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Somatosensory Disorders

MedGen UID:
156044
•Concept ID:
C0752262
•
Disease or Syndrome
Synonyms: Sensation Disorder, Somatic; Sensation Disorders, Somatic; Somatic Sensation Disorder; Somatic Sensation Disorders; Somatosensory Disorder

Definition

Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation. [from MeSH]

Professional guidelines

PubMed

Mechanisms, diagnosis, prevention and management of perioperative opioid-induced hyperalgesia.
Wilson SH, Hellman KM, James D, Adler AC, Chandrakantan A
Pain Manag 2021 Apr;11(4):405-417. Epub 2021 Mar 29 doi: 10.2217/pmt-2020-0105. PMID: 33779215Free PMC Article
Changing practice in the assessment and treatment of somatosensory loss in stroke survivors: protocol for a knowledge translation study.
Cahill LS, Lannin NA, Mak-Yuen YYK, Turville ML, Carey LM
BMC Health Serv Res 2018 Jan 23;18(1):34. doi: 10.1186/s12913-018-2829-z. PMID: 29361937Free PMC Article
Somatosensory assessment and treatment after stroke: An evidence-practice gap.
Pumpa LU, Cahill LS, Carey LM
Aust Occup Ther J 2015 Apr;62(2):93-104. Epub 2015 Jan 23 doi: 10.1111/1440-1630.12170. PMID: 25615889

Recent clinical studies

Etiology

Effect of Graded Sensorimotor Retraining on Pain Intensity in Patients With Chronic Low Back Pain: A Randomized Clinical Trial.
Bagg MK, Wand BM, Cashin AG, Lee H, Hübscher M, Stanton TR, O'Connell NE, O'Hagan ET, Rizzo RRN, Wewege MA, Rabey M, Goodall S, Saing S, Lo SN, Luomajoki H, Herbert RD, Maher CG, Moseley GL, McAuley JH
JAMA 2022 Aug 2;328(5):430-439. doi: 10.1001/jama.2022.9930. PMID: 35916848Free PMC Article
Insula stroke: the weird and the worrisome.
Raghu ALB, Parker T, van Wyk A, Green AL
Postgrad Med J 2019 Sep;95(1127):497-504. Epub 2019 Jul 11 doi: 10.1136/postgradmedj-2019-136732. PMID: 31296791
Long-term effects of neonatal pain.
Walker SM
Semin Fetal Neonatal Med 2019 Aug;24(4):101005. Epub 2019 Apr 5 doi: 10.1016/j.siny.2019.04.005. PMID: 30987942
Sensory processing in children with and without autism: a comparative study using the short sensory profile.
Tomchek SD, Dunn W
Am J Occup Ther 2007 Mar-Apr;61(2):190-200. doi: 10.5014/ajot.61.2.190. PMID: 17436841
Preventing foot ulcers in patients with diabetes.
Singh N, Armstrong DG, Lipsky BA
JAMA 2005 Jan 12;293(2):217-28. doi: 10.1001/jama.293.2.217. PMID: 15644549

Diagnosis

Nociplastic pain: towards an understanding of prevalent pain conditions.
Fitzcharles MA, Cohen SP, Clauw DJ, Littlejohn G, Usui C, Häuser W
Lancet 2021 May 29;397(10289):2098-2110. doi: 10.1016/S0140-6736(21)00392-5. PMID: 34062144
Sensory syndromes.
Klingner CM, Witte OW, Günther A
Front Neurol Neurosci 2012;30:4-8. Epub 2012 Feb 14 doi: 10.1159/000333373. PMID: 22377851
Concept evolution in sensory integration: a proposed nosology for diagnosis.
Miller LJ, Anzalone ME, Lane SJ, Cermak SA, Osten ET
Am J Occup Ther 2007 Mar-Apr;61(2):135-40. doi: 10.5014/ajot.61.2.135. PMID: 17436834
Preventing foot ulcers in patients with diabetes.
Singh N, Armstrong DG, Lipsky BA
JAMA 2005 Jan 12;293(2):217-28. doi: 10.1001/jama.293.2.217. PMID: 15644549
Genioplasty.
Stanton DC
Facial Plast Surg 2003 Feb;19(1):75-86. doi: 10.1055/s-2003-39130. PMID: 12739183

Therapy

Interventions for perceptual disorders following stroke.
Hazelton C, Thomson K, Todhunter-Brown A, Campbell P, Chung CS, Dorris L, Gillespie DC, Hunter SM, McGill K, Nicolson DJ, Williams LJ, Brady MC
Cochrane Database Syst Rev 2022 Nov 3;11(11):CD007039. doi: 10.1002/14651858.CD007039.pub3. PMID: 36326118Free PMC Article
Effect of Graded Sensorimotor Retraining on Pain Intensity in Patients With Chronic Low Back Pain: A Randomized Clinical Trial.
Bagg MK, Wand BM, Cashin AG, Lee H, Hübscher M, Stanton TR, O'Connell NE, O'Hagan ET, Rizzo RRN, Wewege MA, Rabey M, Goodall S, Saing S, Lo SN, Luomajoki H, Herbert RD, Maher CG, Moseley GL, McAuley JH
JAMA 2022 Aug 2;328(5):430-439. doi: 10.1001/jama.2022.9930. PMID: 35916848Free PMC Article
It's never too late - balance and endurance training improves functional performance, quality of life, and alleviates neuropathic symptoms in cancer survivors suffering from chemotherapy-induced peripheral neuropathy: results of a randomized controlled trial.
Kneis S, Wehrle A, Müller J, Maurer C, Ihorst G, Gollhofer A, Bertz H
BMC Cancer 2019 May 2;19(1):414. doi: 10.1186/s12885-019-5522-7. PMID: 31046719Free PMC Article
Preventing foot ulcers in patients with diabetes.
Singh N, Armstrong DG, Lipsky BA
JAMA 2005 Jan 12;293(2):217-28. doi: 10.1001/jama.293.2.217. PMID: 15644549
Genioplasty.
Stanton DC
Facial Plast Surg 2003 Feb;19(1):75-86. doi: 10.1055/s-2003-39130. PMID: 12739183

Prognosis

Assessment of Somatosensory Function and Self-harm in Adolescents.
Cummins TM, English O, Minnis H, Stahl D, O'Connor RC, Bannister K, McMahon SB, Ougrin D
JAMA Netw Open 2021 Jul 1;4(7):e2116853. doi: 10.1001/jamanetworkopen.2021.16853. PMID: 34255048Free PMC Article
Isolated Insular Stroke: Clinical Presentation.
Giammello F, Cosenza D, Casella C, Granata F, Dell'Aera C, Fazio MC, La Spina P, Grillo F, Cotroneo M, Toscano A, Musolino RF
Cerebrovasc Dis 2020;49(1):10-18. Epub 2020 Feb 5 doi: 10.1159/000504777. PMID: 32023607
How do somatosensory deficits in the arm and hand relate to upper limb impairment, activity, and participation problems after stroke? A systematic review.
Meyer S, Karttunen AH, Thijs V, Feys H, Verheyden G
Phys Ther 2014 Sep;94(9):1220-31. Epub 2014 Apr 24 doi: 10.2522/ptj.20130271. PMID: 24764072
On the nature of nondermatomal somatosensory deficits.
Mailis-Gagnon A, Nicholson K
Clin J Pain 2011 Jan;27(1):76-84. doi: 10.1097/AJP.0b013e3181e8d9cc. PMID: 20664332
Interpreting joint pain: quantitative sensory testing in musculoskeletal management.
Courtney CA, Kavchak AE, Lowry CD, O'Hearn MA
J Orthop Sports Phys Ther 2010 Dec;40(12):818-25. Epub 2010 Oct 22 doi: 10.2519/jospt.2010.3314. PMID: 20972347

Clinical prediction guides

Somatosensory Impairment and Chronic Pain Following Stroke: An Observational Study.
Haslam BS, Butler DS, Kim AS, Carey LM
Int J Environ Res Public Health 2023 Jan 4;20(2) doi: 10.3390/ijerph20020906. PMID: 36673661Free PMC Article
Assessment of Somatosensory Function and Self-harm in Adolescents.
Cummins TM, English O, Minnis H, Stahl D, O'Connor RC, Bannister K, McMahon SB, Ougrin D
JAMA Netw Open 2021 Jul 1;4(7):e2116853. doi: 10.1001/jamanetworkopen.2021.16853. PMID: 34255048Free PMC Article
Nociplastic pain: towards an understanding of prevalent pain conditions.
Fitzcharles MA, Cohen SP, Clauw DJ, Littlejohn G, Usui C, Häuser W
Lancet 2021 May 29;397(10289):2098-2110. doi: 10.1016/S0140-6736(21)00392-5. PMID: 34062144
It's never too late - balance and endurance training improves functional performance, quality of life, and alleviates neuropathic symptoms in cancer survivors suffering from chemotherapy-induced peripheral neuropathy: results of a randomized controlled trial.
Kneis S, Wehrle A, Müller J, Maurer C, Ihorst G, Gollhofer A, Bertz H
BMC Cancer 2019 May 2;19(1):414. doi: 10.1186/s12885-019-5522-7. PMID: 31046719Free PMC Article
Sensory processing in children with and without autism: a comparative study using the short sensory profile.
Tomchek SD, Dunn W
Am J Occup Ther 2007 Mar-Apr;61(2):190-200. doi: 10.5014/ajot.61.2.190. PMID: 17436841

Recent systematic reviews

Interventions for perceptual disorders following stroke.
Hazelton C, Thomson K, Todhunter-Brown A, Campbell P, Chung CS, Dorris L, Gillespie DC, Hunter SM, McGill K, Nicolson DJ, Williams LJ, Brady MC
Cochrane Database Syst Rev 2022 Nov 3;11(11):CD007039. doi: 10.1002/14651858.CD007039.pub3. PMID: 36326118Free PMC Article
Systematic Review and Meta-Analysis of Management Strategies and Outcomes in Adult Spinal Neurocysticercosis.
Barrie U, Badejo O, Aoun SG, Adeyemo E, Moler N, Christian ZK, Caruso JP, El Ahmadieh TY, Ban VS, MacAllister MC, Reyes VP, Hall K, Whitworth L, Bagley CA
World Neurosurg 2020 Jun;138:504-511.e8. Epub 2020 Mar 27 doi: 10.1016/j.wneu.2020.03.093. PMID: 32224269
Prevalence, incidence, and risk factors for shoulder and neck dysfunction after neck dissection: A systematic review.
Gane EM, Michaleff ZA, Cottrell MA, McPhail SM, Hatton AL, Panizza BJ, O'Leary SP
Eur J Surg Oncol 2017 Jul;43(7):1199-1218. Epub 2016 Nov 17 doi: 10.1016/j.ejso.2016.10.026. PMID: 27956321
Corticosteroids for treating nerve damage in leprosy.
Van Veen NH, Nicholls PG, Smith WC, Richardus JH
Cochrane Database Syst Rev 2016 May 23;2016(5):CD005491. doi: 10.1002/14651858.CD005491.pub3. PMID: 27210895Free PMC Article
How do somatosensory deficits in the arm and hand relate to upper limb impairment, activity, and participation problems after stroke? A systematic review.
Meyer S, Karttunen AH, Thijs V, Feys H, Verheyden G
Phys Ther 2014 Sep;94(9):1220-31. Epub 2014 Apr 24 doi: 10.2522/ptj.20130271. PMID: 24764072

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