Pituitary dermoid and epidermoid cysts

MedGen UID:: 1674582
•Concept ID:: C5190781
•: Neoplastic Process

Synonym:	pituitary dermoid and epidermoid cysts
SNOMED CT:	Pituitary dermoid and epidermoid cysts (783008000)

Monarch Initiative:	MONDO:0019615
Orphanet:	ORPHA91351

Definition

A rare acquired pituitary hormone deficiency characterised by the presence of rare benign tumour in the sellar region. Clinical presentation is either acute or insidious and is variable according to the cyst location, size and potential rupture. Most commonly patients present with headache, visual disturbances and pituitary dysfunction. [from SNOMEDCT_US]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPituitary dermoid and epidermoid cysts

Pathological process
- Disease
  - Disorder by Site
    - Disorder of endocrine system
      - Disorder of adrenal gland
        Neoplasm of the adrenal gland
        Pituitary dermoid and epidermoid cysts

Recent clinical studies

Etiology

Endoscopically operated 15 ventral skull-base dermoid and epidermoid cysts: Outcomes of a case series and technical note.

Ergen A, Caklili M, Uzuner A, Kurnaz Ozbek S, Cabuk B, Anik I, Ceylan S
Neurochirurgie 2023 Mar;69(2):101424. Epub 2023 Mar 1 doi: 10.1016/j.neuchi.2023.101424. PMID: 36868134

The Expanding Spectrum of Disease Treated by the Transnasal, Transsphenoidal Microscopic and Endoscopic Anterior Skull Base Approach: A Single-Center Experience 2008-2015.

Cote DJ, Wiemann R, Smith TR, Dunn IF, Al-Mefty O, Laws ER
World Neurosurg 2015 Oct;84(4):899-905. Epub 2015 May 22 doi: 10.1016/j.wneu.2015.05.019. PMID: 26008142

Endoscopic endonasal skull base surgery in the pediatric population.

Chivukula S, Koutourousiou M, Snyderman CH, Fernandez-Miranda JC, Gardner PA, Tyler-Kabara EC
J Neurosurg Pediatr 2013 Mar;11(3):227-41. Epub 2012 Dec 14 doi: 10.3171/2012.10.PEDS12160. PMID: 23240846

Epithelial cystic lesions of the sellar and parasellar region: a continuum of ectodermal derivatives?

Harrison MJ, Morgello S, Post KD
J Neurosurg 1994 Jun;80(6):1018-25. doi: 10.3171/jns.1994.80.6.1018. PMID: 8189257

Distribution of cellular carbohydrate moieties in human dysontogenetic brain tumors, especially in craniopharyngioma and epidermoid/dermoid.

Niikawa S, Yamada H, Sakai N, Ando T, Zhang W, Hara A, Shimokawa K
Acta Neuropathol 1992;85(1):71-8. doi: 10.1007/BF00304635. PMID: 1337421

See all (5)

Diagnosis

Intrasellar Dermoid Cyst: Case Report of a Rare Lesion and Systematic Literature Review Comparing Intrasellar, Suprasellar, and Parasellar Locations.

Donofrio CA, Bertazzoni G, Riccio L, Pinacoli A, Pianta L, Generali D, Ungari M, Servadei F, Roncaroli F, Fioravanti A
World Neurosurg 2024 Feb;182:83-90. Epub 2023 Nov 22 doi: 10.1016/j.wneu.2023.11.057. PMID: 37995988

The Expanding Spectrum of Disease Treated by the Transnasal, Transsphenoidal Microscopic and Endoscopic Anterior Skull Base Approach: A Single-Center Experience 2008-2015.

Cote DJ, Wiemann R, Smith TR, Dunn IF, Al-Mefty O, Laws ER
World Neurosurg 2015 Oct;84(4):899-905. Epub 2015 May 22 doi: 10.1016/j.wneu.2015.05.019. PMID: 26008142

Craniopharyngioma: a pathologic, clinical, and surgical review.

Fernandez-Miranda JC, Gardner PA, Snyderman CH, Devaney KO, Strojan P, Suárez C, Genden EM, Rinaldo A, Ferlito A
Head Neck 2012 Jul;34(7):1036-44. Epub 2011 May 16 doi: 10.1002/hed.21771. PMID: 21584897

Craniopharyngioma and other cystic epithelial lesions of the sellar region: a review of clinical, imaging, and histopathological relationships.

Zada G, Lin N, Ojerholm E, Ramkissoon S, Laws ER
Neurosurg Focus 2010 Apr;28(4):E4. doi: 10.3171/2010.2.FOCUS09318. PMID: 20367361

Epithelial cystic lesions of the sellar and parasellar region: a continuum of ectodermal derivatives?

Harrison MJ, Morgello S, Post KD
J Neurosurg 1994 Jun;80(6):1018-25. doi: 10.3171/jns.1994.80.6.1018. PMID: 8189257

See all (5)

Therapy

Endoscopic endonasal skull base surgery in the pediatric population.

See all (1)

Prognosis

Intraoperative Navigated Angiosonography for Skull Base Tumor Surgery.

Prada F, Del Bene M, Casali C, Saladino A, Legnani FG, Perin A, Moiraghi A, Richetta C, Rampini A, Mattei L, Vetrano IG, Fornaro R, Saini M, Martegani A, DiMeco F
World Neurosurg 2015 Dec;84(6):1699-707. Epub 2015 Jul 17 doi: 10.1016/j.wneu.2015.07.025. PMID: 26193670

Epithelial cystic lesions of the sellar and parasellar region: a continuum of ectodermal derivatives?

Harrison MJ, Morgello S, Post KD
J Neurosurg 1994 Jun;80(6):1018-25. doi: 10.3171/jns.1994.80.6.1018. PMID: 8189257

See all (2)