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Infantile Apnea, AE

MedGen UID:
1653576
•Concept ID:
C4722413
•
Finding
Synonym: Infantile Apnea, Adverse Event

Definition

An adverse event in a newborn characterized by cessation of air flow. [from NCI]

Professional guidelines

PubMed

Osteopathic manipulative treatment for pediatric conditions: a systematic review.
Posadzki P, Lee MS, Ernst E
Pediatrics 2013 Jul;132(1):140-52. Epub 2013 Jun 17 doi: 10.1542/peds.2012-3959. PMID: 23776117
Acetazolamide treatment for infantile central sleep apnea.
Philippi H, Bieber I, Reitter B
J Child Neurol 2001 Aug;16(8):600-3. doi: 10.1177/088307380101600813. PMID: 11510934
Lorazepam in the treatment of refractory neonatal seizures.
Maytal J, Novak GP, King KC
J Child Neurol 1991 Oct;6(4):319-23. doi: 10.1177/088307389100600406. PMID: 1940133

Recent clinical studies

Etiology

Caffeine disrupts ataxia telangiectasia mutated gene-related pathways and exacerbates acetaminophen toxicity in human fetal immortalized hepatocytes.
Viswanathan P, Gupta P, Sharma Y, Maisuradze L, Bandi S, Gupta S
Toxicology 2021 Jun 15;457:152811. Epub 2021 May 7 doi: 10.1016/j.tox.2021.152811. PMID: 33971260
Adverse Events in Young and Preterm Infants Receiving Topical Timolol for Infantile Hemangioma.
Frommelt P, Juern A, Siegel D, Holland K, Seefeldt M, Yu J, Uhing M, Wade K, Drolet B
Pediatr Dermatol 2016 Jul;33(4):405-14. Epub 2016 May 31 doi: 10.1111/pde.12869. PMID: 27246751
Risk of Occupational Accidents in Workers with Obstructive Sleep Apnea: Systematic Review and Meta-analysis.
Garbarino S, Guglielmi O, Sanna A, Mancardi GL, Magnavita N
Sleep 2016 Jun 1;39(6):1211-8. doi: 10.5665/sleep.5834. PMID: 26951401Free PMC Article
Osteopathic manipulative treatment for pediatric conditions: a systematic review.
Posadzki P, Lee MS, Ernst E
Pediatrics 2013 Jul;132(1):140-52. Epub 2013 Jun 17 doi: 10.1542/peds.2012-3959. PMID: 23776117
Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study.
Toubas PL, Duke JC, McCaffree MA, Mattice CD, Bendell D, Orr WC
Pediatrics 1986 Jul;78(1):159-63. PMID: 3725488

Diagnosis

Risk of Occupational Accidents in Workers with Obstructive Sleep Apnea: Systematic Review and Meta-analysis.
Garbarino S, Guglielmi O, Sanna A, Mancardi GL, Magnavita N
Sleep 2016 Jun 1;39(6):1211-8. doi: 10.5665/sleep.5834. PMID: 26951401Free PMC Article
Startle epilepsy associated with infantile hemiplegia (SEIH): video-polygraphic features and long-term outcome.
d'Orsi G, Demaio V, Operto F, Auricchio G, Minervini MG, Coppola G
Neuropediatrics 2009 Apr;40(2):97-100. Epub 2009 Oct 6 doi: 10.1055/s-0029-1237722. PMID: 19809941
Infant botulism intoxication and autonomic nervous system dysfunction.
Patural H, Goffaux P, Paricio C, Emeriaud G, Teyssier G, Barthelemy JC, Pichot V, Roche F
Anaerobe 2009 Oct;15(5):197-200. Epub 2009 Mar 25 doi: 10.1016/j.anaerobe.2009.03.004. PMID: 19327405
Lorazepam in the treatment of refractory neonatal seizures.
Maytal J, Novak GP, King KC
J Child Neurol 1991 Oct;6(4):319-23. doi: 10.1177/088307389100600406. PMID: 1940133

Therapy

Manual therapy for the pediatric population: a systematic review.
Parnell Prevost C, Gleberzon B, Carleo B, Anderson K, Cark M, Pohlman KA
BMC Complement Altern Med 2019 Mar 13;19(1):60. doi: 10.1186/s12906-019-2447-2. PMID: 30866915Free PMC Article
Adverse Events in Young and Preterm Infants Receiving Topical Timolol for Infantile Hemangioma.
Frommelt P, Juern A, Siegel D, Holland K, Seefeldt M, Yu J, Uhing M, Wade K, Drolet B
Pediatr Dermatol 2016 Jul;33(4):405-14. Epub 2016 May 31 doi: 10.1111/pde.12869. PMID: 27246751
Osteopathic manipulative treatment for pediatric conditions: a systematic review.
Posadzki P, Lee MS, Ernst E
Pediatrics 2013 Jul;132(1):140-52. Epub 2013 Jun 17 doi: 10.1542/peds.2012-3959. PMID: 23776117
Acetazolamide treatment for infantile central sleep apnea.
Philippi H, Bieber I, Reitter B
J Child Neurol 2001 Aug;16(8):600-3. doi: 10.1177/088307380101600813. PMID: 11510934
Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study.
Toubas PL, Duke JC, McCaffree MA, Mattice CD, Bendell D, Orr WC
Pediatrics 1986 Jul;78(1):159-63. PMID: 3725488

Prognosis

Startle epilepsy associated with infantile hemiplegia (SEIH): video-polygraphic features and long-term outcome.
d'Orsi G, Demaio V, Operto F, Auricchio G, Minervini MG, Coppola G
Neuropediatrics 2009 Apr;40(2):97-100. Epub 2009 Oct 6 doi: 10.1055/s-0029-1237722. PMID: 19809941
Acetazolamide treatment for infantile central sleep apnea.
Philippi H, Bieber I, Reitter B
J Child Neurol 2001 Aug;16(8):600-3. doi: 10.1177/088307380101600813. PMID: 11510934
"Nautral" canine model of infantile hydrocephalus.
Kaufman HH, Dujovny M, Huchton JD, Kossovsky N, Miller M, Carmel PC
Neurosurgery 1980 Feb;6(2):142-8. doi: 10.1227/00006123-198002000-00005. PMID: 7366806

Clinical prediction guides

Infant botulism intoxication and autonomic nervous system dysfunction.
Patural H, Goffaux P, Paricio C, Emeriaud G, Teyssier G, Barthelemy JC, Pichot V, Roche F
Anaerobe 2009 Oct;15(5):197-200. Epub 2009 Mar 25 doi: 10.1016/j.anaerobe.2009.03.004. PMID: 19327405
Lorazepam in the treatment of refractory neonatal seizures.
Maytal J, Novak GP, King KC
J Child Neurol 1991 Oct;6(4):319-23. doi: 10.1177/088307389100600406. PMID: 1940133

Recent systematic reviews

Manual therapy for the pediatric population: a systematic review.
Parnell Prevost C, Gleberzon B, Carleo B, Anderson K, Cark M, Pohlman KA
BMC Complement Altern Med 2019 Mar 13;19(1):60. doi: 10.1186/s12906-019-2447-2. PMID: 30866915Free PMC Article
Risk of Occupational Accidents in Workers with Obstructive Sleep Apnea: Systematic Review and Meta-analysis.
Garbarino S, Guglielmi O, Sanna A, Mancardi GL, Magnavita N
Sleep 2016 Jun 1;39(6):1211-8. doi: 10.5665/sleep.5834. PMID: 26951401Free PMC Article
Osteopathic manipulative treatment for pediatric conditions: a systematic review.
Posadzki P, Lee MS, Ernst E
Pediatrics 2013 Jul;132(1):140-52. Epub 2013 Jun 17 doi: 10.1542/peds.2012-3959. PMID: 23776117

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