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Increased stool urobilinogen concentration

MedGen UID:
1670992
•Concept ID:
C4732886
•
Finding
HPO: HP:0500115

Definition

An increased amount of urobilinogen present in the stool. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased stool urobilinogen concentration

Recent clinical studies

Etiology

Intestinal colonization leading to fecal urobilinoid excretion may play a role in the pathogenesis of neonatal jaundice.
Vítek L, Kotal P, Jirsa M, Malina J, Cerná M, Chmelar D, Fevery J
J Pediatr Gastroenterol Nutr 2000 Mar;30(3):294-8. doi: 10.1097/00005176-200003000-00015. PMID: 10749414
Details of blood changes in 32 patients with pancytopenia associated with long-term exposure to benzene.
Aksoy M, Dinçol K, Erdem S, Akgün T, Dinçol G
Br J Ind Med 1972;29(1):56-64. doi: 10.1136/oem.29.1.56. PMID: 5060246Free PMC Article

Diagnosis

Quantitation of urobilinogen in feces, urine, bile and serum by direct spectrophotometry of zinc complex.
Kotal P, Fevery J
Clin Chim Acta 1991 Oct 14;202(1-2):1-9. doi: 10.1016/0009-8981(91)90250-g. PMID: 1807863

Therapy

Hemolysis during and after 21 days of head-down-tilt bed rest.
Trudel G, Uhthoff HK, Laneuville O
Physiol Rep 2017 Dec;5(24) doi: 10.14814/phy2.13469. PMID: 29263114Free PMC Article
Some aspects of bile acid and urobilinogen excretion and fecal elimination in men given a rural Guatemalan diet and egg formulas with and without added oat bran.
Kretsch MJ, Crawford L, Calloway DH
Am J Clin Nutr 1979 Jul;32(7):1492-6. doi: 10.1093/ajcn/32.7.1492. PMID: 453064
Details of blood changes in 32 patients with pancytopenia associated with long-term exposure to benzene.
Aksoy M, Dinçol K, Erdem S, Akgün T, Dinçol G
Br J Ind Med 1972;29(1):56-64. doi: 10.1136/oem.29.1.56. PMID: 5060246Free PMC Article

Clinical prediction guides

Hemolysis during and after 21 days of head-down-tilt bed rest.
Trudel G, Uhthoff HK, Laneuville O
Physiol Rep 2017 Dec;5(24) doi: 10.14814/phy2.13469. PMID: 29263114Free PMC Article
Intestinal colonization leading to fecal urobilinoid excretion may play a role in the pathogenesis of neonatal jaundice.
Vítek L, Kotal P, Jirsa M, Malina J, Cerná M, Chmelar D, Fevery J
J Pediatr Gastroenterol Nutr 2000 Mar;30(3):294-8. doi: 10.1097/00005176-200003000-00015. PMID: 10749414
Influence of antibiotics on the faecal excretion of bile pigments in healthy subjects.
Saxerholt H, Carlstedt-Duke B, Høverstad T, Lingaas E, Norin KE, Steinbakk M, Midtvedt T
Scand J Gastroenterol 1986 Oct;21(8):991-6. doi: 10.3109/00365528608996410. PMID: 3775264

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