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Neonatal Respiratory Distress Syndrome, AE

MedGen UID:: 1664440
•Concept ID:: C4724256
•: Finding

Synonym:

Neonatal Respiratory Distress Syndrome, Adverse Event

Definition

An adverse event in a newborn characterized by progressive alveolar atelectasis from birth due to an abnormality of synthesis, function or metabolism of surfactant, characterized by respiratory failure and an abnormal chest radiograph showing diffuse reticulogranular densities and air bronchograms. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNeonatal Respiratory Distress Syndrome, AE

Pathological Conditions, Signs and Symptoms
- Clinical finding
  - Finding by Cause
    - Adverse Event
      - Neonatal Adverse Event
        Neonatal Respiratory Distress Syndrome, AE
        Grade 1 Neonatal Respiratory Distress Syndrome, AE
        Grade 2 Neonatal Respiratory Distress Syndrome, AE
        Grade 3 Neonatal Respiratory Distress Syndrome, AE
        Grade 4 Neonatal Respiratory Distress Syndrome, AE
        Grade 5 Neonatal Respiratory Distress Syndrome, AE

Professional guidelines

PubMed

Interventions for the management of transient tachypnoea of the newborn - an overview of systematic reviews.

Bruschettini M, Hassan KO, Romantsik O, Banzi R, Calevo MG, Moresco L
Cochrane Database Syst Rev 2022 Feb 24;2(2):CD013563. doi: 10.1002/14651858.CD013563.pub2. PMID: 35199848 Free PMC Article

Update on ventilatory management of extremely preterm infants-A Neonatal Intensive Care Unit perspective.

Schulzke SM, Stoecklin B
Paediatr Anaesth 2022 Feb;32(2):363-371. Epub 2021 Dec 15 doi: 10.1111/pan.14369. PMID: 34878697 Free PMC Article

Evidence-based clinical guidelines on analgesia and sedation in newborn infants undergoing assisted ventilation and endotracheal intubation.

Ancora G, Lago P, Garetti E, Merazzi D, Savant Levet P, Bellieni CV, Pieragostini L, Pirelli A
Acta Paediatr 2019 Feb;108(2):208-217. Epub 2018 Dec 6 doi: 10.1111/apa.14606. PMID: 30290021

See all (167)

Recent clinical studies

Etiology

Update on ventilatory management of extremely preterm infants-A Neonatal Intensive Care Unit perspective.

Schulzke SM, Stoecklin B
Paediatr Anaesth 2022 Feb;32(2):363-371. Epub 2021 Dec 15 doi: 10.1111/pan.14369. PMID: 34878697 Free PMC Article

Antenatal corticosteroids prior to planned caesarean at term for improving neonatal outcomes.

Sotiriadis A, McGoldrick E, Makrydimas G, Papatheodorou S, Ioannidis JP, Stewart F, Parker R
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD006614. doi: 10.1002/14651858.CD006614.pub4. PMID: 34935127 Free PMC Article

Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome.

Abdel-Latif ME, Davis PG, Wheeler KI, De Paoli AG, Dargaville PA
Cochrane Database Syst Rev 2021 May 10;5(5):CD011672. doi: 10.1002/14651858.CD011672.pub2. PMID: 33970483 Free PMC Article

Continuous positive airway pressure (CPAP) for respiratory distress in preterm infants.

Ho JJ, Subramaniam P, Davis PG
Cochrane Database Syst Rev 2020 Oct 15;10(10):CD002271. doi: 10.1002/14651858.CD002271.pub3. PMID: 33058208 Free PMC Article

Neonatal respiratory distress syndrome: are risk factors the same in preterm and term infants?

Condò V, Cipriani S, Colnaghi M, Bellù R, Zanini R, Bulfoni C, Parazzini F, Mosca F
J Matern Fetal Neonatal Med 2017 Jun;30(11):1267-1272. Epub 2016 Aug 2 doi: 10.1080/14767058.2016.1210597. PMID: 27399933

See all (1471)

Diagnosis

Pneumothorax in a term newborn.

Jhaveri V, Vali P, Giusto E, Singh Y, Lakshminrusimha S
J Perinatol 2024 Apr;44(4):465-471. Epub 2024 Feb 26 doi: 10.1038/s41372-024-01899-2. PMID: 38409329

A randomized clinical trial of antibiotic treatment duration in preterm pre-labor rupture of membranes: 7 days vs until delivery.

Sung JH, Kim JH, Kim Y, Choi YS, Hong S, Choi SJ, Kim JS, Roh CR, Oh SY
Am J Obstet Gynecol MFM 2023 Apr;5(4):100886. Epub 2023 Feb 4 doi: 10.1016/j.ajogmf.2023.100886. PMID: 36746334

Randomized Trial of Surfactant Therapy via Laryngeal Mask Airway Versus Brief Tracheal Intubation in Neonates Born Preterm.

Gallup JA, Ndakor SM, Pezzano C, Pinheiro JMB
J Pediatr 2023 Mar;254:17-24.e2. Epub 2022 Oct 12 doi: 10.1016/j.jpeds.2022.10.009. PMID: 36241051

Antenatal corticosteroids prior to planned caesarean at term for improving neonatal outcomes.

Expiratory Flow Limitation During Mechanical Ventilation.

Junhasavasdikul D, Telias I, Grieco DL, Chen L, Gutierrez CM, Piraino T, Brochard L
Chest 2018 Oct;154(4):948-962. Epub 2018 Feb 9 doi: 10.1016/j.chest.2018.01.046. PMID: 29432712

See all (532)

Therapy

Update on ventilatory management of extremely preterm infants-A Neonatal Intensive Care Unit perspective.

Schulzke SM, Stoecklin B
Paediatr Anaesth 2022 Feb;32(2):363-371. Epub 2021 Dec 15 doi: 10.1111/pan.14369. PMID: 34878697 Free PMC Article

Antenatal corticosteroids prior to planned caesarean at term for improving neonatal outcomes.

Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome.

Abdel-Latif ME, Davis PG, Wheeler KI, De Paoli AG, Dargaville PA
Cochrane Database Syst Rev 2021 May 10;5(5):CD011672. doi: 10.1002/14651858.CD011672.pub2. PMID: 33970483 Free PMC Article

Continuous positive airway pressure (CPAP) for respiratory distress in preterm infants.

Ho JJ, Subramaniam P, Davis PG
Cochrane Database Syst Rev 2020 Oct 15;10(10):CD002271. doi: 10.1002/14651858.CD002271.pub3. PMID: 33058208 Free PMC Article

Neonatal respiratory distress syndrome: are risk factors the same in preterm and term infants?

See all (2500)

Prognosis

Different corticosteroids and regimens for accelerating fetal lung maturation for babies at risk of preterm birth.

Williams MJ, Ramson JA, Brownfoot FC
Cochrane Database Syst Rev 2022 Aug 9;8(8):CD006764. doi: 10.1002/14651858.CD006764.pub4. PMID: 35943347 Free PMC Article

Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.

McGoldrick E, Stewart F, Parker R, Dalziel SR
Cochrane Database Syst Rev 2020 Dec 25;12(12):CD004454. doi: 10.1002/14651858.CD004454.pub4. PMID: 33368142 Free PMC Article

Continuous positive airway pressure (CPAP) for respiratory distress in preterm infants.

Ho JJ, Subramaniam P, Davis PG
Cochrane Database Syst Rev 2020 Oct 15;10(10):CD002271. doi: 10.1002/14651858.CD002271.pub3. PMID: 33058208 Free PMC Article

Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.

Roberts D, Brown J, Medley N, Dalziel SR
Cochrane Database Syst Rev 2017 Mar 21;3(3):CD004454. doi: 10.1002/14651858.CD004454.pub3. PMID: 28321847 Free PMC Article

Neonatal respiratory distress syndrome: are risk factors the same in preterm and term infants?

See all (696)

Clinical prediction guides

Pneumothorax in a term newborn.

Jhaveri V, Vali P, Giusto E, Singh Y, Lakshminrusimha S
J Perinatol 2024 Apr;44(4):465-471. Epub 2024 Feb 26 doi: 10.1038/s41372-024-01899-2. PMID: 38409329

Evidence-based clinical guidelines on analgesia and sedation in newborn infants undergoing assisted ventilation and endotracheal intubation.

Ancora G, Lago P, Garetti E, Merazzi D, Savant Levet P, Bellieni CV, Pieragostini L, Pirelli A
Acta Paediatr 2019 Feb;108(2):208-217. Epub 2018 Dec 6 doi: 10.1111/apa.14606. PMID: 30290021

Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.

Roberts D, Brown J, Medley N, Dalziel SR
Cochrane Database Syst Rev 2017 Mar 21;3(3):CD004454. doi: 10.1002/14651858.CD004454.pub3. PMID: 28321847 Free PMC Article

Neonatal venlafaxine discontinuation syndrome: A mini-review.

Holland J, Brown R
Eur J Paediatr Neurol 2017 Mar;21(2):264-268. Epub 2016 Nov 25 doi: 10.1016/j.ejpn.2016.11.003. PMID: 27931774

Cesarean section.

Danforth DN
JAMA 1985 Feb 8;253(6):811-8. PMID: 3881613

See all (575)

Recent systematic reviews

Positioning for acute respiratory distress in hospitalised infants and children.

Bhandari AP, Nnate DA, Vasanthan L, Konstantinidis M, Thompson J
Cochrane Database Syst Rev 2022 Jun 6;6(6):CD003645. doi: 10.1002/14651858.CD003645.pub4. PMID: 35661343 Free PMC Article

Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.

McGoldrick E, Stewart F, Parker R, Dalziel SR
Cochrane Database Syst Rev 2020 Dec 25;12(12):CD004454. doi: 10.1002/14651858.CD004454.pub4. PMID: 33368142 Free PMC Article

Continuous positive airway pressure (CPAP) for respiratory distress in preterm infants.

Ho JJ, Subramaniam P, Davis PG
Cochrane Database Syst Rev 2020 Oct 15;10(10):CD002271. doi: 10.1002/14651858.CD002271.pub3. PMID: 33058208 Free PMC Article

Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data.

Romero R, Conde-Agudelo A, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Nicolaides KH
Am J Obstet Gynecol 2018 Feb;218(2):161-180. Epub 2017 Nov 17 doi: 10.1016/j.ajog.2017.11.576. PMID: 29157866 Free PMC Article

Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.

Roberts D, Brown J, Medley N, Dalziel SR
Cochrane Database Syst Rev 2017 Mar 21;3(3):CD004454. doi: 10.1002/14651858.CD004454.pub3. PMID: 28321847 Free PMC Article

See all (142)

MedGen

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Neonatal Respiratory Distress Syndrome, AE

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity