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Mean Pressure Gradient

MedGen UID:
1637244
•Concept ID:
C4687744
•
Finding

Definition

The arithmetic average of the quantitative measurement of the pressure gradient across a predetermined point. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMean Pressure Gradient

Professional guidelines

PubMed

Treatment of severe symptomatic aortic valve stenosis using non-invasive ultrasound therapy: a cohort study.
Messas E, Ijsselmuiden A, Trifunović-Zamaklar D, Cholley B, Puymirat E, Halim J, Karan R, van Gameren M, Terzić D, Milićević V, Tanter M, Pernot M, Goudot G
Lancet 2023 Dec 16;402(10419):2317-2325. Epub 2023 Nov 14 doi: 10.1016/S0140-6736(23)01518-0. PMID: 37972628
The current diagnosis and treatment of patients with aortic valve stenosis.
Henning RJ
Future Cardiol 2021 Sep;17(6):1143-1160. Epub 2021 Mar 17 doi: 10.2217/fca-2020-0140. PMID: 33728942
Progression of aortic stenosis and echocardiographic criteria for its severity.
Kebed K, Sun D, Addetia K, Mor-Avi V, Markuzon N, Lang RM
Eur Heart J Cardiovasc Imaging 2020 Jul 1;21(7):737-743. doi: 10.1093/ehjci/jeaa075. PMID: 32335667Free PMC Article

Recent clinical studies

Etiology

Prevalence and Outcomes of Patients With Discordant High-Gradient Aortic Stenosis.
Unger P, Powers A, Le Nezet E, Lacasse-Rioux E, Galloo X, Clavel MA
J Am Coll Cardiol 2024 Mar 26;83(12):1109-1119. doi: 10.1016/j.jacc.2024.01.025. PMID: 38508842
Treatment of severe symptomatic aortic valve stenosis using non-invasive ultrasound therapy: a cohort study.
Messas E, Ijsselmuiden A, Trifunović-Zamaklar D, Cholley B, Puymirat E, Halim J, Karan R, van Gameren M, Terzić D, Milićević V, Tanter M, Pernot M, Goudot G
Lancet 2023 Dec 16;402(10419):2317-2325. Epub 2023 Nov 14 doi: 10.1016/S0140-6736(23)01518-0. PMID: 37972628
Doppler Echocardiographic Features of Pulmonary Vein Stenosis in Ex-Preterm Children.
Lin Y, Amin EK, Keller RL, Teitel DF, Nawaytou HM
J Am Soc Echocardiogr 2022 Apr;35(4):435-442. Epub 2022 Jan 2 doi: 10.1016/j.echo.2021.12.015. PMID: 34986343
Nifedipine increases fetoplacental perfusion.
Karahanoglu E, Altinboga O, Akpinar F, Demirdag E, Ozdemirci S, Akyol A, Yalvac S
J Perinat Med 2017 Jan 1;45(1):51-55. doi: 10.1515/jpm-2016-0072. PMID: 27387329
Exercise testing in asymptomatic severe aortic stenosis.
Magne J, Lancellotti P, Piérard LA
JACC Cardiovasc Imaging 2014 Feb;7(2):188-99. doi: 10.1016/j.jcmg.2013.08.011. PMID: 24524744

Diagnosis

Prevalence and Outcomes of Patients With Discordant High-Gradient Aortic Stenosis.
Unger P, Powers A, Le Nezet E, Lacasse-Rioux E, Galloo X, Clavel MA
J Am Coll Cardiol 2024 Mar 26;83(12):1109-1119. doi: 10.1016/j.jacc.2024.01.025. PMID: 38508842
The current diagnosis and treatment of patients with aortic valve stenosis.
Henning RJ
Future Cardiol 2021 Sep;17(6):1143-1160. Epub 2021 Mar 17 doi: 10.2217/fca-2020-0140. PMID: 33728942
The contemporary role of echocardiography in the assessment and management of aortic stenosis.
Kitai T, Tsutsui RS
J Med Ultrason (2001) 2020 Jan;47(1):71-80. Epub 2019 Dec 2 doi: 10.1007/s10396-019-00991-x. PMID: 31792637
Low-Gradient Aortic Stenosis: Solving the Conundrum Using Multi-Modality Imaging.
Messika-Zeitoun D, Oh JK, Topilsky Y, Burwash IG, Michelena HI, Enriquez-Sarano M
Prog Cardiovasc Dis 2018 Nov-Dec;61(5-6):416-422. Epub 2018 Nov 13 doi: 10.1016/j.pcad.2018.11.006. PMID: 30445161
Exercise testing in asymptomatic severe aortic stenosis.
Magne J, Lancellotti P, Piérard LA
JACC Cardiovasc Imaging 2014 Feb;7(2):188-99. doi: 10.1016/j.jcmg.2013.08.011. PMID: 24524744

Therapy

Treatment of severe symptomatic aortic valve stenosis using non-invasive ultrasound therapy: a cohort study.
Messas E, Ijsselmuiden A, Trifunović-Zamaklar D, Cholley B, Puymirat E, Halim J, Karan R, van Gameren M, Terzić D, Milićević V, Tanter M, Pernot M, Goudot G
Lancet 2023 Dec 16;402(10419):2317-2325. Epub 2023 Nov 14 doi: 10.1016/S0140-6736(23)01518-0. PMID: 37972628
Incidence and Risk Factors of Pannus after Mechanical Aortic Valve Replacement.
Choi JW, Hwang HY, Lee Y, Sohn SH, Kim KH, Kim KB, Ahn H
Thorac Cardiovasc Surg 2022 Apr;70(3):182-188. Epub 2021 May 3 doi: 10.1055/s-0041-1727152. PMID: 33940657
Low-Gradient Aortic Stenosis: Solving the Conundrum Using Multi-Modality Imaging.
Messika-Zeitoun D, Oh JK, Topilsky Y, Burwash IG, Michelena HI, Enriquez-Sarano M
Prog Cardiovasc Dis 2018 Nov-Dec;61(5-6):416-422. Epub 2018 Nov 13 doi: 10.1016/j.pcad.2018.11.006. PMID: 30445161
Nifedipine increases fetoplacental perfusion.
Karahanoglu E, Altinboga O, Akpinar F, Demirdag E, Ozdemirci S, Akyol A, Yalvac S
J Perinat Med 2017 Jan 1;45(1):51-55. doi: 10.1515/jpm-2016-0072. PMID: 27387329
Exercise testing in asymptomatic severe aortic stenosis.
Magne J, Lancellotti P, Piérard LA
JACC Cardiovasc Imaging 2014 Feb;7(2):188-99. doi: 10.1016/j.jcmg.2013.08.011. PMID: 24524744

Prognosis

Mean Pressure Gradient Prediction Based on Chest Angular Movements and Heart Rate Variability Parameters.
Shokouhmand A, Yang C, Aranoff ND, Driggin E, Green P, Tavassolian N
Annu Int Conf IEEE Eng Med Biol Soc 2021 Nov;2021:7170-7173. doi: 10.1109/EMBC46164.2021.9630805. PMID: 34892754
The contemporary role of echocardiography in the assessment and management of aortic stenosis.
Kitai T, Tsutsui RS
J Med Ultrason (2001) 2020 Jan;47(1):71-80. Epub 2019 Dec 2 doi: 10.1007/s10396-019-00991-x. PMID: 31792637
Low-Gradient Aortic Stenosis: Solving the Conundrum Using Multi-Modality Imaging.
Messika-Zeitoun D, Oh JK, Topilsky Y, Burwash IG, Michelena HI, Enriquez-Sarano M
Prog Cardiovasc Dis 2018 Nov-Dec;61(5-6):416-422. Epub 2018 Nov 13 doi: 10.1016/j.pcad.2018.11.006. PMID: 30445161
Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis.
Leng X, Lan L, Ip HL, Fan F, Ma SH, Ma K, Liu H, Yan Z, Liu J, Abrigo J, Soo YOY, Liebeskind DS, Wong KS, Leung TW
Eur J Neurol 2018 Feb;25(2):404-410. Epub 2017 Dec 18 doi: 10.1111/ene.13521. PMID: 29171118
Exercise testing in asymptomatic severe aortic stenosis.
Magne J, Lancellotti P, Piérard LA
JACC Cardiovasc Imaging 2014 Feb;7(2):188-99. doi: 10.1016/j.jcmg.2013.08.011. PMID: 24524744

Clinical prediction guides

Treatment of severe symptomatic aortic valve stenosis using non-invasive ultrasound therapy: a cohort study.
Messas E, Ijsselmuiden A, Trifunović-Zamaklar D, Cholley B, Puymirat E, Halim J, Karan R, van Gameren M, Terzić D, Milićević V, Tanter M, Pernot M, Goudot G
Lancet 2023 Dec 16;402(10419):2317-2325. Epub 2023 Nov 14 doi: 10.1016/S0140-6736(23)01518-0. PMID: 37972628
Mean Pressure Gradient Prediction Based on Chest Angular Movements and Heart Rate Variability Parameters.
Shokouhmand A, Yang C, Aranoff ND, Driggin E, Green P, Tavassolian N
Annu Int Conf IEEE Eng Med Biol Soc 2021 Nov;2021:7170-7173. doi: 10.1109/EMBC46164.2021.9630805. PMID: 34892754
Low-Gradient Aortic Stenosis: Solving the Conundrum Using Multi-Modality Imaging.
Messika-Zeitoun D, Oh JK, Topilsky Y, Burwash IG, Michelena HI, Enriquez-Sarano M
Prog Cardiovasc Dis 2018 Nov-Dec;61(5-6):416-422. Epub 2018 Nov 13 doi: 10.1016/j.pcad.2018.11.006. PMID: 30445161
Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis.
Leng X, Lan L, Ip HL, Fan F, Ma SH, Ma K, Liu H, Yan Z, Liu J, Abrigo J, Soo YOY, Liebeskind DS, Wong KS, Leung TW
Eur J Neurol 2018 Feb;25(2):404-410. Epub 2017 Dec 18 doi: 10.1111/ene.13521. PMID: 29171118
Exercise testing in asymptomatic severe aortic stenosis.
Magne J, Lancellotti P, Piérard LA
JACC Cardiovasc Imaging 2014 Feb;7(2):188-99. doi: 10.1016/j.jcmg.2013.08.011. PMID: 24524744

Recent systematic reviews

Outcomes of Ozaki Procedure/Aortic Valve Neocuspidization for Aortic Valve Diseases: A Systematic Review.
Badalyan SS, Markosyan SV, Ismailbaev AM, Asghar A, Ur Rehman A
Anatol J Cardiol 2023 Nov;27(11):619-627. doi: 10.14744/AnatolJCardiol.2023.3477. PMID: 37909351Free PMC Article
Improving accuracy in diagnosing aortic stenosis severity: An in-depth analysis of echocardiographic measurement error through literature review and simulation study.
Velders BJJ, Groenwold RHH, Ajmone Marsan N, Kappetein AP, Wijngaarden RAFLV, Braun J, Klautz RJM, Vriesendorp MD
Echocardiography 2023 Sep;40(9):892-902. Epub 2023 Jul 31 doi: 10.1111/echo.15664. PMID: 37519290
Hemodynamics and reverse remodeling associated with Mosaic, Perimount and Trifecta aortic bioprostheses.
Kalogerakos PD, Kontopodis N, Ioannou CV, Kladou E, Chalkiadakis G, Athanasiou T, Lazopoulos G
Expert Rev Med Devices 2019 Aug;16(8):743-751. Epub 2019 Jul 18 doi: 10.1080/17434440.2019.1642105. PMID: 31318302
Effects of Aortic Valve Replacement on Severe Aortic Stenosis and Preserved Systolic Function: Systematic Review and Network Meta-analysis.
Zheng Q, Djohan AH, Lim E, Ding ZP, Ling LH, Shi L, Chan ES, Chin CWL
Sci Rep 2017 Jul 11;7(1):5092. doi: 10.1038/s41598-017-05021-9. PMID: 28698585Free PMC Article
Transcatheter aortic valve implantation for high-risk patients with severe aortic stenosis: A systematic review.
Yan TD, Cao C, Martens-Nielsen J, Padang R, Ng M, Vallely MP, Bannon PG
J Thorac Cardiovasc Surg 2010 Jun;139(6):1519-28. Epub 2009 Oct 28 doi: 10.1016/j.jtcvs.2009.08.037. PMID: 19846124

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