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Abnormal cytokine signaling

MedGen UID:
1627114
Concept ID:
C4531145
Cell or Molecular Dysfunction
Synonym: Abnormal cytokine signalling
 
HPO: HP:0031406

Definition

Any abnormality in the series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal cytokine signaling

Professional guidelines

PubMed

Lé AM, Puig L, Torres T
Am J Clin Dermatol 2022 Nov;23(6):813-822. Epub 2022 Aug 12 doi: 10.1007/s40257-022-00720-0. PMID: 35960487Free PMC Article
Shen S, Liao Q, Wong YK, Chen X, Yang C, Xu C, Sun J, Wang J
Int J Biol Sci 2022;18(3):983-994. Epub 2022 Jan 1 doi: 10.7150/ijbs.66871. PMID: 35173531Free PMC Article
Thenappan T, Ormiston ML, Ryan JJ, Archer SL
BMJ 2018 Mar 14;360:j5492. doi: 10.1136/bmj.j5492. PMID: 29540357Free PMC Article

Recent clinical studies

Clinical prediction guides

Person T, King RG, Rizk DV, Novak J, Green TJ, Reily C
J Interferon Cytokine Res 2022 Jul;42(7):301-315. Epub 2022 Jul 6 doi: 10.1089/jir.2022.0039. PMID: 35793525Free PMC Article

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