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Cardiac Valvular Regurgitation Likely Etiology

MedGen UID:
1612451
•Concept ID:
C4528249
•
Finding

Definition

An estimation as to the cause of the pathology responsible for the cardiac valve regurgitation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac Valvular Regurgitation Likely Etiology

Professional guidelines

PubMed

Variation in the Echocardiographic Surveillance of Primary Mitral Regurgitation.
Tanguturi VK, Hidrue MK, Picard MH, Atlas SJ, Weilburg JB, Ferris TG, Armstrong K, Wasfy JH
Circ Cardiovasc Imaging 2017 Aug;10(8) doi: 10.1161/CIRCIMAGING.117.006495. PMID: 28774932Free PMC Article

Recent clinical studies

Etiology

Combined Significant Aortic Stenosis and Mitral Regurgitation: Challenges in Timing and Type of Intervention.
Alaour B, Nakase M, Pilgrim T
Can J Cardiol 2024 Feb;40(2):235-249. Epub 2023 Nov 4 doi: 10.1016/j.cjca.2023.11.003. PMID: 37931671
Arrhythmia and impaired myocardial function in heritable thoracic aortic disease: An international retrospective cohort study.
Demolder A, Bianco L, Caruana M, Cervi E, Evangelista A, Jondeau G, Buttigieg LL, López-Sainz Á, Delmás EM, Pini A, Sabaté-Rotés A, Szöcs K, Tchitchinadze M, Teixidó-Tura G, von Kodolitsch Y, Muiño-Mosquera L, De Backer J
Eur J Med Genet 2022 Jun;65(6):104503. Epub 2022 Apr 12 doi: 10.1016/j.ejmg.2022.104503. PMID: 35427808
Association between pregnancy and long-term cardiac outcomes in individuals with congenital heart disease.
Son SL, Hosek LL, Stein MC, Allshouse AA, Catino AB, Hoskoppal AK, Cox DA, Whitehead KJ, Lindsay IM, Esplin S, Metz TD
Am J Obstet Gynecol 2022 Jan;226(1):124.e1-124.e8. Epub 2021 Jul 28 doi: 10.1016/j.ajog.2021.07.015. PMID: 34331895Free PMC Article
Cardiovascular and Obstetric Delivery Complications in Pregnant Women With Valvular Heart Disease.
Minhas AS, Rahman F, Gavin N, Cedars A, Vaught AJ, Zakaria S, Resar J, Schena S, Schulman S, Zhao D, Hays AG, Michos ED
Am J Cardiol 2021 Nov 1;158:90-97. Epub 2021 Aug 24 doi: 10.1016/j.amjcard.2021.07.038. PMID: 34452683Free PMC Article
Cabergoline therapy and the risk of cardiac valve regurgitation in patients with hyperprolactinemia: a meta-analysis from clinical studies.
Bogazzi F, Manetti L, Raffaelli V, Lombardi M, Rossi G, Martino E
J Endocrinol Invest 2008 Dec;31(12):1119-23. doi: 10.1007/BF03345662. PMID: 19246980

Diagnosis

Combined Significant Aortic Stenosis and Mitral Regurgitation: Challenges in Timing and Type of Intervention.
Alaour B, Nakase M, Pilgrim T
Can J Cardiol 2024 Feb;40(2):235-249. Epub 2023 Nov 4 doi: 10.1016/j.cjca.2023.11.003. PMID: 37931671
Association between pregnancy and long-term cardiac outcomes in individuals with congenital heart disease.
Son SL, Hosek LL, Stein MC, Allshouse AA, Catino AB, Hoskoppal AK, Cox DA, Whitehead KJ, Lindsay IM, Esplin S, Metz TD
Am J Obstet Gynecol 2022 Jan;226(1):124.e1-124.e8. Epub 2021 Jul 28 doi: 10.1016/j.ajog.2021.07.015. PMID: 34331895Free PMC Article
Readmission Risk Factors and Heart Failure With Preserved Ejection Fraction.
Harmon D, Rathousky J, Choudhry F, Grover H, Patel I, Jacobson T, Boura J, Crawford J, Arnautovic J
J Am Osteopath Assoc 2020 Dec 1;120(12):831-838. doi: 10.7556/jaoa.2020.154. PMID: 33125031
A meta-analysis of reduced leaflet motion for surgical and transcatheter aortic valves: Relationship to cerebrovascular events and valve degeneration.
Makki N, Shreenivas S, Kereiakes D, Lilly S
Cardiovasc Revasc Med 2018 Oct-Nov;19(7 Pt B):868-873. Epub 2018 Apr 5 doi: 10.1016/j.carrev.2018.03.003. PMID: 29759854
Bicuspid aortic valve.
Yener N, Oktar GL, Erer D, Yardimci MM, Yener A
Ann Thorac Cardiovasc Surg 2002 Oct;8(5):264-7. PMID: 12472407

Therapy

ISCHEMIC MITRAL REGURGITATION - TO REPAIR OR REPLACE? LOOKING BEYOND THE VALVE.
Mil-Homens Luz F, Amorim MJ
Port J Card Thorac Vasc Surg 2022 Apr 11;29(1):25-34. doi: 10.48729/pjctvs.253. PMID: 35471215
Readmission Risk Factors and Heart Failure With Preserved Ejection Fraction.
Harmon D, Rathousky J, Choudhry F, Grover H, Patel I, Jacobson T, Boura J, Crawford J, Arnautovic J
J Am Osteopath Assoc 2020 Dec 1;120(12):831-838. doi: 10.7556/jaoa.2020.154. PMID: 33125031
Cabergoline therapy and the risk of cardiac valve regurgitation in patients with hyperprolactinemia: a meta-analysis from clinical studies.
Bogazzi F, Manetti L, Raffaelli V, Lombardi M, Rossi G, Martino E
J Endocrinol Invest 2008 Dec;31(12):1119-23. doi: 10.1007/BF03345662. PMID: 19246980
Tricuspid valve replacement after cardiac transplantation.
Badiwala MV, Rao V
Curr Opin Cardiol 2007 Mar;22(2):123-7. doi: 10.1097/HCO.0b013e3280125472. PMID: 17284991
Morphologic features of the normal and abnormal mitral valve.
Roberts WC
Am J Cardiol 1983 Mar 15;51(6):1005-28. doi: 10.1016/s0002-9149(83)80181-7. PMID: 6338691

Prognosis

Combined Significant Aortic Stenosis and Mitral Regurgitation: Challenges in Timing and Type of Intervention.
Alaour B, Nakase M, Pilgrim T
Can J Cardiol 2024 Feb;40(2):235-249. Epub 2023 Nov 4 doi: 10.1016/j.cjca.2023.11.003. PMID: 37931671
Association between pregnancy and long-term cardiac outcomes in individuals with congenital heart disease.
Son SL, Hosek LL, Stein MC, Allshouse AA, Catino AB, Hoskoppal AK, Cox DA, Whitehead KJ, Lindsay IM, Esplin S, Metz TD
Am J Obstet Gynecol 2022 Jan;226(1):124.e1-124.e8. Epub 2021 Jul 28 doi: 10.1016/j.ajog.2021.07.015. PMID: 34331895Free PMC Article
Top End Pulmonary Hypertension Study: Understanding Epidemiology, Therapeutic Gaps and Prognosis in Remote Australian Setting.
Naing P, Playford D, Strange G, Abeyaratne A, Berhane T, Joseph S, Costelloe E, Hall M, Scalia GM, Forrester DL, Falhammar H, Kangaharan N
Heart Lung Circ 2021 Apr;30(4):507-515. Epub 2020 Sep 19 doi: 10.1016/j.hlc.2020.08.008. PMID: 32962944
Readmission Risk Factors and Heart Failure With Preserved Ejection Fraction.
Harmon D, Rathousky J, Choudhry F, Grover H, Patel I, Jacobson T, Boura J, Crawford J, Arnautovic J
J Am Osteopath Assoc 2020 Dec 1;120(12):831-838. doi: 10.7556/jaoa.2020.154. PMID: 33125031
Tricuspid valve replacement after cardiac transplantation.
Badiwala MV, Rao V
Curr Opin Cardiol 2007 Mar;22(2):123-7. doi: 10.1097/HCO.0b013e3280125472. PMID: 17284991

Clinical prediction guides

Impact of mitral regurgitation in patients with acute heart failure: insights from the RELAX-AHF-2 trial.
Pagnesi M, Adamo M, Ter Maaten JM, Beldhuis IE, Cotter G, Davison BA, Felker GM, Filippatos G, Greenberg BH, Pang PS, Ponikowski P, Sama IE, Severin T, Gimpelewicz C, Voors AA, Teerlink JR, Metra M
Eur J Heart Fail 2023 Apr;25(4):541-552. Epub 2023 Mar 13 doi: 10.1002/ejhf.2820. PMID: 36915227
Association between pregnancy and long-term cardiac outcomes in individuals with congenital heart disease.
Son SL, Hosek LL, Stein MC, Allshouse AA, Catino AB, Hoskoppal AK, Cox DA, Whitehead KJ, Lindsay IM, Esplin S, Metz TD
Am J Obstet Gynecol 2022 Jan;226(1):124.e1-124.e8. Epub 2021 Jul 28 doi: 10.1016/j.ajog.2021.07.015. PMID: 34331895Free PMC Article
Readmission Risk Factors and Heart Failure With Preserved Ejection Fraction.
Harmon D, Rathousky J, Choudhry F, Grover H, Patel I, Jacobson T, Boura J, Crawford J, Arnautovic J
J Am Osteopath Assoc 2020 Dec 1;120(12):831-838. doi: 10.7556/jaoa.2020.154. PMID: 33125031
A meta-analysis of reduced leaflet motion for surgical and transcatheter aortic valves: Relationship to cerebrovascular events and valve degeneration.
Makki N, Shreenivas S, Kereiakes D, Lilly S
Cardiovasc Revasc Med 2018 Oct-Nov;19(7 Pt B):868-873. Epub 2018 Apr 5 doi: 10.1016/j.carrev.2018.03.003. PMID: 29759854
Tricuspid valve replacement after cardiac transplantation.
Badiwala MV, Rao V
Curr Opin Cardiol 2007 Mar;22(2):123-7. doi: 10.1097/HCO.0b013e3280125472. PMID: 17284991

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