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Sickle Cell Chronic Lung Disease

MedGen UID:
1649262
•Concept ID:
C4743984
•
Disease or Syndrome

Definition

A pulmonary complication of sickle cell disease characterized by radiographic interstitial abnormalities and impaired pulmonary function. In severe cases, pulmonary hypertension is present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSickle Cell Chronic Lung Disease

Professional guidelines

PubMed

Chronic sickle cell lung disease: new insights into the diagnosis, pathogenesis and treatment of pulmonary hypertension.
Machado RF, Gladwin MT
Br J Haematol 2005 May;129(4):449-64. doi: 10.1111/j.1365-2141.2005.05432.x. PMID: 15877728

Recent clinical studies

Etiology

Sickle cell chronic lung disease among young adult Nigerians.
Fawibe AE, Oluboyo PO, Salami AK
West Afr J Med 2010 Jan-Feb;29(1):30-3. doi: 10.4314/wajm.v29i1.55948. PMID: 20496335
Sickle cell chronic lung disease: prior morbidity and the risk of pulmonary failure.
Powars D, Weidman JA, Odom-Maryon T, Niland JC, Johnson C
Medicine (Baltimore) 1988 Jan;67(1):66-76. PMID: 3336282

Diagnosis

Sickle cell chronic lung disease among young adult Nigerians.
Fawibe AE, Oluboyo PO, Salami AK
West Afr J Med 2010 Jan-Feb;29(1):30-3. doi: 10.4314/wajm.v29i1.55948. PMID: 20496335
Pulmonary manifestations of sickle cell disease.
Siddiqui AK, Ahmed S
Postgrad Med J 2003 Jul;79(933):384-90. doi: 10.1136/pmj.79.933.384. PMID: 12897216Free PMC Article
Sickle cell disease: the clinical manifestations.
Childs JW
J Am Osteopath Assoc 1995 Oct;95(10):593-8. PMID: 8557548
Sickle cell chronic lung disease: prior morbidity and the risk of pulmonary failure.
Powars D, Weidman JA, Odom-Maryon T, Niland JC, Johnson C
Medicine (Baltimore) 1988 Jan;67(1):66-76. PMID: 3336282

Prognosis

Maternal death due to sickle cell chronic lung disease.
Van Enk A, Visschers G, Jansen W, Statius van Eps LW
Br J Obstet Gynaecol 1992 Feb;99(2):162-3. doi: 10.1111/j.1471-0528.1992.tb14480.x. PMID: 1554673
Sickle cell chronic lung disease: prior morbidity and the risk of pulmonary failure.
Powars D, Weidman JA, Odom-Maryon T, Niland JC, Johnson C
Medicine (Baltimore) 1988 Jan;67(1):66-76. PMID: 3336282

Clinical prediction guides

Sickle cell chronic lung disease: prior morbidity and the risk of pulmonary failure.
Powars D, Weidman JA, Odom-Maryon T, Niland JC, Johnson C
Medicine (Baltimore) 1988 Jan;67(1):66-76. PMID: 3336282

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