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Enteropathogenic E coli Infection

MedGen UID:
1675034
•Concept ID:
C4763882
•
Disease or Syndrome

Definition

A pathotype of Escherichia coli, which is a gram-negative bacteria that is transmitted through the fecal-oral route. It has an incubation period of 9-12 hours and a duration of 12 days. Symptoms may include persistent severe acute diarrhea. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnteropathogenic E coli Infection

Recent clinical studies

Etiology

Cluster investigation of mixed O76:H19 Shiga toxin-producing Escherichia coli and atypical enteropathogenic E. coli infection in a Spanish household.
Sánchez S, Cenoz MG, Martín C, Beristain X, Llorente MT, Herrera-León S
Epidemiol Infect 2014 May;142(5):1029-33. Epub 2013 Aug 2 doi: 10.1017/S0950268813001842. PMID: 23906309Free PMC Article
Human colostrum contains IgA antibodies reactive to enteropathogenic Escherichia coli virulence-associated proteins: intimin, BfpA, EspA, and EspB.
Loureiro I, Frankel G, Adu-Bobie J, Dougan G, Trabulsi LR, Carneiro-Sampaio MM
J Pediatr Gastroenterol Nutr 1998 Aug;27(2):166-71. doi: 10.1097/00005176-199808000-00007. PMID: 9702647
Use of human colostrum in the management of chronic infantile diarrhoea due to enteropathogenic E. coli infection with associated intestinal parasite infestations and undernutrition.
Saha K, Dua N, Chopra K
J Trop Pediatr 1990 Oct;36(5):247-50. doi: 10.1093/tropej/36.5.247. PMID: 2126564

Diagnosis

Dietary phytate primes epithelial antibacterial immunity in the intestine.
Hashimoto-Hill S, Colapietro L, Woo V, Antonacci S, Whitt J, Engleman L, Alenghat T
Front Immunol 2022;13:952994. Epub 2022 Oct 19 doi: 10.3389/fimmu.2022.952994. PMID: 36341403Free PMC Article
Epithelial cell proliferation in childhood enteropathies.
Savidge TC, Shmakov AN, Walker-Smith JA, Phillips AD
Gut 1996 Aug;39(2):185-93. doi: 10.1136/gut.39.2.185. PMID: 8977336Free PMC Article
Laboratory diagnosis of foodborne diseases.
Kazal HL
Ann Clin Lab Sci 1976 Sep-Oct;6(5):381-99. PMID: 184732

Prognosis

Diarrheagenic Escherichia coli in acute gastroenteritis in infants in North-West Italy.
Amisano G, Fornasero S, Migliaretti G, Caramello S, Tarasco V, Savino F
New Microbiol 2011 Jan;34(1):45-51. Epub 2011 Jan 15 PMID: 21344146

Clinical prediction guides

Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ.
Zhang Y, Mühlen S, Oates CV, Pearson JS, Hartland EL
J Biol Chem 2016 Sep 16;291(38):20149-62. Epub 2016 Jul 21 doi: 10.1074/jbc.M116.734079. PMID: 27445336Free PMC Article

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