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Thyroid Gland Rosai-Dorfman Disease

MedGen UID:
1652154
•Concept ID:
C4744803
•
Disease or Syndrome
Synonym: Thyroid Gland Sinus Histiocytosis with Massive Lymphadenopathy

Definition

Sinus histiocytosis with massive lymphadenopathy affecting the thyroid gland. It is rare and is usually accompanied by involvement of cervical lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThyroid Gland Rosai-Dorfman Disease

Recent clinical studies

Etiology

Adult Orbital Lesions in Saudi Arabia: A Multi-centered Demographic Study with Clinicopathological Correlation.
Alsalamah AK, Maktabi AM, Alkatan HM
J Epidemiol Glob Health 2020 Dec;10(4):359-366. Epub 2020 Jul 29 doi: 10.2991/jegh.k.200720.001. PMID: 32959608Free PMC Article

Diagnosis

Cytologic and histological features of rare nonepithelial and nonlymphoid tumors of the thyroid.
Rossi ED, Pantanowitz L, Hornick JL
Cancer Cytopathol 2021 Aug;129(8):583-602. Epub 2021 Jan 25 doi: 10.1002/cncy.22404. PMID: 33493367
Thyroid Rosai-Dorfman disease with infiltration of IgG4-bearing plasma cells associated with multiple small pulmonary cysts.
Gianella P, Dulguerov N, Arnoux G, Pusztaszeri M, Seebach JD
BMC Pulm Med 2019 May 3;19(1):83. doi: 10.1186/s12890-019-0847-1. PMID: 31053123Free PMC Article
Thyroid involvement by Rosai-Dorfman disease.
Palmas Candia F, Porras Ledantes JA, Raventós Estellé A, Simón Muela I, Vendrell Ortega J, Näf Cortés S
Endocrinol Diabetes Nutr 2017 May;64(5):280-281. Epub 2017 Mar 17 doi: 10.1016/j.endinu.2017.01.002. PMID: 29056254
Rosai-Dorfman disease.
Santra G, Das BK, Mandal B, Kundu SS, Bandopadhyay A
Singapore Med J 2010 Oct;51(10):e173-5. PMID: 21103807
Thyroid involvement in Rosai-Dorfman disease.
Lee FY, Jan YJ, Chou G, Wang J, Wang CC
Thyroid 2007 May;17(5):471-6. doi: 10.1089/thy.2006.0192. PMID: 17542678

Therapy

BRAF gene mutations in synchronous papillary thyroid carcinoma and Langerhans cell histiocytosis co-existing in the thyroid gland: a case report and literature review.
A Al Hamad M, Albisher HM, Al Saeed WR, Almumtin AT, Allabbad FM, A Shawarby M
BMC Cancer 2019 Feb 22;19(1):170. doi: 10.1186/s12885-019-5372-3. PMID: 30795755Free PMC Article
Thyroid involvement by Rosai-Dorfman disease.
Palmas Candia F, Porras Ledantes JA, Raventós Estellé A, Simón Muela I, Vendrell Ortega J, Näf Cortés S
Endocrinol Diabetes Nutr 2017 May;64(5):280-281. Epub 2017 Mar 17 doi: 10.1016/j.endinu.2017.01.002. PMID: 29056254
Cold thyroid nodule as the sole manifestation of Rosai-Dorfman disease with mild lymphadenopathy, coexisting with chronic autoimmune thyroiditis.
Tamouridis N, Deladetsima JK, Kastanias I, Delis S, Bramis J, Zerva CA, Anapliotou ML
J Endocrinol Invest 1999 Dec;22(11):866-70. doi: 10.1007/BF03343661. PMID: 10710276

Prognosis

Adult Orbital Lesions in Saudi Arabia: A Multi-centered Demographic Study with Clinicopathological Correlation.
Alsalamah AK, Maktabi AM, Alkatan HM
J Epidemiol Glob Health 2020 Dec;10(4):359-366. Epub 2020 Jul 29 doi: 10.2991/jegh.k.200720.001. PMID: 32959608Free PMC Article
Thyroid Rosai-Dorfman disease with infiltration of IgG4-bearing plasma cells associated with multiple small pulmonary cysts.
Gianella P, Dulguerov N, Arnoux G, Pusztaszeri M, Seebach JD
BMC Pulm Med 2019 May 3;19(1):83. doi: 10.1186/s12890-019-0847-1. PMID: 31053123Free PMC Article

Clinical prediction guides

Adult Orbital Lesions in Saudi Arabia: A Multi-centered Demographic Study with Clinicopathological Correlation.
Alsalamah AK, Maktabi AM, Alkatan HM
J Epidemiol Glob Health 2020 Dec;10(4):359-366. Epub 2020 Jul 29 doi: 10.2991/jegh.k.200720.001. PMID: 32959608Free PMC Article
Cold thyroid nodule as the sole manifestation of Rosai-Dorfman disease with mild lymphadenopathy, coexisting with chronic autoimmune thyroiditis.
Tamouridis N, Deladetsima JK, Kastanias I, Delis S, Bramis J, Zerva CA, Anapliotou ML
J Endocrinol Invest 1999 Dec;22(11):866-70. doi: 10.1007/BF03343661. PMID: 10710276

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