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Meconium xenobiotic

MedGen UID:
1634799
•Concept ID:
C4703717
•
Finding
HPO: HP:0500098

Definition

Presence of a xenobiotic in meconium. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMeconium xenobiotic

Recent clinical studies

Etiology

The atlas of dialkylphosphates; assessment of cumulative human organophosphorus pesticides' exposure.
Kavvalakis MP, Tsatsakis AM
Forensic Sci Int 2012 May 10;218(1-3):111-22. Epub 2011 Oct 21 doi: 10.1016/j.forsciint.2011.10.019. PMID: 22018851
Maternal-infant biomonitoring of environmental chemicals: the epidemiologic challenges.
Arbuckle TE
Birth Defects Res A Clin Mol Teratol 2010 Oct;88(10):931-7. doi: 10.1002/bdra.20694. PMID: 20706992
Dialkyl phosphates in meconium as a biomarker of prenatal exposure to organophosphate pesticides: a study on pregnant women of rural areas in Crete, Greece.
Tsatsakis AM, Tzatzarakis MN, Koutroulakis D, Toutoudaki M, Sifakis S
Xenobiotica 2009 May;39(5):364-73. doi: 10.1080/00498250902745090. PMID: 19387892

Diagnosis

Alternative matrices in forensic toxicology: a critical review.
de Campos EG, da Costa BRB, Dos Santos FS, Monedeiro F, Alves MNR, Santos Junior WJR, De Martinis BS
Forensic Toxicol 2022 Jan;40(1):1-18. Epub 2021 Aug 19 doi: 10.1007/s11419-021-00596-5. PMID: 36454488Free PMC Article
Development of a multi-residue method in a fetal matrix: analysis of meconium.
Meyer-Monath M, Chatellier C, Rouget F, Morel I, Lestremau F
Anal Bioanal Chem 2014 Dec;406(30):7785-97. Epub 2014 Nov 9 doi: 10.1007/s00216-014-8243-4. PMID: 25381610
Analysis of BTEX and chlorinated solvents in meconium by headspace-solid-phase microextraction gas chromatography coupled with mass spectrometry.
Meyer-Monath M, Beaumont J, Morel I, Rouget F, Tack K, Lestremau F
Anal Bioanal Chem 2014 Jul;406(18):4481-90. Epub 2014 May 18 doi: 10.1007/s00216-014-7836-2. PMID: 24838489
Emerging biomarkers of intrauterine neonatal and pediatric exposures to xenobiotics.
Delano K, Koren G
Pediatr Clin North Am 2012 Oct;59(5):1059-70. Epub 2012 Aug 22 doi: 10.1016/j.pcl.2012.07.005. PMID: 23036244
Estimation of fetal exposure to drugs of abuse, environmental tobacco smoke, and ethanol.
Koren G, Chan D, Klein J, Karaskov T
Ther Drug Monit 2002 Feb;24(1):23-5. doi: 10.1097/00007691-200202000-00004. PMID: 11805717

Therapy

Spectrum of gestational exposure to illicit drugs and other xenobiotic agents in newborn infants by meconium analysis.
Ostrea EM Jr, Matias O, Keane C, Mac E, Utarnachitt R, Ostrea A, Mazhar M
J Pediatr 1998 Oct;133(4):513-5. doi: 10.1016/s0022-3476(98)70059-9. PMID: 9787689

Prognosis

Fetal cardiac growth is associated with in utero gut colonization.
Guzzardi MA, Ait Ali L, D'Aurizio R, Rizzo F, Saggese P, Sanguinetti E, Weisz A, Pellegrini M, Iozzo P
Nutr Metab Cardiovasc Dis 2019 Feb;29(2):170-176. Epub 2018 Oct 19 doi: 10.1016/j.numecd.2018.10.005. PMID: 30579777

Clinical prediction guides

Pesticides analysis in alternative biological matrices.
Crocoli LC, Menck RA, Moura S
Drug Chem Toxicol 2023 Nov;46(4):809-824. Epub 2022 Jun 23 doi: 10.1080/01480545.2022.2090574. PMID: 35734890
Fetal cardiac growth is associated with in utero gut colonization.
Guzzardi MA, Ait Ali L, D'Aurizio R, Rizzo F, Saggese P, Sanguinetti E, Weisz A, Pellegrini M, Iozzo P
Nutr Metab Cardiovasc Dis 2019 Feb;29(2):170-176. Epub 2018 Oct 19 doi: 10.1016/j.numecd.2018.10.005. PMID: 30579777
Hair analysis of opiates in mothers and newborns for evaluating opiate exposure during pregnancy.
Vinner E, Vignau J, Thibault D, Codaccioni X, Brassart C, Humbert L, Lhermitte M
Forensic Sci Int 2003 Apr 23;133(1-2):57-62. doi: 10.1016/s0379-0738(03)00050-1. PMID: 12742690

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