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Hematologic Malignancy-Associated Skin Squamous Cell Carcinoma

MedGen UID:
1685245
•Concept ID:
C5205447
•
Neoplastic Process
Synonym: Hematologic Malignancy-Associated Cutaneous Squamous Cell Carcinoma

Definition

A squamous cell carcinoma that arises from the skin in a patient with a history of hematologic malignancy, usually non-Hodgkin lymphoma or chronic lymphocytic leukemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHematologic Malignancy-Associated Skin Squamous Cell Carcinoma

Recent clinical studies

Etiology

Sebaceous carcinoma in the clinical setting of non-Hodgkin lymphoma: the Mayo Clinic experience.
Chang TW, Weaver AL, Brewer JD
Int J Dermatol 2013 Oct;52(10):1210-4. Epub 2013 May 15 doi: 10.1111/j.1365-4632.2012.05627.x. PMID: 23675639
Cutaneous sarcoidosis and malignancy: An association between sarcoidosis with skin manifestations and systemic neoplasia.
Alexandrescu DT, Kauffman CL, Ichim TE, Riordan NH, Kabigting F, Dasanu CA
Dermatol Online J 2011 Jan 15;17(1):2. PMID: 21272493
Dense lymphocytic infiltrates associated with non-melanoma skin cancer in patients with chronic lymphocytic leukemia.
Wilson ML, Elston DM, Tyler WB, Marks VJ, Ferringer T
Dermatol Online J 2010 Mar 15;16(3):4. PMID: 20233561
Treatments for psoriasis and the risk of malignancy.
Patel RV, Clark LN, Lebwohl M, Weinberg JM
J Am Acad Dermatol 2009 Jun;60(6):1001-17. Epub 2009 Apr 2 doi: 10.1016/j.jaad.2008.12.031. PMID: 19344980

Diagnosis

Sebaceous carcinoma in the clinical setting of non-Hodgkin lymphoma: the Mayo Clinic experience.
Chang TW, Weaver AL, Brewer JD
Int J Dermatol 2013 Oct;52(10):1210-4. Epub 2013 May 15 doi: 10.1111/j.1365-4632.2012.05627.x. PMID: 23675639
Cutaneous sarcoidosis and malignancy: An association between sarcoidosis with skin manifestations and systemic neoplasia.
Alexandrescu DT, Kauffman CL, Ichim TE, Riordan NH, Kabigting F, Dasanu CA
Dermatol Online J 2011 Jan 15;17(1):2. PMID: 21272493
Dense lymphocytic infiltrates associated with non-melanoma skin cancer in patients with chronic lymphocytic leukemia.
Wilson ML, Elston DM, Tyler WB, Marks VJ, Ferringer T
Dermatol Online J 2010 Mar 15;16(3):4. PMID: 20233561
Sweet syndrome in patients with solid tumors.
Cohen PR, Holder WR, Tucker SB, Kono S, Kurzrock R
Cancer 1993 Nov 1;72(9):2723-31. doi: 10.1002/1097-0142(19931101)72:9<2723::aid-cncr2820720933>3.0.co;2-f. PMID: 8402496

Therapy

Humoral hypercalcaemia of malignancy associated with a gigantic cutaneous squamous cell carcinoma.
Elantably D, Al Armashi AR, Hammad F, Alkrekshi A
BMJ Case Rep 2022 Nov 2;15(11) doi: 10.1136/bcr-2022-250598. PMID: 36323452Free PMC Article
Treatments for psoriasis and the risk of malignancy.
Patel RV, Clark LN, Lebwohl M, Weinberg JM
J Am Acad Dermatol 2009 Jun;60(6):1001-17. Epub 2009 Apr 2 doi: 10.1016/j.jaad.2008.12.031. PMID: 19344980

Prognosis

Sebaceous carcinoma in the clinical setting of non-Hodgkin lymphoma: the Mayo Clinic experience.
Chang TW, Weaver AL, Brewer JD
Int J Dermatol 2013 Oct;52(10):1210-4. Epub 2013 May 15 doi: 10.1111/j.1365-4632.2012.05627.x. PMID: 23675639

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