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HHV8-Positive Multicentric Castleman Disease

MedGen UID:
1683931
•Concept ID:
C5197664
•
Disease or Syndrome
Synonyms: HHV-8-Associated Multicentric Castleman Disease; HHV8 Multicentric Castleman Disease; KSHV Muticentric Castleman Disease; KSHV-Associated Multicentric Castleman Disease

Definition

A systemic form of angiofollicular hyperplasia associated with HHV8 infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHHV8-Positive Multicentric Castleman Disease

Professional guidelines

PubMed

Diagnosis and Management of Castleman Disease.
Abramson JS
J Natl Compr Canc Netw 2019 Nov;17(11.5):1417-1419. doi: 10.6004/jnccn.2019.5037. PMID: 31766018

Recent clinical studies

Etiology

Demographic characteristics and prognosis of HHV8-positive diffuse large B-cell lymphoma, not otherwise specified: Insights from a population-based study with a 10-year follow-up.
Wang F, Du Z
Medicine (Baltimore) 2023 Dec 15;102(50):e36464. doi: 10.1097/MD.0000000000036464. PMID: 38115350Free PMC Article
Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients.
Pria AD, Pinato D, Roe J, Naresh K, Nelson M, Bower M
Blood 2017 Apr 13;129(15):2143-2147. Epub 2017 Jan 31 doi: 10.1182/blood-2016-10-747477. PMID: 28143881

Diagnosis

Demographic characteristics and prognosis of HHV8-positive diffuse large B-cell lymphoma, not otherwise specified: Insights from a population-based study with a 10-year follow-up.
Wang F, Du Z
Medicine (Baltimore) 2023 Dec 15;102(50):e36464. doi: 10.1097/MD.0000000000036464. PMID: 38115350Free PMC Article
Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients.
Pria AD, Pinato D, Roe J, Naresh K, Nelson M, Bower M
Blood 2017 Apr 13;129(15):2143-2147. Epub 2017 Jan 31 doi: 10.1182/blood-2016-10-747477. PMID: 28143881

Therapy

Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients.
Pria AD, Pinato D, Roe J, Naresh K, Nelson M, Bower M
Blood 2017 Apr 13;129(15):2143-2147. Epub 2017 Jan 31 doi: 10.1182/blood-2016-10-747477. PMID: 28143881

Prognosis

Demographic characteristics and prognosis of HHV8-positive diffuse large B-cell lymphoma, not otherwise specified: Insights from a population-based study with a 10-year follow-up.
Wang F, Du Z
Medicine (Baltimore) 2023 Dec 15;102(50):e36464. doi: 10.1097/MD.0000000000036464. PMID: 38115350Free PMC Article
Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients.
Pria AD, Pinato D, Roe J, Naresh K, Nelson M, Bower M
Blood 2017 Apr 13;129(15):2143-2147. Epub 2017 Jan 31 doi: 10.1182/blood-2016-10-747477. PMID: 28143881

Clinical prediction guides

Demographic characteristics and prognosis of HHV8-positive diffuse large B-cell lymphoma, not otherwise specified: Insights from a population-based study with a 10-year follow-up.
Wang F, Du Z
Medicine (Baltimore) 2023 Dec 15;102(50):e36464. doi: 10.1097/MD.0000000000036464. PMID: 38115350Free PMC Article
Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients.
Pria AD, Pinato D, Roe J, Naresh K, Nelson M, Bower M
Blood 2017 Apr 13;129(15):2143-2147. Epub 2017 Jan 31 doi: 10.1182/blood-2016-10-747477. PMID: 28143881

Supplemental Content

Table of contents

    Practice guidelines

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