediction guides

Fujimoto M, Kaku Y, Hirata M, Usui S, Yamada Y, Haga H
Am J Surg Pathol 2021 May 1;45(5):694-700. doi: 10.1097/PAS.0000000000001661. PMID: 33739792
Ikeda T, Gion Y, Sakamoto M, Tachibana T, Nishikori A, Nishimura MF, Yoshino T, Sato Y
Mod Pathol 2020 Dec;33(12):2437-2448. Epub 2020 Jun 19 doi: 10.1038/s41379-020-0599-8. PMID: 32561847
Gali V, Bleeker JS, Lynch D
S D Med 2018 Jun;71(6):252-255. PMID: 30005148
Daroontum T, Kohno K, Eladl AE, Satou A, Sakakibara A, Matsukage S, Yakushiji N, Ya-In C, Nakamura S, Asano N, Kato S
Histopathology 2018 Jun;72(7):1115-1127. Epub 2018 Mar 7 doi: 10.1111/his.13464. PMID: 29314151
Hart M, Thakral B, Yohe S, Balfour HH Jr, Singh C, Spears M, McKenna RW
Am J Surg Pathol 2014 Nov;38(11):1522-9. doi: 10.1097/PAS.0000000000000282. PMID: 25007145

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