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Cardiac Extraskeletal Osteosarcoma

MedGen UID:
1643049
•Concept ID:
C4687638
•
Neoplastic Process
Synonyms: Cardiac Osteogenic Sarcoma; Cardiac Osteosarcoma; Heart Extraskeletal Osteosarcoma

Definition

An extraskeletal osteosarcoma that arises from the heart. It produces osteoid and bone, and occasionally shows chondroblastic differentiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac Extraskeletal Osteosarcoma

Recent clinical studies

Diagnosis

Postradiation Extraskeletal Osteosarcoma Masquerading as an Axillary Artery Pseudoaneurysm.
Wohlauer M, McKenney JK, Park WM
Ann Vasc Surg 2016 Jan;30:157.e7-9. Epub 2015 Aug 17 doi: 10.1016/j.avsg.2015.06.069. PMID: 26291499
Extraskeletal chondroblastic osteosarcoma in the left atrium.
Korkmaz Ö, Göksel S, Eğilmez HR, Berkan Ö
Interact Cardiovasc Thorac Surg 2014 Dec;19(6):1077-9. Epub 2014 Sep 8 doi: 10.1093/icvts/ivu298. PMID: 25205782
Primary extraskeletal Ewing's sarcoma of the lung.
Hancorn K, Sharma A, Shackcloth M
Interact Cardiovasc Thorac Surg 2010 May;10(5):803-4. Epub 2010 Jan 12 doi: 10.1510/icvts.2009.216952. PMID: 20067987
Multiple cardiac metastases from Ewing's sarcoma.
Chandramohan NK, Hussain MB, Nayak N, Kattoor J, Pandey M, Krishnankutty R
Can J Cardiol 2005 May 1;21(6):525-7. PMID: 15917882
Primary cardiac osteosarcoma: multidisciplinary aspects applicable to extraskeletal osteosarcoma generally.
Schneiderman H, Fordham EW, Goren CC, McCall AR, Rosenberg MS, Rozek S
CA Cancer J Clin 1984 Mar-Apr;34(2):110-7. doi: 10.3322/canjclin.34.2.110. PMID: 6423218

Therapy

Pediatric Extraskeletal Ewing Sarcoma Originating in the Heart: A Case Report and Review of the Literature.
Buffoni I, Nuri H, Pome' G, Sementa AR, Stagnaro N, Barra S, Manzitti C, Garaventa A
J Pediatr Hematol Oncol 2021 May 1;43(4):147-151. doi: 10.1097/MPH.0000000000001622. PMID: 31688622
Multiple cardiac metastases from Ewing's sarcoma.
Chandramohan NK, Hussain MB, Nayak N, Kattoor J, Pandey M, Krishnankutty R
Can J Cardiol 2005 May 1;21(6):525-7. PMID: 15917882
Extraskeletal Ewing's sarcoma with fatal cardiac metastasis.
Flinn RM, Foyle A, Montague TJ
CMAJ 1985 Nov 15;133(10):1017-8. PMID: 4063900Free PMC Article

Prognosis

Extraskeletal chondroblastic osteosarcoma in the left atrium.
Korkmaz Ö, Göksel S, Eğilmez HR, Berkan Ö
Interact Cardiovasc Thorac Surg 2014 Dec;19(6):1077-9. Epub 2014 Sep 8 doi: 10.1093/icvts/ivu298. PMID: 25205782
Primary extraskeletal Ewing's sarcoma of the lung.
Hancorn K, Sharma A, Shackcloth M
Interact Cardiovasc Thorac Surg 2010 May;10(5):803-4. Epub 2010 Jan 12 doi: 10.1510/icvts.2009.216952. PMID: 20067987
Extraskeletal Ewing's sarcoma of primary cardiac origin.
Higgins JC, Katzman PJ, Yeager SB, Dickerman JD, Leavitt BJ, Tischler MD, Battle RW
Pediatr Cardiol 1994 Jul-Aug;15(4):207-8. doi: 10.1007/BF00800678. PMID: 7991441

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