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Onychomatricoma

MedGen UID:
1667118
Concept ID:
C4751078
Neoplastic Process
Synonyms: nail matrix neoplasm; nail matrix tumor; nail matrix tumour; neoplasm of nail matrix; onychomatricoma; tumor of nail matrix; tumour of nail matrix
SNOMED CT: Onychomatricoma (773629001)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
Concept ID:
CN307042
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
 
Monarch Initiative: MONDO:0017587
Orphanet: ORPHA300512

Definition

A rare benign nail tumour originating in the nail matrix characterised by localised or diffuse thickening of the nail plate, increased transverse or longitudinal overcurvature, a yellow longitudinal band of variable width, swelling of the proximal nail fold, multiple splinter haemorrhages and the presence of honeycomb-like cavities in the distal margin of the nail plate. Nail dystrophy and dorsal pterygium may be associated. Occasionally a pigmented lesion has been reported. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOnychomatricoma

Professional guidelines

PubMed

Perrin C
Am J Dermatopathol 2024 May 1;46(5):328-329. Epub 2024 Feb 7 doi: 10.1097/DAD.0000000000002628. PMID: 38354374
Starace M, Rubin AI, Di Chiacchio NG, Pampaloni F, Alessandrini A, Piraccini BM, Iorizzo M
J Dtsch Dermatol Ges 2023 Feb;21(2):116-129. doi: 10.1111/ddg.14942. PMID: 36808456
Perrin C, Baran R, Pisani A, Ortonne JP, Michiels JF
Am J Dermatopathol 2002 Jun;24(3):199-203. doi: 10.1097/00000372-200206000-00002. PMID: 12140434

Recent clinical studies

Etiology

Perrin C, Ambrosetti D, Balme B, Thomas L
Am J Dermatopathol 2020 Nov;42(11):827-834. doi: 10.1097/DAD.0000000000001648. PMID: 32271204
Mundada P, Becker M, Lenoir V, Stefanelli S, Rougemont AL, Beaulieu JY, Boudabbous S
Eur J Radiol 2019 Mar;112:93-105. Epub 2019 Jan 6 doi: 10.1016/j.ejrad.2019.01.004. PMID: 30777226
Cinotti E, Veronesi G, Labeille B, Cambazard F, Piraccini BM, Dika E, Perrot JL, Rubegni P
J Eur Acad Dermatol Venereol 2018 Nov;32(11):1874-1878. Epub 2018 Jun 26 doi: 10.1111/jdv.15108. PMID: 29869357
Rushing CJ, Ivankiv R, Bullock NM, Rogers DE, Spinner SM
J Foot Ankle Surg 2017 Sep-Oct;56(5):1095-1098. Epub 2017 May 27 doi: 10.1053/j.jfas.2017.04.008. PMID: 28558997
Durrant MN, Palla BA, Binder SW
Foot Ankle Spec 2012 Feb;5(1):41-4. Epub 2011 Sep 30 doi: 10.1177/1938640011422593. PMID: 21965578

Diagnosis

Perrin C, Ambrosetti D
Acta Derm Venereol 2022 Jan 5;102:adv00628. doi: 10.2340/actadv.v101.546. PMID: 34694416Free PMC Article
Pessoa E Costa T, João AL, Pinheiro R, Carvalho R, Matos Pires E, Lencastre A
Am J Dermatopathol 2020 Feb;42(2):133-135. doi: 10.1097/DAD.0000000000001514. PMID: 31503009
Cinotti E, Veronesi G, Labeille B, Cambazard F, Piraccini BM, Dika E, Perrot JL, Rubegni P
J Eur Acad Dermatol Venereol 2018 Nov;32(11):1874-1878. Epub 2018 Jun 26 doi: 10.1111/jdv.15108. PMID: 29869357
Richert B, Lecerf P, Caucanas M, André J
Clin Dermatol 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014. PMID: 24079590
Haneke E, Fränken J
Dermatol Surg 1995 Nov;21(11):984-7. doi: 10.1111/j.1524-4725.1995.tb00538.x. PMID: 7582839

Prognosis

Perrin C, Ambrosetti D
Acta Derm Venereol 2022 Jan 5;102:adv00628. doi: 10.2340/actadv.v101.546. PMID: 34694416Free PMC Article
Gam D, Jaka A, Ferrándiz C
Indian J Dermatol Venereol Leprol 2019 Mar-Apr;85(2):190-191. doi: 10.4103/ijdvl.IJDVL_621_17. PMID: 30058567
Richert B, Lecerf P, Caucanas M, André J
Clin Dermatol 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014. PMID: 24079590
Sidhu HK, Patel RV, Goldenberg G
Dermatol Clin 2012 Oct;30(4):623-41, vi. Epub 2012 Aug 13 doi: 10.1016/j.det.2012.06.009. PMID: 23021050
Durrant MN, Palla BA, Binder SW
Foot Ankle Spec 2012 Feb;5(1):41-4. Epub 2011 Sep 30 doi: 10.1177/1938640011422593. PMID: 21965578

Clinical prediction guides

Liu Y, Zou D, Huang Q, Wang L
J Cutan Pathol 2023 Dec;50(12):1094-1098. Epub 2023 Aug 19 doi: 10.1111/cup.14514. PMID: 37596842
Perrin C
Am J Dermatopathol 2020 Feb;42(2):103-110. doi: 10.1097/DAD.0000000000001440. PMID: 31436573
Lesort C, Debarbieux S, Duru G, Dalle S, Poulhalon N, Thomas L
Dermatology 2015;231(2):177-83. Epub 2015 Jun 20 doi: 10.1159/000431315. PMID: 26111574
Wang L, Gao T, Wang G
J Cutan Pathol 2015 May;42(5):361-7. Epub 2015 Apr 6 doi: 10.1111/cup.12476. PMID: 25727336
Perrin C, Goettmann S, Baran R
J Am Acad Dermatol 1998 Oct;39(4 Pt 1):560-4. doi: 10.1016/s0190-9622(98)70004-0. PMID: 9777762

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