Plasma/serum xenobiotic

MedGen UID:: 1642103
•Concept ID:: C4703719
•: Finding

HPO:	HP:0500100

Definition

Presence of a xenobiotic in plasma and/or serum. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPlasma/serum xenobiotic

Phenotypic abnormality
- Abnormality of metabolism/homeostasis
  - Presence of xenobiotic
    - Blood xenobiotic
      - Plasma/serum xenobiotic
        Positive methadone plasma/serum test
        Positive plasma/serum cotinine test

Recent clinical studies

Etiology

Novel Transgenic Mouse Model for Studying Human Serum Albumin as a Biomarker of Carcinogenic Exposure.

Sheng J, Wang Y, Turesky RJ, Kluetzman K, Zhang QY, Ding X
Chem Res Toxicol 2016 May 16;29(5):797-809. Epub 2016 Apr 14 doi: 10.1021/acs.chemrestox.5b00529. PMID: 27028147 Free PMC Article

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Diagnosis

Aryl hydrocarbon receptor (AhR) agonists increase airway epithelial matrix metalloproteinase activity.

Tsai MJ, Hsu YL, Wang TN, Wu LY, Lien CT, Hung CH, Kuo PL, Huang MS
J Mol Med (Berl) 2014 Jun;92(6):615-28. Epub 2014 Jan 28 doi: 10.1007/s00109-014-1121-x. PMID: 24469321

Measurement of xenobiotics in saliva: is saliva an attractive alternative matrix? Case studies and analytical perspectives.

Mullangi R, Agrawal S, Srinivas NR
Biomed Chromatogr 2009 Jan;23(1):3-25. doi: 10.1002/bmc.1103. PMID: 18816455

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