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Positive urine cocaine test

MedGen UID:
1671099
•Concept ID:
C4732879
•
Finding
HPO: HP:0500108

Definition

Detection of cocaine or its major metabolite, benzoylecgonine, in urine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPositive urine cocaine test

Professional guidelines

PubMed

β-Blocker treatment and prognosis in acute coronary syndrome associated with cocaine consumption: The RUTI-Cocaine Study.
Cediel G, Carrillo X, García-García C, Rueda F, Oliveras T, Labata C, Serra J, Ferrer M, de Diego O, Bayés-Genís A
Int J Cardiol 2018 Jun 1;260:7-10. doi: 10.1016/j.ijcard.2018.02.013. PMID: 29622456

Recent clinical studies

Etiology

Urine Drug Test Results Among Adolescents and Young Adults in an Outpatient Office-Based Opioid Treatment Program.
Ramey OL, Bonny AE, Silva Almodóvar A, Nahata MC
J Adolesc Health 2023 Jul;73(1):141-147. Epub 2023 Apr 6 doi: 10.1016/j.jadohealth.2023.02.013. PMID: 37031090
A Positive Cocaine Urine Toxicology Test and the Effect on Intraoperative Hemodynamics Under General Anesthesia.
Moon TS, Pak TJ, Kim A, Gonzales MX, Volnov Y, Wright E, Vu KQ, Lu RD, Sharifi A, Minhajuddin A, Chen JL, Fox PE, Gasanova I, Fox AA, Stewart J, Ogunnaike B
Anesth Analg 2021 Feb 1;132(2):308-316. doi: 10.1213/ANE.0000000000004808. PMID: 32304462
Carvedilol does not reduce cocaine use in methadone-maintained cocaine users.
Sofuoglu M, Poling J, Babuscio T, Gonsai K, Severino K, Nich C, Carroll KM
J Subst Abuse Treat 2017 Feb;73:63-69. Epub 2016 Nov 17 doi: 10.1016/j.jsat.2016.11.005. PMID: 28017186Free PMC Article
WITHDRAWN: Antidepressants for cocaine dependence.
Silva de Lima M, Farrell M, Lima Reisser AA, Soares B
Cochrane Database Syst Rev 2010 Feb 17;(2):CD002950. doi: 10.1002/14651858.CD002950.pub2. PMID: 20166064
Antidepressants for cocaine dependence.
Lima MS, Reisser AA, Soares BG, Farrell M
Cochrane Database Syst Rev 2001;(4):CD002950. doi: 10.1002/14651858.CD002950. PMID: 11687168

Diagnosis

Urine Drug Test Results Among Adolescents and Young Adults in an Outpatient Office-Based Opioid Treatment Program.
Ramey OL, Bonny AE, Silva Almodóvar A, Nahata MC
J Adolesc Health 2023 Jul;73(1):141-147. Epub 2023 Apr 6 doi: 10.1016/j.jadohealth.2023.02.013. PMID: 37031090
A Positive Cocaine Urine Toxicology Test and the Effect on Intraoperative Hemodynamics Under General Anesthesia.
Moon TS, Pak TJ, Kim A, Gonzales MX, Volnov Y, Wright E, Vu KQ, Lu RD, Sharifi A, Minhajuddin A, Chen JL, Fox PE, Gasanova I, Fox AA, Stewart J, Ogunnaike B
Anesth Analg 2021 Feb 1;132(2):308-316. doi: 10.1213/ANE.0000000000004808. PMID: 32304462
Clinical Benefits of Direct-to-Definitive Testing for Monitoring Compliance in Pain Management.
Gencheva R, Petrides A, Kantartjis M, Tanasijevic M, Dahlin JL, Melanson S
Pain Physician 2018 Nov;21(6):E583-E592. PMID: 30508989
WITHDRAWN: Antidepressants for cocaine dependence.
Silva de Lima M, Farrell M, Lima Reisser AA, Soares B
Cochrane Database Syst Rev 2010 Feb 17;(2):CD002950. doi: 10.1002/14651858.CD002950.pub2. PMID: 20166064
Antidepressants for cocaine dependence.
Lima MS, Reisser AA, Soares BG, Farrell M
Cochrane Database Syst Rev 2001;(4):CD002950. doi: 10.1002/14651858.CD002950. PMID: 11687168

Therapy

Urine Drug Test Results Among Adolescents and Young Adults in an Outpatient Office-Based Opioid Treatment Program.
Ramey OL, Bonny AE, Silva Almodóvar A, Nahata MC
J Adolesc Health 2023 Jul;73(1):141-147. Epub 2023 Apr 6 doi: 10.1016/j.jadohealth.2023.02.013. PMID: 37031090
A Positive Cocaine Urine Toxicology Test and the Effect on Intraoperative Hemodynamics Under General Anesthesia.
Moon TS, Pak TJ, Kim A, Gonzales MX, Volnov Y, Wright E, Vu KQ, Lu RD, Sharifi A, Minhajuddin A, Chen JL, Fox PE, Gasanova I, Fox AA, Stewart J, Ogunnaike B
Anesth Analg 2021 Feb 1;132(2):308-316. doi: 10.1213/ANE.0000000000004808. PMID: 32304462
Carvedilol does not reduce cocaine use in methadone-maintained cocaine users.
Sofuoglu M, Poling J, Babuscio T, Gonsai K, Severino K, Nich C, Carroll KM
J Subst Abuse Treat 2017 Feb;73:63-69. Epub 2016 Nov 17 doi: 10.1016/j.jsat.2016.11.005. PMID: 28017186Free PMC Article
Trojan horses: drug culprits associated with antineutrophil cytoplasmic autoantibody (ANCA) vasculitis.
Pendergraft WF 3rd, Niles JL
Curr Opin Rheumatol 2014 Jan;26(1):42-9. doi: 10.1097/BOR.0000000000000014. PMID: 24276086
WITHDRAWN: Antidepressants for cocaine dependence.
Silva de Lima M, Farrell M, Lima Reisser AA, Soares B
Cochrane Database Syst Rev 2010 Feb 17;(2):CD002950. doi: 10.1002/14651858.CD002950.pub2. PMID: 20166064

Prognosis

Non-prescription Fentanyl Positive Toxicology: Prevalence, Positive Predictive Value of Fentanyl Immunoassay Screening, and Description of Co-substance Use.
Kerensky T, LaRochelle M, Fan SL, Kosakowski S, Wason K, Walley AY
J Addict Med 2021 Apr 1;15(2):150-154. doi: 10.1097/ADM.0000000000000723. PMID: 32909981
A Positive Cocaine Urine Toxicology Test and the Effect on Intraoperative Hemodynamics Under General Anesthesia.
Moon TS, Pak TJ, Kim A, Gonzales MX, Volnov Y, Wright E, Vu KQ, Lu RD, Sharifi A, Minhajuddin A, Chen JL, Fox PE, Gasanova I, Fox AA, Stewart J, Ogunnaike B
Anesth Analg 2021 Feb 1;132(2):308-316. doi: 10.1213/ANE.0000000000004808. PMID: 32304462
Rate of Fentanyl Positivity Among Urine Drug Test Results Positive for Cocaine or Methamphetamine.
LaRue L, Twillman RK, Dawson E, Whitley P, Frasco MA, Huskey A, Guevara MG
JAMA Netw Open 2019 Apr 5;2(4):e192851. doi: 10.1001/jamanetworkopen.2019.2851. PMID: 31026029Free PMC Article
Carvedilol does not reduce cocaine use in methadone-maintained cocaine users.
Sofuoglu M, Poling J, Babuscio T, Gonsai K, Severino K, Nich C, Carroll KM
J Subst Abuse Treat 2017 Feb;73:63-69. Epub 2016 Nov 17 doi: 10.1016/j.jsat.2016.11.005. PMID: 28017186Free PMC Article
Effect of buprenorphine dose on treatment outcome.
Fareed A, Vayalapalli S, Casarella J, Drexler K
J Addict Dis 2012;31(1):8-18. doi: 10.1080/10550887.2011.642758. PMID: 22356665

Clinical prediction guides

Clinical and Functional Connectivity Outcomes of 5-Hz Repetitive Transcranial Magnetic Stimulation as an Add-on Treatment in Cocaine Use Disorder: A Double-Blind Randomized Controlled Trial.
Garza-Villarreal EA, Alcala-Lozano R, Fernandez-Lozano S, Morelos-Santana E, Dávalos A, Villicaña V, Alcauter S, Castellanos FX, Gonzalez-Olvera JJ
Biol Psychiatry Cogn Neurosci Neuroimaging 2021 Jul;6(7):745-757. Epub 2021 Jan 26 doi: 10.1016/j.bpsc.2021.01.003. PMID: 33508499
A Positive Cocaine Urine Toxicology Test and the Effect on Intraoperative Hemodynamics Under General Anesthesia.
Moon TS, Pak TJ, Kim A, Gonzales MX, Volnov Y, Wright E, Vu KQ, Lu RD, Sharifi A, Minhajuddin A, Chen JL, Fox PE, Gasanova I, Fox AA, Stewart J, Ogunnaike B
Anesth Analg 2021 Feb 1;132(2):308-316. doi: 10.1213/ANE.0000000000004808. PMID: 32304462
Rate of Fentanyl Positivity Among Urine Drug Test Results Positive for Cocaine or Methamphetamine.
LaRue L, Twillman RK, Dawson E, Whitley P, Frasco MA, Huskey A, Guevara MG
JAMA Netw Open 2019 Apr 5;2(4):e192851. doi: 10.1001/jamanetworkopen.2019.2851. PMID: 31026029Free PMC Article
Carvedilol does not reduce cocaine use in methadone-maintained cocaine users.
Sofuoglu M, Poling J, Babuscio T, Gonsai K, Severino K, Nich C, Carroll KM
J Subst Abuse Treat 2017 Feb;73:63-69. Epub 2016 Nov 17 doi: 10.1016/j.jsat.2016.11.005. PMID: 28017186Free PMC Article
Effect of buprenorphine dose on treatment outcome.
Fareed A, Vayalapalli S, Casarella J, Drexler K
J Addict Dis 2012;31(1):8-18. doi: 10.1080/10550887.2011.642758. PMID: 22356665

Recent systematic reviews

WITHDRAWN: Antidepressants for cocaine dependence.
Silva de Lima M, Farrell M, Lima Reisser AA, Soares B
Cochrane Database Syst Rev 2010 Feb 17;(2):CD002950. doi: 10.1002/14651858.CD002950.pub2. PMID: 20166064
Antidepressants for cocaine dependence.
Lima MS, Reisser AA, Soares BG, Farrell M
Cochrane Database Syst Rev 2003;(2):CD002950. doi: 10.1002/14651858.CD002950. PMID: 12804445
Antidepressants for cocaine dependence.
Lima MS, Reisser AA, Soares BG, Farrell M
Cochrane Database Syst Rev 2001;(4):CD002950. doi: 10.1002/14651858.CD002950. PMID: 11687168

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