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Enterotoxigenic E coli Infection

MedGen UID:
1681359
•Concept ID:
C4763883
•
Disease or Syndrome

Definition

A pathotype of Escherichia coli, which is a gram-negative bacteria that is transmitted through the fecal-oral route. It has an incubation period of 10-72 hours and a duration of 1-5 days. Symptoms may include acute, occasionally severe diarrhea without fever. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnterotoxigenic E coli Infection

Professional guidelines

PubMed

Intestinal bacteria and colorectal cancer: etiology and treatment.
Dougherty MW, Jobin C
Gut Microbes 2023 Jan-Dec;15(1):2185028. doi: 10.1080/19490976.2023.2185028. PMID: 36927206Free PMC Article
Enterotoxigenic Escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and prevention.
Qadri F, Svennerholm AM, Faruque AS, Sack RB
Clin Microbiol Rev 2005 Jul;18(3):465-83. doi: 10.1128/CMR.18.3.465-483.2005. PMID: 16020685Free PMC Article
Prevention and treatment of traveler's diarrhea.
Juckett G
Am Fam Physician 1999 Jul;60(1):119-24, 135-6. PMID: 10414633

Recent clinical studies

Etiology

Feasibility of Polyclonal Avian Immunoglobulins (IgY) as Prophylaxis against Human Norovirus Infection.
Artman C, Idegwu N, Brumfield KD, Lai K, Hauta S, Falzarano D, Parreño V, Yuan L, Geyer JD, Goepp JG
Viruses 2022 Oct 27;14(11) doi: 10.3390/v14112371. PMID: 36366469Free PMC Article
Correlation of Clinical Outcomes With Multiplex Molecular Testing of Stool From Children Admitted to Hospital With Gastroenteritis in Botswana.
Pernica JM, Steenhoff AP, Welch H, Mokomane M, Quaye I, Arscott-Mills T, Mazhani L, Lechiile K, Mahony J, Smieja M, Goldfarb DM
J Pediatric Infect Dis Soc 2016 Sep;5(3):312-8. Epub 2015 May 16 doi: 10.1093/jpids/piv028. PMID: 26407262Free PMC Article
Contamination level and ingestion dose of foodborne pathogens associated with infections.
Hara-Kudo Y, Takatori K
Epidemiol Infect 2011 Oct;139(10):1505-10. Epub 2010 Dec 23 doi: 10.1017/S095026881000292X. PMID: 21205441

Diagnosis

Large-scale evaluation of a rapid diagnostic test for diarrhea caused by enterotoxigenic Escherichia coli targeting the heat-labile toxin.
Henrique C, Caetano BA, Mitsunari T, Dos Santos LF, Piazza RMF, Rocha LB
J Microbiol Methods 2018 Jan;144:125-127. Epub 2017 Nov 23 doi: 10.1016/j.mimet.2017.11.020. PMID: 29175533
Correlation of Clinical Outcomes With Multiplex Molecular Testing of Stool From Children Admitted to Hospital With Gastroenteritis in Botswana.
Pernica JM, Steenhoff AP, Welch H, Mokomane M, Quaye I, Arscott-Mills T, Mazhani L, Lechiile K, Mahony J, Smieja M, Goldfarb DM
J Pediatric Infect Dis Soc 2016 Sep;5(3):312-8. Epub 2015 May 16 doi: 10.1093/jpids/piv028. PMID: 26407262Free PMC Article
A rapid test for infectious and inflammatory enteritis.
Miller JR, Barrett LJ, Kotloff K, Guerrant RL
Arch Intern Med 1994 Dec 12-26;154(23):2660-4. doi: 10.1001/archinte.1994.00420230043006. PMID: 7993149

Therapy

Correlation of Clinical Outcomes With Multiplex Molecular Testing of Stool From Children Admitted to Hospital With Gastroenteritis in Botswana.
Pernica JM, Steenhoff AP, Welch H, Mokomane M, Quaye I, Arscott-Mills T, Mazhani L, Lechiile K, Mahony J, Smieja M, Goldfarb DM
J Pediatric Infect Dis Soc 2016 Sep;5(3):312-8. Epub 2015 May 16 doi: 10.1093/jpids/piv028. PMID: 26407262Free PMC Article
Plant-based vaccines against diarrheal diseases.
Tacket CO
Trans Am Clin Climatol Assoc 2007;118:79-87. PMID: 18528491Free PMC Article
A double-blind, controlled trial of bioflorin (Streptococcus faecium SF68) in adults with acute diarrhea due to Vibrio cholerae and enterotoxigenic Escherichia coli.
Mitra AK, Rabbani GH
Gastroenterology 1990 Oct;99(4):1149-52. doi: 10.1016/0016-5085(90)90638-h. PMID: 2203662

Prognosis

Correlation of Clinical Outcomes With Multiplex Molecular Testing of Stool From Children Admitted to Hospital With Gastroenteritis in Botswana.
Pernica JM, Steenhoff AP, Welch H, Mokomane M, Quaye I, Arscott-Mills T, Mazhani L, Lechiile K, Mahony J, Smieja M, Goldfarb DM
J Pediatric Infect Dis Soc 2016 Sep;5(3):312-8. Epub 2015 May 16 doi: 10.1093/jpids/piv028. PMID: 26407262Free PMC Article
A rapid test for infectious and inflammatory enteritis.
Miller JR, Barrett LJ, Kotloff K, Guerrant RL
Arch Intern Med 1994 Dec 12-26;154(23):2660-4. doi: 10.1001/archinte.1994.00420230043006. PMID: 7993149

Clinical prediction guides

Phylogenetic comparisons reveal multiple acquisitions of the toxin genes by enterotoxigenic Escherichia coli strains of different evolutionary lineages.
Turner SM, Chaudhuri RR, Jiang ZD, DuPont H, Gyles C, Penn CW, Pallen MJ, Henderson IR
J Clin Microbiol 2006 Dec;44(12):4528-36. Epub 2006 Oct 18 doi: 10.1128/JCM.01474-06. PMID: 17050815Free PMC Article
A rapid test for infectious and inflammatory enteritis.
Miller JR, Barrett LJ, Kotloff K, Guerrant RL
Arch Intern Med 1994 Dec 12-26;154(23):2660-4. doi: 10.1001/archinte.1994.00420230043006. PMID: 7993149

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