U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ejection Systolic Heart Murmur

MedGen UID:
1389228
•Concept ID:
C0694547
•
Finding
Synonym: Systolic ejection murmur

Definition

A heart murmur that occurs predominantly in midsystole, when ejection volume and velocity of blood flow are at their maximum; it is produced by ejection of blood into the pulmonary artery and aorta. It is typically crescendo-decrescendo. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEjection Systolic Heart Murmur

Professional guidelines

PubMed

A review of the pathophysiology, diagnosis, and treatment of aortic valve stenosis in elderly patients.
Aronow WS
Hosp Pract (1995) 2013 Oct-Nov;41(4):66-77. doi: 10.3810/hp.2013.10.1082. PMID: 24145591
Diagnosis and management of acyanotic heart disease: part II -- left-to-right shunt lesions.
Syamasundar Rao P
Indian J Pediatr 2005 Jun;72(6):503-12. doi: 10.1007/BF02724429. PMID: 15985740
Diagnosis and management of acyanotic heart disease: part I -- obstructive lesions.
Syamasundar Rao P
Indian J Pediatr 2005 Jun;72(6):496-502. PMID: 15985739

Recent clinical studies

Etiology

Does Iron Deficiency Affect the Heart in Children?
Demir F, Kayali S, Gokcebay DG
J Pediatr Hematol Oncol 2022 Apr 1;44(3):84-88. doi: 10.1097/MPH.0000000000002170. PMID: 33843814
Accidental Heart Murmurs.
Begic E, Begic Z
Med Arch 2017 Aug;71(4):284-287. doi: 10.5455/medarh.2017.71.284-287. PMID: 28974851Free PMC Article
Systolic ejection click versus split first heart sound: Are our ears deceiving us?
Hoeting NM, McCracken CE, McConnell M, Sallee D, Iannucci GJ, Oster ME
Congenit Heart Dis 2017 Jul;12(4):417-420. Epub 2017 Mar 16 doi: 10.1111/chd.12460. PMID: 28299882
Aortic stenosis.
Aronow WS
Compr Ther 2007 Winter;33(4):174-83. doi: 10.1007/s12019-007-8021-8. PMID: 18025609
Valvular aortic stenosis in the elderly.
Aronow WS
Cardiol Rev 2007 Sep-Oct;15(5):217-25. doi: 10.1097/CRD.0b013e31805f6796. PMID: 17700380

Diagnosis

Murmurs other than the early diastolic murmur in aortic dissection.
Jolobe OMP
Am J Emerg Med 2021 Nov;49:133-136. Epub 2021 May 21 doi: 10.1016/j.ajem.2021.05.041. PMID: 34102459
Accidental Heart Murmurs.
Begic E, Begic Z
Med Arch 2017 Aug;71(4):284-287. doi: 10.5455/medarh.2017.71.284-287. PMID: 28974851Free PMC Article
Aortic stenosis.
Aronow WS
Compr Ther 2007 Winter;33(4):174-83. doi: 10.1007/s12019-007-8021-8. PMID: 18025609
Cardiac pearls.
Harvey WP
Dis Mon 1994 Feb;40(2):41-113. doi: 10.1016/0011-5029(94)90002-7. PMID: 8306847
Mitral valve regurgitation.
O'Rourke RA, Crawford MH
Curr Probl Cardiol 1984 May;9(2):1-52. doi: 10.1016/0146-2806(84)90021-5. PMID: 6375982

Therapy

A review of the pathophysiology, diagnosis, and treatment of aortic valve stenosis in elderly patients.
Aronow WS
Hosp Pract (1995) 2013 Oct-Nov;41(4):66-77. doi: 10.3810/hp.2013.10.1082. PMID: 24145591
Aortic stenosis.
Aronow WS
Compr Ther 2007 Winter;33(4):174-83. doi: 10.1007/s12019-007-8021-8. PMID: 18025609
Valvular aortic stenosis in the elderly.
Aronow WS
Cardiol Rev 2007 Sep-Oct;15(5):217-25. doi: 10.1097/CRD.0b013e31805f6796. PMID: 17700380
Cardiac pearls.
Harvey WP
Dis Mon 1994 Feb;40(2):41-113. doi: 10.1016/0011-5029(94)90002-7. PMID: 8306847
Mitral valve regurgitation.
O'Rourke RA, Crawford MH
Curr Probl Cardiol 1984 May;9(2):1-52. doi: 10.1016/0146-2806(84)90021-5. PMID: 6375982

Prognosis

Postsystolic shortening and early systolic lengthening for early detection of myocardial involvement in patients with systemic lupus erythematosus.
Wan M, Liu D, Zhang P, Xie P, Liang L, He W
Echocardiography 2022 Oct;39(10):1284-1290. Epub 2022 Sep 8 doi: 10.1111/echo.15442. PMID: 36074004
Does Iron Deficiency Affect the Heart in Children?
Demir F, Kayali S, Gokcebay DG
J Pediatr Hematol Oncol 2022 Apr 1;44(3):84-88. doi: 10.1097/MPH.0000000000002170. PMID: 33843814
Acute Tachycardia-Induced Cardiomyopathy: A Case Report.
Amr M
Am J Case Rep 2021 May 10;22:e930732. doi: 10.12659/AJCR.930732. PMID: 33970894Free PMC Article
Cardiac abnormalities in birth asphyxia.
Ranjit MS
Indian J Pediatr 2000 Mar;67(3 Suppl):S26-9. PMID: 11129917
Mitral valve regurgitation.
O'Rourke RA, Crawford MH
Curr Probl Cardiol 1984 May;9(2):1-52. doi: 10.1016/0146-2806(84)90021-5. PMID: 6375982

Clinical prediction guides

Postsystolic shortening and early systolic lengthening for early detection of myocardial involvement in patients with systemic lupus erythematosus.
Wan M, Liu D, Zhang P, Xie P, Liang L, He W
Echocardiography 2022 Oct;39(10):1284-1290. Epub 2022 Sep 8 doi: 10.1111/echo.15442. PMID: 36074004
Does Iron Deficiency Affect the Heart in Children?
Demir F, Kayali S, Gokcebay DG
J Pediatr Hematol Oncol 2022 Apr 1;44(3):84-88. doi: 10.1097/MPH.0000000000002170. PMID: 33843814
Screening for aortic stenosis using physical examination and echocardiography.
Abe Y
J Echocardiogr 2021 Jun;19(2):80-85. Epub 2021 Jan 7 doi: 10.1007/s12574-020-00511-8. PMID: 33415574
Systolic ejection click versus split first heart sound: Are our ears deceiving us?
Hoeting NM, McCracken CE, McConnell M, Sallee D, Iannucci GJ, Oster ME
Congenit Heart Dis 2017 Jul;12(4):417-420. Epub 2017 Mar 16 doi: 10.1111/chd.12460. PMID: 28299882
Cardiac pearls.
Harvey WP
Dis Mon 1994 Feb;40(2):41-113. doi: 10.1016/0011-5029(94)90002-7. PMID: 8306847

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...