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Nasal cavity cancer

MedGen UID:
152601
•Concept ID:
C0728864
•
Neoplastic Process
Synonyms: cancer of nasal cavity; Malignant Nasal Cavity Neoplasm; malignant nasal cavity neoplasm; Malignant Nasal Cavity Tumor; malignant nasal cavity tumor; malignant nasal cavity tumour; Malignant neoplasm of nasal cavities; malignant neoplasm of nasal cavities; Malignant Neoplasm of Nasal Cavity; malignant neoplasm of nasal cavity; Malignant Neoplasm of the Nasal Cavity; malignant neoplasm of the nasal cavity; Malignant tumor of nasal cavity; Malignant Tumor of Nasal Cavity; malignant tumor of nasal cavity; Malignant Tumor of the Nasal Cavity; malignant tumor of the nasal cavity; malignant tumour of nasal cavity; malignant tumour of the nasal cavity; nasal cavity cancer
SNOMED CT: Malignant neoplasm of nasal cavities (363422006); Malignant tumor of nasal cavity (363422006)
 
Monarch Initiative: MONDO:0001128

Definition

A malignant neoplasm affecting the nasal cavity. Representative examples include carcinoma and lymphoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasal cavity cancer

Professional guidelines

PubMed

Nasal Cavity Squamous Cell Carcinoma: Factors Associated With Treatment Outcomes and Potential Organ Preservation.
Issa K, Teitelbaum J, Smith BD, Wang F, Ackall F, Sargi Z, Rangarajan SV, Jung SH, Jang DW, Abi Hachem R
Am J Rhinol Allergy 2023 Jan;37(1):35-42. Epub 2022 Oct 2 doi: 10.1177/19458924221130133. PMID: 36189818
Primary surgical treatment of nasal vestibule cancer - therapeutic outcome and reconstructive strategies.
Zaoui K, Plinkert PK, Federspil PA
Rhinology 2018 Dec 1;56(4):393-399. doi: 10.4193/Rhin17.157. PMID: 30098234
ACR appropriateness criteria(®) nasal cavity and paranasal sinus cancers.
Siddiqui F, Smith RV, Yom SS, Beitler JJ, Busse PM, Cooper JS, Hanna EY, Jones CU, Koyfman SA, Quon H, Ridge JA, Saba NF, Worden F, Yao M, Salama JK; Expert Panel on Radiation Oncology - Head and Neck Cancer
Head Neck 2017 Mar;39(3):407-418. Epub 2016 Dec 29 doi: 10.1002/hed.24639. PMID: 28032679

Recent clinical studies

Etiology

Nasal Cavity Squamous Cell Carcinoma: Factors Associated With Treatment Outcomes and Potential Organ Preservation.
Issa K, Teitelbaum J, Smith BD, Wang F, Ackall F, Sargi Z, Rangarajan SV, Jung SH, Jang DW, Abi Hachem R
Am J Rhinol Allergy 2023 Jan;37(1):35-42. Epub 2022 Oct 2 doi: 10.1177/19458924221130133. PMID: 36189818
The changing face of Irish head and neck cancer epidemiology: 20 years of data.
Sexton GP, Walsh P, Moriarty F, O'Neill JP
Eur Arch Otorhinolaryngol 2022 Jun;279(6):3079-3088. Epub 2021 Oct 13 doi: 10.1007/s00405-021-07118-4. PMID: 34647138Free PMC Article
Conditional and Overall Disease-Specific Survival in Patients With Paranasal Sinus and Nasal Cavity Cancer: Improved Outcomes in the Endoscopic Era.
Sharma RK, Irace AL, Schlosser RJ, Overdevest JB, Rowan NR, Troob SH, Gudis DA
Am J Rhinol Allergy 2022 Jan;36(1):57-64. Epub 2021 May 17 doi: 10.1177/19458924211019158. PMID: 34000835
Cancer patterns in nasopharyngeal carcinoma multiplex families over 15 years.
Yu KJ, Hsu WL, Chiang CJ, Chen TC, Liu Z, Lou PJ, Diehl S, Goldstein AM, Chen CJ, Wang CP, Hildesheim A
Cancer 2021 Nov 15;127(22):4171-4176. Epub 2021 Jul 29 doi: 10.1002/cncr.33799. PMID: 34324707
ACR appropriateness criteria(®) nasal cavity and paranasal sinus cancers.
Siddiqui F, Smith RV, Yom SS, Beitler JJ, Busse PM, Cooper JS, Hanna EY, Jones CU, Koyfman SA, Quon H, Ridge JA, Saba NF, Worden F, Yao M, Salama JK; Expert Panel on Radiation Oncology - Head and Neck Cancer
Head Neck 2017 Mar;39(3):407-418. Epub 2016 Dec 29 doi: 10.1002/hed.24639. PMID: 28032679

Diagnosis

Nasal Cavity Squamous Cell Carcinoma: Factors Associated With Treatment Outcomes and Potential Organ Preservation.
Issa K, Teitelbaum J, Smith BD, Wang F, Ackall F, Sargi Z, Rangarajan SV, Jung SH, Jang DW, Abi Hachem R
Am J Rhinol Allergy 2023 Jan;37(1):35-42. Epub 2022 Oct 2 doi: 10.1177/19458924221130133. PMID: 36189818
Conditional and Overall Disease-Specific Survival in Patients With Paranasal Sinus and Nasal Cavity Cancer: Improved Outcomes in the Endoscopic Era.
Sharma RK, Irace AL, Schlosser RJ, Overdevest JB, Rowan NR, Troob SH, Gudis DA
Am J Rhinol Allergy 2022 Jan;36(1):57-64. Epub 2021 May 17 doi: 10.1177/19458924211019158. PMID: 34000835
Cost-effectiveness analysis of proton beam therapy for treatment decision making in paranasal sinus and nasal cavity cancers in China.
Li G, Qiu B, Huang YX, Doyen J, Bondiau PY, Benezery K, Xia YF, Qian CN
BMC Cancer 2020 Jun 26;20(1):599. doi: 10.1186/s12885-020-07083-x. PMID: 32590957Free PMC Article
Primary surgical treatment of nasal vestibule cancer - therapeutic outcome and reconstructive strategies.
Zaoui K, Plinkert PK, Federspil PA
Rhinology 2018 Dec 1;56(4):393-399. doi: 10.4193/Rhin17.157. PMID: 30098234
Nasal cavity reirradiation: a challenging case for comparison between proton therapy and volumetric modulated arc therapy.
Ruggieri R, Dionisi F, Mazzola R, Fellin F, Fiorentino A, Schwarz M, Ricchetti F, Amichetti M, Alongi F
Tumori 2016 Nov 11;102(Suppl. 2) doi: 10.5301/tj.5000375. PMID: 26166226

Therapy

Cost-effectiveness analysis of proton beam therapy for treatment decision making in paranasal sinus and nasal cavity cancers in China.
Li G, Qiu B, Huang YX, Doyen J, Bondiau PY, Benezery K, Xia YF, Qian CN
BMC Cancer 2020 Jun 26;20(1):599. doi: 10.1186/s12885-020-07083-x. PMID: 32590957Free PMC Article
The use of photodynamic therapy as adjuvant therapy to surgery in recurrent malignant tumors of the paranasal sinuses.
Caesar L, van Doeveren TE, Tan IB, Dilci A, van Veen RL, Karakullukcu B
Photodiagnosis Photodyn Ther 2015 Sep;12(3):414-21. Epub 2015 Jun 10 doi: 10.1016/j.pdpdt.2015.06.001. PMID: 26072296
Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting--the MSKCC experience.
Hoppe BS, Stegman LD, Zelefsky MJ, Rosenzweig KE, Wolden SL, Patel SG, Shah JP, Kraus DH, Lee NY
Int J Radiat Oncol Biol Phys 2007 Mar 1;67(3):691-702. Epub 2006 Dec 8 doi: 10.1016/j.ijrobp.2006.09.023. PMID: 17161557
Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
Kim CH, Song KS, Kim KS, Kim JY, Lee BJ, Lee JG, Yoon JH
Acta Otolaryngol 2005 Feb;125(2):201-6. doi: 10.1080/00016480410020293. PMID: 15880954
Paranasal sinuses and nasal cavity cancer: different radiotherapeutic options, results and late damages.
Olmi P, Cellai E, Chiavacci A, Fallai C
Tumori 1986 Dec 31;72(6):589-95. doi: 10.1177/030089168607200609. PMID: 3810867

Prognosis

Nasal Cavity Squamous Cell Carcinoma: Factors Associated With Treatment Outcomes and Potential Organ Preservation.
Issa K, Teitelbaum J, Smith BD, Wang F, Ackall F, Sargi Z, Rangarajan SV, Jung SH, Jang DW, Abi Hachem R
Am J Rhinol Allergy 2023 Jan;37(1):35-42. Epub 2022 Oct 2 doi: 10.1177/19458924221130133. PMID: 36189818
The changing face of Irish head and neck cancer epidemiology: 20 years of data.
Sexton GP, Walsh P, Moriarty F, O'Neill JP
Eur Arch Otorhinolaryngol 2022 Jun;279(6):3079-3088. Epub 2021 Oct 13 doi: 10.1007/s00405-021-07118-4. PMID: 34647138Free PMC Article
Conditional and Overall Disease-Specific Survival in Patients With Paranasal Sinus and Nasal Cavity Cancer: Improved Outcomes in the Endoscopic Era.
Sharma RK, Irace AL, Schlosser RJ, Overdevest JB, Rowan NR, Troob SH, Gudis DA
Am J Rhinol Allergy 2022 Jan;36(1):57-64. Epub 2021 May 17 doi: 10.1177/19458924211019158. PMID: 34000835
ACR appropriateness criteria(®) nasal cavity and paranasal sinus cancers.
Siddiqui F, Smith RV, Yom SS, Beitler JJ, Busse PM, Cooper JS, Hanna EY, Jones CU, Koyfman SA, Quon H, Ridge JA, Saba NF, Worden F, Yao M, Salama JK; Expert Panel on Radiation Oncology - Head and Neck Cancer
Head Neck 2017 Mar;39(3):407-418. Epub 2016 Dec 29 doi: 10.1002/hed.24639. PMID: 28032679
Cancer of the nasal cavity: survival and factors influencing prognosis.
Bhattacharyya N
Arch Otolaryngol Head Neck Surg 2002 Sep;128(9):1079-83. doi: 10.1001/archotol.128.9.1079. PMID: 12220216

Clinical prediction guides

Nasal Cavity Squamous Cell Carcinoma: Factors Associated With Treatment Outcomes and Potential Organ Preservation.
Issa K, Teitelbaum J, Smith BD, Wang F, Ackall F, Sargi Z, Rangarajan SV, Jung SH, Jang DW, Abi Hachem R
Am J Rhinol Allergy 2023 Jan;37(1):35-42. Epub 2022 Oct 2 doi: 10.1177/19458924221130133. PMID: 36189818
Cancer patterns in nasopharyngeal carcinoma multiplex families over 15 years.
Yu KJ, Hsu WL, Chiang CJ, Chen TC, Liu Z, Lou PJ, Diehl S, Goldstein AM, Chen CJ, Wang CP, Hildesheim A
Cancer 2021 Nov 15;127(22):4171-4176. Epub 2021 Jul 29 doi: 10.1002/cncr.33799. PMID: 34324707
Are Intraoral Stents Effective for Reducing the Severity of Oral Mucositis During Radiotherapy for Maxillary and Nasal Cavity Cancer?
Inoue Y, Yamagata K, Nakamura M, Ohnishi K, Tabuchi K, Bukawa H
J Oral Maxillofac Surg 2020 Jul;78(7):1214.e1-1214.e8. Epub 2020 Feb 13 doi: 10.1016/j.joms.2020.02.009. PMID: 32165135
Molecular characterization of cancers with NTRK gene fusions.
Gatalica Z, Xiu J, Swensen J, Vranic S
Mod Pathol 2019 Jan;32(1):147-153. Epub 2018 Aug 31 doi: 10.1038/s41379-018-0118-3. PMID: 30171197
Cancer of the nasal cavity: survival and factors influencing prognosis.
Bhattacharyya N
Arch Otolaryngol Head Neck Surg 2002 Sep;128(9):1079-83. doi: 10.1001/archotol.128.9.1079. PMID: 12220216

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