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Iatrogenic Hypoparathyroidism

MedGen UID:
1387268
•Concept ID:
C4330470
•
Disease or Syndrome

Definition

Hypoparathyroidism resulting from medical treatment or intervention. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIatrogenic Hypoparathyroidism

Professional guidelines

PubMed

Clinic Heterogeneity and Management of Pediatric Patients With Germline RET Proto-oncogene Mutation: Single-center Experience.
Şıklar Z, Kontbay T, Dincaslan H, Ünal E, Berberoglu M
J Pediatr Hematol Oncol 2023 Oct 1;45(7):e789-e797. Epub 2023 Jul 24 doi: 10.1097/MPH.0000000000002728. PMID: 37526376
Cultured parathyroid cells allotransplantation without immunosuppression for treatment of intractable hypoparathyroidism.
Tołłoczko T, Woźniewicz B, Górski A, Sawicki A, Nawrot I, Migaj M, Zawitkowska T
Ann Transplant 1996;1(1):51-3. PMID: 9869939

Recent clinical studies

Etiology

The anatomical basis for preserving the blood supply to the parathyroids during thyroid surgery, and a review of current technologic advances.
Shaari AL, Spaulding SL, Xing MH, Yue LE, Machado RA, Moubayed SP, Mundi N, Chai RL, Urken ML
Am J Otolaryngol 2022 Jan-Feb;43(1):103161. Epub 2021 Jul 30 doi: 10.1016/j.amjoto.2021.103161. PMID: 34375794
Iatrogenic hypoparathyroidism after surgery for retrosternal goitre. A single centre retrospective analysis.
Damiano G, Cocchiara G, Palumbo VD, Fatica F, Caternicchia F, Lo Monte AI, Cajozzo M
Clin Ter 2018 Mar-Apr;169(2):e67-e70. doi: 10.7417/T.2018.2056. PMID: 29595868
Protracted hypocalcemia following post-thyroidectomy lumbar rhabdomyolysis secondary to evolving hypoparathyroidism.
Cheema UY, Vogler CN, Thompson J, Sattovia SL, Vallurupalli S
Ear Nose Throat J 2015 Mar;94(3):113-6. PMID: 25738717

Diagnosis

Severe reversible hypocalcemic cardiomyopathy diagnosed 36 years after subtotal thyroidectomy - a case report.
Elikowski W, Małek-Elikowska M, Lachowska-Kotowska P
Pol Merkur Lekarski 2017 Jul 21;43(253):26-31. PMID: 28805198
Hypocalcemic generalised seizures as a manifestation of iatrogenic hypoparathyroidism months to years after thyroid surgery.
Mrowka M, Knake S, Klinge H, Odin P, Rosenow F
Epileptic Disord 2004 Jun;6(2):85-7. PMID: 15246952
Diagnostic and therapeutic aspects of iatrogenic hypoparathyroidism.
Pallotti F, Seregni E, Ferrari L, Martinetti A, Biancolini D, Bombardieri E
Tumori 2003 Sep-Oct;89(5):547-9. doi: 10.1177/030089160308900519. PMID: 14870783

Therapy

The anatomical basis for preserving the blood supply to the parathyroids during thyroid surgery, and a review of current technologic advances.
Shaari AL, Spaulding SL, Xing MH, Yue LE, Machado RA, Moubayed SP, Mundi N, Chai RL, Urken ML
Am J Otolaryngol 2022 Jan-Feb;43(1):103161. Epub 2021 Jul 30 doi: 10.1016/j.amjoto.2021.103161. PMID: 34375794
Iatrogenic hypoparathyroidism after surgery for retrosternal goitre. A single centre retrospective analysis.
Damiano G, Cocchiara G, Palumbo VD, Fatica F, Caternicchia F, Lo Monte AI, Cajozzo M
Clin Ter 2018 Mar-Apr;169(2):e67-e70. doi: 10.7417/T.2018.2056. PMID: 29595868
Severe reversible hypocalcemic cardiomyopathy diagnosed 36 years after subtotal thyroidectomy - a case report.
Elikowski W, Małek-Elikowska M, Lachowska-Kotowska P
Pol Merkur Lekarski 2017 Jul 21;43(253):26-31. PMID: 28805198
Protracted hypocalcemia following post-thyroidectomy lumbar rhabdomyolysis secondary to evolving hypoparathyroidism.
Cheema UY, Vogler CN, Thompson J, Sattovia SL, Vallurupalli S
Ear Nose Throat J 2015 Mar;94(3):113-6. PMID: 25738717
Diagnostic and therapeutic aspects of iatrogenic hypoparathyroidism.
Pallotti F, Seregni E, Ferrari L, Martinetti A, Biancolini D, Bombardieri E
Tumori 2003 Sep-Oct;89(5):547-9. doi: 10.1177/030089160308900519. PMID: 14870783

Prognosis

Iatrogenic hypoparathyroidism after surgery for retrosternal goitre. A single centre retrospective analysis.
Damiano G, Cocchiara G, Palumbo VD, Fatica F, Caternicchia F, Lo Monte AI, Cajozzo M
Clin Ter 2018 Mar-Apr;169(2):e67-e70. doi: 10.7417/T.2018.2056. PMID: 29595868
Anterior mediastinal tracheostomy with and without cervical exenteration.
Orringer MB
Ann Thorac Surg 1992 Oct;54(4):628-36; discussion 636-7. doi: 10.1016/0003-4975(92)91005-t. PMID: 1417219

Clinical prediction guides

Iatrogenic hypoparathyroidism after surgery for retrosternal goitre. A single centre retrospective analysis.
Damiano G, Cocchiara G, Palumbo VD, Fatica F, Caternicchia F, Lo Monte AI, Cajozzo M
Clin Ter 2018 Mar-Apr;169(2):e67-e70. doi: 10.7417/T.2018.2056. PMID: 29595868

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