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Unresectable Bone Sarcoma

MedGen UID:
1653542
•Concept ID:
C4727006
•
Neoplastic Process

Definition

Bone sarcoma that is not amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

Radiotherapy in bone sarcoma: the quest for better treatment option.
Locquet MA, Brahmi M, Blay JY, Dutour A
BMC Cancer 2023 Aug 11;23(1):742. doi: 10.1186/s12885-023-11232-3. PMID: 37563551Free PMC Article
Biology and Management of High-Grade Chondrosarcoma: An Update on Targets and Treatment Options.
Tlemsani C, Larousserie F, De Percin S, Audard V, Hadjadj D, Chen J, Biau D, Anract P, Terris B, Goldwasser F, Pasmant E, Boudou-Rouquette P
Int J Mol Sci 2023 Jan 10;24(2) doi: 10.3390/ijms24021361. PMID: 36674874Free PMC Article
Efficacy of trabectedin for the treatment of liposarcoma.
Zijoo R, von Mehren M
Expert Opin Pharmacother 2016 Oct;17(14):1953-62. Epub 2016 Sep 15 doi: 10.1080/14656566.2016.1229304. PMID: 27615729

Recent clinical studies

Etiology

Local surgery feasibility and safety after carbon ion radiotherapy for primary bone sarcomas.
Sabe H, Outani H, Imura Y, Takami H, Nakai T, Takenaka S, Kakunaga S, Tamiya H, Wakamatsu T, Nakai S, Demizu Y, Imai R, Okada S
J Orthop Sci 2024 May;29(3):903-907. Epub 2023 Apr 10 doi: 10.1016/j.jos.2023.03.016. PMID: 37045686

Therapy

Local surgery feasibility and safety after carbon ion radiotherapy for primary bone sarcomas.
Sabe H, Outani H, Imura Y, Takami H, Nakai T, Takenaka S, Kakunaga S, Tamiya H, Wakamatsu T, Nakai S, Demizu Y, Imai R, Okada S
J Orthop Sci 2024 May;29(3):903-907. Epub 2023 Apr 10 doi: 10.1016/j.jos.2023.03.016. PMID: 37045686
Isolated limb perfusion with tumour necrosis factor-alpha and melphalan for unresectable bone sarcomas of the lower extremity.
Bickels J, Manusama ER, Gutman M, Eggermont AM, Kollender Y, Abu-Abid S, Van Geel AN, Lev-Shlush D, Klausner JM, Meller I
Eur J Surg Oncol 1999 Oct;25(5):509-14. doi: 10.1053/ejso.1999.0687. PMID: 10527599

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    • PMC Articles
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