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Calculated Right Ventricular Ejection Fraction

MedGen UID:
1624743
•Concept ID:
C4525756
•
Finding

Definition

The percent or fraction of the right ventricular end diastolic volume ejected in systole, which is calculated as the right ventricular stroke volume divided by the right ventricular end diastolic volume. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCalculated Right Ventricular Ejection Fraction

Professional guidelines

PubMed

Pacing-induced cardiomyopathy: A systematic review and meta-analysis of definition, prevalence, risk factors, and management.
Somma V, Ha FJ, Palmer S, Mohamed U, Agarwal S
Heart Rhythm 2023 Feb;20(2):282-290. Epub 2022 Nov 7 doi: 10.1016/j.hrthm.2022.09.019. PMID: 36356656
Clinical study on the treatment of chronic heart failure with a novel D-shant atrium shunt device.
Shang X, Liu M, Zhong Y, Wang X, Chen S, Fu X, Sun M, Xie M, Ke Y, Guan Y, Zhang C, Dong N
ESC Heart Fail 2022 Jun;9(3):1713-1720. Epub 2022 Feb 18 doi: 10.1002/ehf2.13842. PMID: 35179320Free PMC Article
Clinical utility of right ventricular fractional area change in preterm infants.
James AT, Corcoran JD, Franklin O, El-Khuffash AF
Early Hum Dev 2016 Jan;92:19-23. Epub 2015 Nov 24 doi: 10.1016/j.earlhumdev.2015.10.015. PMID: 26619069

Recent clinical studies

Etiology

Pacing-induced cardiomyopathy: A systematic review and meta-analysis of definition, prevalence, risk factors, and management.
Somma V, Ha FJ, Palmer S, Mohamed U, Agarwal S
Heart Rhythm 2023 Feb;20(2):282-290. Epub 2022 Nov 7 doi: 10.1016/j.hrthm.2022.09.019. PMID: 36356656
Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis.
Wilkinson-Stokes M, Betson J, Sawyer S
Emerg Med J 2023 Feb;40(2):108-113. Epub 2022 Sep 30 doi: 10.1136/emermed-2021-212294. PMID: 36180168
Right Ventricular-Pulmonary Arterial Coupling and Afterload Reserve in Patients Undergoing Transcatheter Tricuspid Valve Repair.
Brener MI, Lurz P, Hausleiter J, Rodés-Cabau J, Fam N, Kodali SK, Rommel KP, Muntané-Carol G, Gavazzoni M, Nazif TM, Pozzoli A, Alessandrini H, Latib A, Biasco L, Braun D, Brochet E, Denti P, Lubos E, Ludwig S, Kalbacher D, Estevez-Loureiro R, Connelly KA, Frerker C, Ho EC, Juliard JM, Harr C, Monivas V, Nickenig G, Pedrazzini G, Philippon F, Praz F, Puri R, Schofer J, Sievert H, Tang GHL, Andreas M, Thiele H, Unterhuber M, Himbert D, Alcázar MU, Von Bardeleben RS, Windecker S, Wild MG, Maisano F, Leon MB, Taramasso M, Hahn RT
J Am Coll Cardiol 2022 Feb 8;79(5):448-461. doi: 10.1016/j.jacc.2021.11.031. PMID: 35115101
Right Ventricular Volumes, Ejection Fraction, and Systolic Function Indices in Normal Neonates by Three-Dimensional Speckle-Tracking Echocardiography.
Bulbul Z, Siblini G, Tamim H, Makki M, Bitar F
Pediatr Cardiol 2022 Jan;43(1):181-190. Epub 2021 Sep 1 doi: 10.1007/s00246-021-02716-9. PMID: 34468773
Reversing the Cardiac Effects of Sedentary Aging in Middle Age-A Randomized Controlled Trial: Implications For Heart Failure Prevention.
Howden EJ, Sarma S, Lawley JS, Opondo M, Cornwell W, Stoller D, Urey MA, Adams-Huet B, Levine BD
Circulation 2018 Apr 10;137(15):1549-1560. Epub 2018 Jan 8 doi: 10.1161/CIRCULATIONAHA.117.030617. PMID: 29311053Free PMC Article

Diagnosis

Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis.
Wilkinson-Stokes M, Betson J, Sawyer S
Emerg Med J 2023 Feb;40(2):108-113. Epub 2022 Sep 30 doi: 10.1136/emermed-2021-212294. PMID: 36180168
Prevalence and Disease Expression of Pathogenic and Likely Pathogenic Variants Associated With Inherited Cardiomyopathies in the General Population.
Bourfiss M, van Vugt M, Alasiri AI, Ruijsink B, van Setten J, Schmidt AF, Dooijes D, Puyol-Antón E, Velthuis BK, van Tintelen JP, Te Riele ASJM, Baas AF, Asselbergs FW
Circ Genom Precis Med 2022 Dec;15(6):e003704. Epub 2022 Oct 20 doi: 10.1161/CIRCGEN.122.003704. PMID: 36264615Free PMC Article
Diffuse right ventricular fibrosis in heart failure with preserved ejection fraction and pulmonary hypertension.
Patel RB, Li E, Benefield BC, Swat SA, Polsinelli VB, Carr JC, Shah SJ, Markl M, Collins JD, Freed BH
ESC Heart Fail 2020 Feb;7(1):253-263. Epub 2020 Jan 5 doi: 10.1002/ehf2.12565. PMID: 31903694Free PMC Article
Reversing the Cardiac Effects of Sedentary Aging in Middle Age-A Randomized Controlled Trial: Implications For Heart Failure Prevention.
Howden EJ, Sarma S, Lawley JS, Opondo M, Cornwell W, Stoller D, Urey MA, Adams-Huet B, Levine BD
Circulation 2018 Apr 10;137(15):1549-1560. Epub 2018 Jan 8 doi: 10.1161/CIRCULATIONAHA.117.030617. PMID: 29311053Free PMC Article
Pulsus paradoxus.
Hamzaoui O, Monnet X, Teboul JL
Eur Respir J 2013 Dec;42(6):1696-705. Epub 2012 Dec 6 doi: 10.1183/09031936.00138912. PMID: 23222878

Therapy

Prognostic value of the right ventricular ejection fraction using three-dimensional echocardiography: Systematic review and meta-analysis.
Kitano T, Nabeshima Y, Nagata Y, Takeuchi M
PLoS One 2023;18(7):e0287924. Epub 2023 Jul 7 doi: 10.1371/journal.pone.0287924. PMID: 37418388Free PMC Article
Pacing-induced cardiomyopathy: A systematic review and meta-analysis of definition, prevalence, risk factors, and management.
Somma V, Ha FJ, Palmer S, Mohamed U, Agarwal S
Heart Rhythm 2023 Feb;20(2):282-290. Epub 2022 Nov 7 doi: 10.1016/j.hrthm.2022.09.019. PMID: 36356656
Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis.
Wilkinson-Stokes M, Betson J, Sawyer S
Emerg Med J 2023 Feb;40(2):108-113. Epub 2022 Sep 30 doi: 10.1136/emermed-2021-212294. PMID: 36180168
Pulmonary artery wave reflection and right ventricular function after lung resection.
Glass A, McCall P, Arthur A, Mangion K, Shelley B
Br J Anaesth 2023 Jan;130(1):e128-e136. Epub 2022 Sep 15 doi: 10.1016/j.bja.2022.07.052. PMID: 36115714Free PMC Article
Reversing the Cardiac Effects of Sedentary Aging in Middle Age-A Randomized Controlled Trial: Implications For Heart Failure Prevention.
Howden EJ, Sarma S, Lawley JS, Opondo M, Cornwell W, Stoller D, Urey MA, Adams-Huet B, Levine BD
Circulation 2018 Apr 10;137(15):1549-1560. Epub 2018 Jan 8 doi: 10.1161/CIRCULATIONAHA.117.030617. PMID: 29311053Free PMC Article

Prognosis

Left ventricular dysfunction and intra-ventricular dyssynchrony in idiopathic pulmonary arterial hypertension.
Jayasekera G, Macdonald A, Mccomb C, Orchard V, Welsh D, Church C, Johnson M, Brewis M, Berry C, Radjenovic A, Peacock A
Int J Cardiol 2022 Oct 15;365:131-139. Epub 2022 Jul 21 doi: 10.1016/j.ijcard.2022.07.032. PMID: 35870633
Right Ventricular-Pulmonary Arterial Coupling and Afterload Reserve in Patients Undergoing Transcatheter Tricuspid Valve Repair.
Brener MI, Lurz P, Hausleiter J, Rodés-Cabau J, Fam N, Kodali SK, Rommel KP, Muntané-Carol G, Gavazzoni M, Nazif TM, Pozzoli A, Alessandrini H, Latib A, Biasco L, Braun D, Brochet E, Denti P, Lubos E, Ludwig S, Kalbacher D, Estevez-Loureiro R, Connelly KA, Frerker C, Ho EC, Juliard JM, Harr C, Monivas V, Nickenig G, Pedrazzini G, Philippon F, Praz F, Puri R, Schofer J, Sievert H, Tang GHL, Andreas M, Thiele H, Unterhuber M, Himbert D, Alcázar MU, Von Bardeleben RS, Windecker S, Wild MG, Maisano F, Leon MB, Taramasso M, Hahn RT
J Am Coll Cardiol 2022 Feb 8;79(5):448-461. doi: 10.1016/j.jacc.2021.11.031. PMID: 35115101
Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts.
Weaver NA, Kuijf HJ, Aben HP, Abrigo J, Bae HJ, Barbay M, Best JG, Bordet R, Chappell FM, Chen CPLH, Dondaine T, van der Giessen RS, Godefroy O, Gyanwali B, Hamilton OKL, Hilal S, Huenges Wajer IMC, Kang Y, Kappelle LJ, Kim BJ, Köhler S, de Kort PLM, Koudstaal PJ, Kuchcinski G, Lam BYK, Lee BC, Lee KJ, Lim JS, Lopes R, Makin SDJ, Mendyk AM, Mok VCT, Oh MS, van Oostenbrugge RJ, Roussel M, Shi L, Staals J, Del C Valdés-Hernández M, Venketasubramanian N, Verhey FRJ, Wardlaw JM, Werring DJ, Xin X, Yu KH, van Zandvoort MJE, Zhao L, Biesbroek JM, Biessels GJ
Lancet Neurol 2021 Jun;20(6):448-459. Epub 2021 Apr 23 doi: 10.1016/S1474-4422(21)00060-0. PMID: 33901427
Diffuse right ventricular fibrosis in heart failure with preserved ejection fraction and pulmonary hypertension.
Patel RB, Li E, Benefield BC, Swat SA, Polsinelli VB, Carr JC, Shah SJ, Markl M, Collins JD, Freed BH
ESC Heart Fail 2020 Feb;7(1):253-263. Epub 2020 Jan 5 doi: 10.1002/ehf2.12565. PMID: 31903694Free PMC Article
Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta-analysis.
Gorter TM, Hoendermis ES, van Veldhuisen DJ, Voors AA, Lam CS, Geelhoed B, Willems TP, van Melle JP
Eur J Heart Fail 2016 Dec;18(12):1472-1487. Epub 2016 Sep 20 doi: 10.1002/ejhf.630. PMID: 27650220

Clinical prediction guides

Programmed Ventricular Stimulation as an Additional Primary Prevention Risk Stratification Tool in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Study.
Gasperetti A, Carrick RT, Costa S, Compagnucci P, Bosman LP, Chivulescu M, Tichnell C, Murray B, Tandri H, Tadros R, Rivard L, van den Berg MP, Zeppenfeld K, Wilde AAM, Pompilio G, Carbucicchio C, Dello Russo A, Casella M, Svensson A, Brunckhorst CB, van Tintelen JP, Platonov PG, Haugaa KH, Duru F, Te Riele ASJM, Khairy P, Tondo C, Calkins H, James CA, Saguner AM, Cadrin-Tourigny J
Circulation 2022 Nov 8;146(19):1434-1443. Epub 2022 Oct 7 doi: 10.1161/CIRCULATIONAHA.122.060866. PMID: 36205131Free PMC Article
Left ventricular dysfunction and intra-ventricular dyssynchrony in idiopathic pulmonary arterial hypertension.
Jayasekera G, Macdonald A, Mccomb C, Orchard V, Welsh D, Church C, Johnson M, Brewis M, Berry C, Radjenovic A, Peacock A
Int J Cardiol 2022 Oct 15;365:131-139. Epub 2022 Jul 21 doi: 10.1016/j.ijcard.2022.07.032. PMID: 35870633
Right Ventricular-Pulmonary Arterial Coupling and Afterload Reserve in Patients Undergoing Transcatheter Tricuspid Valve Repair.
Brener MI, Lurz P, Hausleiter J, Rodés-Cabau J, Fam N, Kodali SK, Rommel KP, Muntané-Carol G, Gavazzoni M, Nazif TM, Pozzoli A, Alessandrini H, Latib A, Biasco L, Braun D, Brochet E, Denti P, Lubos E, Ludwig S, Kalbacher D, Estevez-Loureiro R, Connelly KA, Frerker C, Ho EC, Juliard JM, Harr C, Monivas V, Nickenig G, Pedrazzini G, Philippon F, Praz F, Puri R, Schofer J, Sievert H, Tang GHL, Andreas M, Thiele H, Unterhuber M, Himbert D, Alcázar MU, Von Bardeleben RS, Windecker S, Wild MG, Maisano F, Leon MB, Taramasso M, Hahn RT
J Am Coll Cardiol 2022 Feb 8;79(5):448-461. doi: 10.1016/j.jacc.2021.11.031. PMID: 35115101
Pulsus paradoxus.
Hamzaoui O, Monnet X, Teboul JL
Eur Respir J 2013 Dec;42(6):1696-705. Epub 2012 Dec 6 doi: 10.1183/09031936.00138912. PMID: 23222878
Right ventricular tissue Doppler and strain imaging: ready for clinical use?
Gondi S, Dokainish H
Echocardiography 2007 May;24(5):522-32. doi: 10.1111/j.1540-8175.2007.00430.x. PMID: 17456072

Recent systematic reviews

Long-term outcome of patients with transposition of the great arteries and a systemic right ventricle: A systematic review and meta-analysis.
Ansari Ramandi MM, Yarmohammadi H, Gareb B, Voors AA, van Melle JP
Int J Cardiol 2023 Oct 15;389:131159. Epub 2023 Jul 9 doi: 10.1016/j.ijcard.2023.131159. PMID: 37433408
Prognostic value of the right ventricular ejection fraction using three-dimensional echocardiography: Systematic review and meta-analysis.
Kitano T, Nabeshima Y, Nagata Y, Takeuchi M
PLoS One 2023;18(7):e0287924. Epub 2023 Jul 7 doi: 10.1371/journal.pone.0287924. PMID: 37418388Free PMC Article
Pacing-induced cardiomyopathy: A systematic review and meta-analysis of definition, prevalence, risk factors, and management.
Somma V, Ha FJ, Palmer S, Mohamed U, Agarwal S
Heart Rhythm 2023 Feb;20(2):282-290. Epub 2022 Nov 7 doi: 10.1016/j.hrthm.2022.09.019. PMID: 36356656
Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis.
Wilkinson-Stokes M, Betson J, Sawyer S
Emerg Med J 2023 Feb;40(2):108-113. Epub 2022 Sep 30 doi: 10.1136/emermed-2021-212294. PMID: 36180168
Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta-analysis.
Gorter TM, Hoendermis ES, van Veldhuisen DJ, Voors AA, Lam CS, Geelhoed B, Willems TP, van Melle JP
Eur J Heart Fail 2016 Dec;18(12):1472-1487. Epub 2016 Sep 20 doi: 10.1002/ejhf.630. PMID: 27650220

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