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Dimensionless Index

MedGen UID:
1640578
•Concept ID:
C4687740
•
Finding

Definition

The ratio of the left ventricular outflow tract (LVOT) velocity to the maximum velocity of the aortic valve. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDimensionless Index

Professional guidelines

PubMed

Electrocardiographic criteria for vagotonia-validation with pharmacological parasympathetic blockade in healthy subjects.
Lazzoli JK, Soares PP, da Nóbrega AC, de Araújo CG
Int J Cardiol 2003 Feb;87(2-3):231-6. doi: 10.1016/s0167-5273(02)00330-3. PMID: 12559544

Recent clinical studies

Etiology

Dimensionless index and outcome in patients with aortic valve disease.
Leibowitz D, Zwas D, Elbaz-Greener G, Planer D, Alcalai R, Gotsman I
Echocardiography 2024 Jun;41(6):e15848. doi: 10.1111/echo.15848. PMID: 38814015
Large-Scale Proteomics Identifies Novel Biomarkers and Circulating Risk Factors for Aortic Stenosis.
Shelbaya K, Arthur V, Yang Y, Dorbala P, Buckley L, Claggett B, Skali H, Dufresne L, Yang TY, Engert JC, Thanassoulis G, Floyd J, Austin TR, Bortnick A, Kizer J, Freitas RCC, Singh SA, Aikawa E, Hoogeveen RC, Ballantyne C, Yu B, Coresh J, Blaha MJ, Matsushita K, Shah AM
J Am Coll Cardiol 2024 Feb 6;83(5):577-591. doi: 10.1016/j.jacc.2023.11.021. PMID: 38296402
Combined Value of Dimensionless Index and Transvalvular Flow Rate in Risk Stratification of Aortic Stenosis.
Namasivayam M, Churchill TW, Capoulade R, Pibarot P, Danik JS, Picard MH, Levine RA, Hung J
Am J Cardiol 2024 Feb 15;213:69-71. Epub 2023 Dec 15 doi: 10.1016/j.amjcard.2023.12.008. PMID: 38103765Free PMC Article
Mitral Annular Calcification and Calcific Mitral Stenosis: Role of Echocardiography in Hemodynamic Assessment and Management.
Silbiger JJ
J Am Soc Echocardiogr 2021 Sep;34(9):923-931. Epub 2021 Apr 20 doi: 10.1016/j.echo.2021.04.007. PMID: 33857624
Dimensionless Index in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Ejection Fraction.
Altes A, Thellier N, Rusinaru D, Marsou W, Bohbot Y, Chadha G, Leman B, Paquet P, Ennezat PV, Tribouilloy C, Maréchaux S
Circ Cardiovasc Imaging 2020 Oct;13(10):e010925. Epub 2020 Oct 20 doi: 10.1161/CIRCIMAGING.120.010925. PMID: 33076698

Diagnosis

Dimensionless index and outcome in patients with aortic valve disease.
Leibowitz D, Zwas D, Elbaz-Greener G, Planer D, Alcalai R, Gotsman I
Echocardiography 2024 Jun;41(6):e15848. doi: 10.1111/echo.15848. PMID: 38814015
Combined Value of Dimensionless Index and Transvalvular Flow Rate in Risk Stratification of Aortic Stenosis.
Namasivayam M, Churchill TW, Capoulade R, Pibarot P, Danik JS, Picard MH, Levine RA, Hung J
Am J Cardiol 2024 Feb 15;213:69-71. Epub 2023 Dec 15 doi: 10.1016/j.amjcard.2023.12.008. PMID: 38103765Free PMC Article
Dimensionless Index in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Ejection Fraction.
Altes A, Thellier N, Rusinaru D, Marsou W, Bohbot Y, Chadha G, Leman B, Paquet P, Ennezat PV, Tribouilloy C, Maréchaux S
Circ Cardiovasc Imaging 2020 Oct;13(10):e010925. Epub 2020 Oct 20 doi: 10.1161/CIRCIMAGING.120.010925. PMID: 33076698
Relation of Dimensionless Index to Long-Term Outcome in Aortic Stenosis With Preserved LVEF.
Rusinaru D, Malaquin D, Maréchaux S, Debry N, Tribouilloy C
JACC Cardiovasc Imaging 2015 Jul;8(7):766-75. Epub 2015 Jun 17 doi: 10.1016/j.jcmg.2015.01.023. PMID: 26093931
Clinical applications of strain rate imaging.
Yip G, Abraham T, Belohlavek M, Khandheria BK
J Am Soc Echocardiogr 2003 Dec;16(12):1334-42. doi: 10.1067/j.echo.2003.09.004. PMID: 14652617

Therapy

Large-Scale Proteomics Identifies Novel Biomarkers and Circulating Risk Factors for Aortic Stenosis.
Shelbaya K, Arthur V, Yang Y, Dorbala P, Buckley L, Claggett B, Skali H, Dufresne L, Yang TY, Engert JC, Thanassoulis G, Floyd J, Austin TR, Bortnick A, Kizer J, Freitas RCC, Singh SA, Aikawa E, Hoogeveen RC, Ballantyne C, Yu B, Coresh J, Blaha MJ, Matsushita K, Shah AM
J Am Coll Cardiol 2024 Feb 6;83(5):577-591. doi: 10.1016/j.jacc.2023.11.021. PMID: 38296402
The Effect of Dobutamine Stress Testing on Vortex Formation Time in Patients Evaluated for Ischemia.
Dimitroglou Y, Aggeli C, Rapis K, Maragiannis D, Polytarchou K, Gatzoulis K, Tsiamis E, Tousoulis D
J Cardiovasc Transl Res 2021 Aug;14(4):735-743. Epub 2020 Apr 6 doi: 10.1007/s12265-020-09998-z. PMID: 32253745
Doppler assessment of aortic stenosis: a 25-operator study demonstrating why reading the peak velocity is superior to velocity time integral.
Sacchi S, Dhutia NM, Shun-Shin MJ, Zolgharni M, Sutaria N, Francis DP, Cole GD
Eur Heart J Cardiovasc Imaging 2018 Dec 1;19(12):1380-1389. doi: 10.1093/ehjci/jex218. PMID: 29346531Free PMC Article
The thermal dose index.
Ziskin MC
J Ultrasound Med 2010 Oct;29(10):1475-9. doi: 10.7863/jum.2010.29.10.1475. PMID: 20876902
Narcotrend index versus bispectral index as electroencephalogram measures of anesthetic drug effect during propofol anesthesia.
Kreuer S, Wilhelm W, Grundmann U, Larsen R, Bruhn J
Anesth Analg 2004 Mar;98(3):692-7, table of contents. doi: 10.1213/01.ane.0000103182.78466.ef. PMID: 14980921

Prognosis

Dimensionless index and outcome in patients with aortic valve disease.
Leibowitz D, Zwas D, Elbaz-Greener G, Planer D, Alcalai R, Gotsman I
Echocardiography 2024 Jun;41(6):e15848. doi: 10.1111/echo.15848. PMID: 38814015
Combined Value of Dimensionless Index and Transvalvular Flow Rate in Risk Stratification of Aortic Stenosis.
Namasivayam M, Churchill TW, Capoulade R, Pibarot P, Danik JS, Picard MH, Levine RA, Hung J
Am J Cardiol 2024 Feb 15;213:69-71. Epub 2023 Dec 15 doi: 10.1016/j.amjcard.2023.12.008. PMID: 38103765Free PMC Article
Dimensionless Index in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Ejection Fraction.
Altes A, Thellier N, Rusinaru D, Marsou W, Bohbot Y, Chadha G, Leman B, Paquet P, Ennezat PV, Tribouilloy C, Maréchaux S
Circ Cardiovasc Imaging 2020 Oct;13(10):e010925. Epub 2020 Oct 20 doi: 10.1161/CIRCIMAGING.120.010925. PMID: 33076698
Predicting Outcomes in Patients With AsymptomaticModerate to Severe Aortic Stenosis.
Bahler RC, Hawi R, Rovner A, Finkelhor RS, Thomas CL, Dawson NV
Am J Cardiol 2018 Sep 1;122(5):851-858. Epub 2018 Jun 4 doi: 10.1016/j.amjcard.2018.05.027. PMID: 30037422
Relation of Dimensionless Index to Long-Term Outcome in Aortic Stenosis With Preserved LVEF.
Rusinaru D, Malaquin D, Maréchaux S, Debry N, Tribouilloy C
JACC Cardiovasc Imaging 2015 Jul;8(7):766-75. Epub 2015 Jun 17 doi: 10.1016/j.jcmg.2015.01.023. PMID: 26093931

Clinical prediction guides

Combined Value of Dimensionless Index and Transvalvular Flow Rate in Risk Stratification of Aortic Stenosis.
Namasivayam M, Churchill TW, Capoulade R, Pibarot P, Danik JS, Picard MH, Levine RA, Hung J
Am J Cardiol 2024 Feb 15;213:69-71. Epub 2023 Dec 15 doi: 10.1016/j.amjcard.2023.12.008. PMID: 38103765Free PMC Article
Optimal vortex formation time index in mitral valve stenosis.
Ambhore A, Ngiam JN, Chew NWS, Pramotedham T, Loh JPY, Kang GS, Poh KK
Int J Cardiovasc Imaging 2021 May;37(5):1595-1600. Epub 2021 Jan 12 doi: 10.1007/s10554-020-02140-9. PMID: 33433748
Dimensionless Index in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Ejection Fraction.
Altes A, Thellier N, Rusinaru D, Marsou W, Bohbot Y, Chadha G, Leman B, Paquet P, Ennezat PV, Tribouilloy C, Maréchaux S
Circ Cardiovasc Imaging 2020 Oct;13(10):e010925. Epub 2020 Oct 20 doi: 10.1161/CIRCIMAGING.120.010925. PMID: 33076698
Predicting Outcomes in Patients With AsymptomaticModerate to Severe Aortic Stenosis.
Bahler RC, Hawi R, Rovner A, Finkelhor RS, Thomas CL, Dawson NV
Am J Cardiol 2018 Sep 1;122(5):851-858. Epub 2018 Jun 4 doi: 10.1016/j.amjcard.2018.05.027. PMID: 30037422
Relation of Dimensionless Index to Long-Term Outcome in Aortic Stenosis With Preserved LVEF.
Rusinaru D, Malaquin D, Maréchaux S, Debry N, Tribouilloy C
JACC Cardiovasc Imaging 2015 Jul;8(7):766-75. Epub 2015 Jun 17 doi: 10.1016/j.jcmg.2015.01.023. PMID: 26093931

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