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Positive blood barbiturate test

MedGen UID:
1670999
•Concept ID:
C4732887
•
Finding
HPO: HP:0500116

Definition

Detection of barbiturate metabolites such as Phenobarbital in blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPositive blood barbiturate test

Professional guidelines

PubMed

EMIT-st drug detection system for screening of barbiturates and benzodiazepines in serum.
Drost RH, Plomp TA, Maes RA
J Toxicol Clin Toxicol 1982 May;19(3):303-12. doi: 10.3109/15563658209025736. PMID: 6752436

Recent clinical studies

Etiology

Performance of an on-site urine multidrug test used by forensic physicians in determining the cause of death.
Bisch A, Ceelen M, Dorn T, Reijnders U, van den Hondel K, Stomp J, Burger JD, Franssen E
J Forensic Leg Med 2022 May;88:102346. Epub 2022 Apr 1 doi: 10.1016/j.jflm.2022.102346. PMID: 35417849
Involuntary patient length-of-stay at a suburban emergency department.
Maniaci MJ, Lachner C, Vadeboncoeur TF, Hodge DO, Dawson NL, Rummans TA, Roy A, Burton MC
Am J Emerg Med 2020 Mar;38(3):534-538. Epub 2019 May 24 doi: 10.1016/j.ajem.2019.05.045. PMID: 31153738
The prevalence of prenatal opioid and other drug use in Utah.
Buchi KF, Suarez C, Varner MW
Am J Perinatol 2013 Mar;30(3):241-4. Epub 2012 Aug 9 doi: 10.1055/s-0032-1323586. PMID: 22879357
Generalized allergic reactions during anesthesia.
Binkley K, Cheema A, Sussman G, Moudgil G, O'Connor M, Evans S, Dolovich J
J Allergy Clin Immunol 1992 Mar;89(3):768-74. doi: 10.1016/0091-6749(92)90386-g. PMID: 1545098
The dexamethasone suppression test: an overview of its current status in psychiatry. The APA Task Force on Laboratory Tests in Psychiatry.
Am J Psychiatry 1987 Oct;144(10):1253-62. doi: 10.1176/ajp.144.10.1253. PMID: 3310667

Diagnosis

Involuntary patient length-of-stay at a suburban emergency department.
Maniaci MJ, Lachner C, Vadeboncoeur TF, Hodge DO, Dawson NL, Rummans TA, Roy A, Burton MC
Am J Emerg Med 2020 Mar;38(3):534-538. Epub 2019 May 24 doi: 10.1016/j.ajem.2019.05.045. PMID: 31153738
Identification of phenobarbital and other barbiturates in forensic drug screening using positive electrospray ionization liquid chromatography-high resolution mass spectrometry.
Høj LJ, Mollerup CB, Rasmussen BS, Johansen SS, Linnet K, Dalsgaard PW
Drug Test Anal 2019 Aug;11(8):1258-1263. Epub 2019 May 24 doi: 10.1002/dta.2603. PMID: 30993867
Application of the Triage panel for drugs of abuse to forensic blood samples.
Moriya F, Hashimoto Y
Nihon Hoigaku Zasshi 1996 Apr;50(2):50-6. PMID: 8691649
Generalized allergic reactions during anesthesia.
Binkley K, Cheema A, Sussman G, Moudgil G, O'Connor M, Evans S, Dolovich J
J Allergy Clin Immunol 1992 Mar;89(3):768-74. doi: 10.1016/0091-6749(92)90386-g. PMID: 1545098
The dexamethasone suppression test: an overview of its current status in psychiatry. The APA Task Force on Laboratory Tests in Psychiatry.
Am J Psychiatry 1987 Oct;144(10):1253-62. doi: 10.1176/ajp.144.10.1253. PMID: 3310667

Therapy

Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury.
Koskinen LD, Sundström N, Hägglund L, Eklund A, Olivecrona M
Neurocrit Care 2019 Dec;31(3):494-500. doi: 10.1007/s12028-019-00741-4. PMID: 31123992Free PMC Article
Influence of Inflammation on the Pharmacokinetics of Perampanel.
Yamamoto Y, Takahashi Y, Horino A, Usui N, Nishida T, Imai K, Kagawa Y, Inoue Y
Ther Drug Monit 2018 Dec;40(6):725-729. doi: 10.1097/FTD.0000000000000556. PMID: 30086086
Free radicals and antioxidant enzymes in older adults after regular senior elastic band exercising: an experimental randomized controlled pilot study.
Liao LY, Chung WS, Chen KM
J Adv Nurs 2017 Jan;73(1):108-111. Epub 2016 Sep 16 doi: 10.1111/jan.13094. PMID: 27509593
Generalized allergic reactions during anesthesia.
Binkley K, Cheema A, Sussman G, Moudgil G, O'Connor M, Evans S, Dolovich J
J Allergy Clin Immunol 1992 Mar;89(3):768-74. doi: 10.1016/0091-6749(92)90386-g. PMID: 1545098
Alcohol and secobarbital effects as a function of familial alcoholism: extended intoxication and increased withdrawal effects.
McCaul ME, Turkkan JS, Svikis DS, Bigelow GE
Alcohol Clin Exp Res 1991 Feb;15(1):94-101. doi: 10.1111/j.1530-0277.1991.tb00524.x. PMID: 2024739

Prognosis

Performance of an on-site urine multidrug test used by forensic physicians in determining the cause of death.
Bisch A, Ceelen M, Dorn T, Reijnders U, van den Hondel K, Stomp J, Burger JD, Franssen E
J Forensic Leg Med 2022 May;88:102346. Epub 2022 Apr 1 doi: 10.1016/j.jflm.2022.102346. PMID: 35417849
Neuroprotective role of neurophysiological monitoring during endovascular procedures in the brain and spinal cord.
Sala F, Beltramello A, Gerosa M
Neurophysiol Clin 2007 Dec;37(6):415-21. Epub 2007 Nov 9 doi: 10.1016/j.neucli.2007.10.004. PMID: 18083497
Epidemiology of alcohol and other drug use among motor vehicle crash victims admitted to a trauma center.
Walsh JM, Flegel R, Cangianelli LA, Atkins R, Soderstrom CA, Kerns TJ
Traffic Inj Prev 2004 Sep;5(3):254-60. doi: 10.1080/15389580490465319. PMID: 15276926
Substance abuse in victims of fire.
Barillo DJ, Goode R
J Burn Care Rehabil 1996 Jan-Feb;17(1):71-6. doi: 10.1097/00004630-199601000-00014. PMID: 8808362
Effect of chronic substance abuse on the neuropsychological performance of intravenous drug users with a high prevalence of HIV-1 seropositivity.
Concha M, Graham NM, Muñoz A, Vlahov D, Royal W 3rd, Updike M, Nance-Sproson T, Selnes OA, McArthur JC
Am J Epidemiol 1992 Dec 1;136(11):1338-48. doi: 10.1093/oxfordjournals.aje.a116446. PMID: 1362630

Clinical prediction guides

Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury.
Koskinen LD, Sundström N, Hägglund L, Eklund A, Olivecrona M
Neurocrit Care 2019 Dec;31(3):494-500. doi: 10.1007/s12028-019-00741-4. PMID: 31123992Free PMC Article
Identification of phenobarbital and other barbiturates in forensic drug screening using positive electrospray ionization liquid chromatography-high resolution mass spectrometry.
Høj LJ, Mollerup CB, Rasmussen BS, Johansen SS, Linnet K, Dalsgaard PW
Drug Test Anal 2019 Aug;11(8):1258-1263. Epub 2019 May 24 doi: 10.1002/dta.2603. PMID: 30993867
Comparison of nonradioactive microtiter plate enzyme immunoassays for the sensitive detection of fentanyl.
Käferstein H, Sticht G
Forensic Sci Int 2000 Sep 11;113(1-3):353-7. doi: 10.1016/s0379-0738(00)00224-3. PMID: 10978648
Application of the Triage panel for drugs of abuse to forensic blood samples.
Moriya F, Hashimoto Y
Nihon Hoigaku Zasshi 1996 Apr;50(2):50-6. PMID: 8691649
A comparative study on the clinical effects of rectal diazepam and pentobarbital on small children. Relationship between plasma level and effect.
Kanto J, Iisalo E, Kangas L, Valovirta E
Int J Clin Pharmacol Ther Toxicol 1980;18(8):348-51. PMID: 7409937

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