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Differentiated Penile Intraepithelial Neoplasia, Human Papillomavirus-Independent

MedGen UID:
1693110
Concept ID:
C5206633
Neoplastic Process
Synonyms: Differentiated (Simplex) PeIN; Differentiated (Simplex) Penile Intraepithelial Neoplasia; Differentiated PeIN; Differentiated PeIN (penile intraepithelial neoplasia); Differentiated Penile Intraepithelial Neoplasia; Differentiated penile intraepithelial neoplasia; Differentiated Penile Intraepithelial Neoplasia, HPV-Independent
SNOMED CT: Differentiated PeIN (penile intraepithelial neoplasia) (816980006); Differentiated penile intraepithelial neoplasia (816980006)

Definition

Intraepithelial neoplasia of the penis that is not caused by human papillomavirus infection. It usually presents as a solitary white or pink macule or plaque that may be slightly elevated. A background of long-standing lichen sclerosus is often present. It is characterized by a thickened epithelium, subtle abnormal cellular maturation, and atypical basal layer cells. Parakeratosis is common. (WHO 2016) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDifferentiated Penile Intraepithelial Neoplasia, Human Papillomavirus-Independent

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