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Supratentorial Pleomorphic Xanthoastrocytoma

MedGen UID:
1660183
•Concept ID:
C4744526
•
Neoplastic Process

Definition

A pleomorphic xanthoastrocytoma that arises from the supratentorial region of the brain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSupratentorial Pleomorphic Xanthoastrocytoma

Professional guidelines

PubMed

Clinical Features, Treatment and Outcome of Childhood Glial Tumors.
Kara B, Ertan K, Karabagli P, Karabagli H, Yavas G, Caglayan AO, Koksal Y
Turk Neurosurg 2022;32(1):135-142. doi: 10.5137/1019-5149.JTN.34801-21.2. PMID: 34751424
Hub biomarkers for the diagnosis and treatment of glioblastoma based on microarray technology.
Cui K, Chen JH, Zou YF, Zhang SY, Wu B, Jing K, Li LW, Xia L, Sun C, Dong YL
Technol Cancer Res Treat 2021 Jan-Dec;20:1533033821990368. doi: 10.1177/1533033821990368. PMID: 34018447Free PMC Article
Thalamic Glioblastoma: Clinical Presentation, Management Strategies, and Outcomes.
Esquenazi Y, Moussazadeh N, Link TW, Hovinga KE, Reiner AS, DiStefano NM, Brennan C, Gutin P, Tabar V
Neurosurgery 2018 Jul 1;83(1):76-85. doi: 10.1093/neuros/nyx349. PMID: 28973417Free PMC Article

Recent clinical studies

Etiology

Clinical Features, Treatment and Outcome of Childhood Glial Tumors.
Kara B, Ertan K, Karabagli P, Karabagli H, Yavas G, Caglayan AO, Koksal Y
Turk Neurosurg 2022;32(1):135-142. doi: 10.5137/1019-5149.JTN.34801-21.2. PMID: 34751424
Differentiation between supratentorial pilocytic astrocytoma and extraventricular ependymoma using multiparametric MRI.
Zhou X, Su Y, Huang W, Lin X, Xing Z, Cao D
Acta Radiol 2022 Dec;63(12):1661-1668. Epub 2021 Oct 28 doi: 10.1177/02841851211054195. PMID: 34709088
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article
Pleomorphic xanthoastrocytoma of childhood: MR imaging and diffusion MR imaging features.
Moore W, Mathis D, Gargan L, Bowers DC, Klesse LJ, Margraf L, Koral K
AJNR Am J Neuroradiol 2014 Nov-Dec;35(11):2192-6. Epub 2014 Jul 3 doi: 10.3174/ajnr.A4011. PMID: 24994821Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318

Diagnosis

Pleomorphic xanthoastrocytoma, anaplastic pleomorphic xanthoastrocytoma, and epithelioid glioblastoma: Case series with clinical characteristics, molecular features and progression relationship.
Lin Z, Yang R, Zheng H, Li Z, Yi G, Wu Q, Yang C, Huang G
Clin Neurol Neurosurg 2022 Oct;221:107379. Epub 2022 Jul 21 doi: 10.1016/j.clineuro.2022.107379. PMID: 35932588
Differentiation between supratentorial pilocytic astrocytoma and extraventricular ependymoma using multiparametric MRI.
Zhou X, Su Y, Huang W, Lin X, Xing Z, Cao D
Acta Radiol 2022 Dec;63(12):1661-1668. Epub 2021 Oct 28 doi: 10.1177/02841851211054195. PMID: 34709088
Supratentorial Tumors in Pediatric Patients.
Zamora C, Huisman TA, Izbudak I
Neuroimaging Clin N Am 2017 Feb;27(1):39-67. doi: 10.1016/j.nic.2016.08.003. PMID: 27889023
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article
Low-grade glial tumors: are they all the same?
Bristol RE
Semin Pediatr Neurol 2009 Mar;16(1):23-6. doi: 10.1016/j.spen.2009.03.002. PMID: 19410153

Therapy

Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial.
Todo T, Ito H, Ino Y, Ohtsu H, Ota Y, Shibahara J, Tanaka M
Nat Med 2022 Aug;28(8):1630-1639. Epub 2022 Jul 21 doi: 10.1038/s41591-022-01897-x. PMID: 35864254Free PMC Article
Stereotactic Cryodestruction of Gliomas.
Martynov BV, Kholyavin AI, Nizkovolos VB, Parfenov VE, Trufanov GE, Svistov DV
Prog Neurol Surg 2018;32:27-38. Epub 2018 Jul 10 doi: 10.1159/000469677. PMID: 29990971
Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318
Pediatric glial tumors.
Cohen KJ, Broniscer A, Glod J
Curr Treat Options Oncol 2001 Dec;2(6):529-36. doi: 10.1007/s11864-001-0074-9. PMID: 12057098

Prognosis

Clinical characteristics and prognosis of Glioblastoma patients with infratentorial recurrence.
Kawauchi D, Ohno M, Honda-Kitahara M, Miyakita Y, Takahashi M, Yanagisawa S, Tamura Y, Kikuchi M, Ichimura K, Narita Y
BMC Neurol 2023 Jan 7;23(1):9. doi: 10.1186/s12883-022-03047-9. PMID: 36609238Free PMC Article
Differentiation between supratentorial pilocytic astrocytoma and extraventricular ependymoma using multiparametric MRI.
Zhou X, Su Y, Huang W, Lin X, Xing Z, Cao D
Acta Radiol 2022 Dec;63(12):1661-1668. Epub 2021 Oct 28 doi: 10.1177/02841851211054195. PMID: 34709088
Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Aggressive behavior and anaplasia in pleomorphic xanthoastrocytoma: a plea for a revision of the current WHO classification.
Kahramancetin N, Tihan T
CNS Oncol 2013 Nov;2(6):523-30. doi: 10.2217/cns.13.56. PMID: 25054822Free PMC Article
Malignant gliomas in children.
Johnson JH Jr, Phillips PC
Cancer Invest 1996;14(6):609-21. doi: 10.3109/07357909609076905. PMID: 8951364

Clinical prediction guides

Clinical and Epidemiological Study of Intracranial Tumors in Children and Identification of Diagnostic Biomarkers for the Most Common Tumor Subtype and Their Relationship with the Immune Microenvironment Through Bioinformatics Analysis.
Wang G, Jia Y, Ye Y, Kang E, Chen H, Wang J, He X
J Mol Neurosci 2022 Jun;72(6):1208-1223. Epub 2022 Mar 28 doi: 10.1007/s12031-022-02003-z. PMID: 35347632
Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318
Aggressive behavior and anaplasia in pleomorphic xanthoastrocytoma: a plea for a revision of the current WHO classification.
Kahramancetin N, Tihan T
CNS Oncol 2013 Nov;2(6):523-30. doi: 10.2217/cns.13.56. PMID: 25054822Free PMC Article
Congenital brain tumors.
Raisanen JM, Davis RL
Pathology (Phila) 1993;2(1):103-16. PMID: 9420933

Recent systematic reviews

The role of radiation therapy in treatment of adults with newly diagnosed glioblastoma multiforme: a systematic review and evidence-based clinical practice guideline update.
Ziu M, Kim BYS, Jiang W, Ryken T, Olson JJ
J Neurooncol 2020 Nov;150(2):215-267. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03612-7. PMID: 33215344
Cytoreductive surgery in the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update.
Domino JS, Ormond DR, Germano IM, Sami M, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):121-142. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03606-5. PMID: 33215341
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article

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