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Abnormal circulating tyrosine concentration

MedGen UID:
1684690
•Concept ID:
C5139049
•
Finding
Synonym: Abnormality of tyrosine metabolism
 
HPO: HP:0010917

Definition

Any deviation from the normal concentration of tyrosine in the blood circulation. [from HPO]

Professional guidelines

PubMed

Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.
Lim M, Puttick S, Houston ZH, Thurecht KJ, Kalita-de Croft P, Mahler S, Rose SE, Jeffree RL, Mazzieri R, Dolcetti R, Lakhani SR, Saunus JM
Int J Mol Sci 2019 Mar 14;20(6) doi: 10.3390/ijms20061280. PMID: 30875730Free PMC Article

Recent clinical studies

Etiology

Vascular endothelial growth factors and risk of cardio-renal events: Results from the CREDENCE trial.
Januzzi JL Jr, Liu Y, Sattar N, Yavin Y, Pollock CA, Butler J, Jardine M, Heerspink HJL, Masson S, Breyer M, Hansen MK
Am Heart J 2024 May;271:38-47. Epub 2024 Feb 22 doi: 10.1016/j.ahj.2024.02.016. PMID: 38401646
Preeclampsia at term: evidence of disease heterogeneity based on the profile of circulating cytokines and angiogenic factors.
Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516

Diagnosis

Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
A decrease in D-dimer concentration and an occurrence of skin rash as iatrogenic events and complementary predictors of survival in lung cancer patients treated with EGFR tyrosine kinase inhibitors.
Zaborowska-Szmit M, Kowalski DM, Piórek A, Krzakowski M, Szmit S
Pharmacol Rep 2016 Dec;68(6):1140-1148. Epub 2016 Jul 20 doi: 10.1016/j.pharep.2016.07.003. PMID: 27588390
Functional evaluation of circulating hematopoietic progenitors in Noonan syndrome.
Timeus F, Crescenzio N, Baldassarre G, Doria A, Vallero S, Foglia L, Pagliano S, Rossi C, Silengo MC, Ramenghi U, Fagioli F, Cordero di Montezemolo L, Ferrero GB
Oncol Rep 2013 Aug;30(2):553-9. Epub 2013 Jun 11 doi: 10.3892/or.2013.2535. PMID: 23756559Free PMC Article
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516

Therapy

Vascular endothelial growth factors and risk of cardio-renal events: Results from the CREDENCE trial.
Januzzi JL Jr, Liu Y, Sattar N, Yavin Y, Pollock CA, Butler J, Jardine M, Heerspink HJL, Masson S, Breyer M, Hansen MK
Am Heart J 2024 May;271:38-47. Epub 2024 Feb 22 doi: 10.1016/j.ahj.2024.02.016. PMID: 38401646
Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.
Lim M, Puttick S, Houston ZH, Thurecht KJ, Kalita-de Croft P, Mahler S, Rose SE, Jeffree RL, Mazzieri R, Dolcetti R, Lakhani SR, Saunus JM
Int J Mol Sci 2019 Mar 14;20(6) doi: 10.3390/ijms20061280. PMID: 30875730Free PMC Article
A decrease in D-dimer concentration and an occurrence of skin rash as iatrogenic events and complementary predictors of survival in lung cancer patients treated with EGFR tyrosine kinase inhibitors.
Zaborowska-Szmit M, Kowalski DM, Piórek A, Krzakowski M, Szmit S
Pharmacol Rep 2016 Dec;68(6):1140-1148. Epub 2016 Jul 20 doi: 10.1016/j.pharep.2016.07.003. PMID: 27588390
Circulating angiogenic factors and placental abruption.
Signore C, Mills JL, Qian C, Yu K, Lam C, Epstein FH, Karumanchi SA, Levine RJ
Obstet Gynecol 2006 Aug;108(2):338-44. doi: 10.1097/01.AOG.0000216014.72503.09. PMID: 16880304
Disorders of prolactin and growth hormone secretion.
Ho KY, Evans WS, Thorner MO
Clin Endocrinol Metab 1985 Feb;14(1):1-32. doi: 10.1016/s0300-595x(85)80063-3. PMID: 3926353

Prognosis

Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.
Lim M, Puttick S, Houston ZH, Thurecht KJ, Kalita-de Croft P, Mahler S, Rose SE, Jeffree RL, Mazzieri R, Dolcetti R, Lakhani SR, Saunus JM
Int J Mol Sci 2019 Mar 14;20(6) doi: 10.3390/ijms20061280. PMID: 30875730Free PMC Article
A decrease in D-dimer concentration and an occurrence of skin rash as iatrogenic events and complementary predictors of survival in lung cancer patients treated with EGFR tyrosine kinase inhibitors.
Zaborowska-Szmit M, Kowalski DM, Piórek A, Krzakowski M, Szmit S
Pharmacol Rep 2016 Dec;68(6):1140-1148. Epub 2016 Jul 20 doi: 10.1016/j.pharep.2016.07.003. PMID: 27588390
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516

Clinical prediction guides

Preeclampsia at term: evidence of disease heterogeneity based on the profile of circulating cytokines and angiogenic factors.
Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516
Neurotrophins and neurotrophin receptors in allergic asthma.
Nassenstein C, Kerzel S, Braun A
Prog Brain Res 2004;146:347-67. doi: 10.1016/S0079-6123(03)46022-6. PMID: 14699973

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